Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jeffrey W. Abt"'
Synthesis of Nucleoside Libraries on Solid Support. I. N2,N6‐Disubstituted Diaminopurine Nucleosides
Autor:
Haoyun An, Jean-Luc Girardet, Jeffrey W. Abt, Roberto Amador, Zhi Hong, Esmir Gunic, Frank Rong
Publikováno v:
Nucleosides, Nucleotides & Nucleic Acids. 23:495-499
Starting with 2‐iodo‐6‐chloro‐9‐(β‐D‐ribofuranosyl)purine, a library of more than 1,300 N2,N6‐polysubstituted diaminopurine nucleosides was created. The starting material was condensed with a polystyrene monomethoxytrityl resin and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27b318c409b70a0f7c96e0f7c83a9e4b
https://doi.org/10.1081/ncn-120028342
https://doi.org/10.1081/ncn-120028342
Publikováno v:
Journal of Combinatorial Chemistry. 5:851-859
A versatile solid phase combinatorial approach was developed and utilized for the rapid synthesis of new 2'-O-methylcytidine nucleoside libraries 1-7 containing 672 compounds with 3'-deoxy-3'-C-methyl, 3'-deoxy-3'-C-hydroxymethyl, and 5-alkyl/alkynyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f21ed55fddf749e68359e005c9ff1dfe
https://doi.org/10.1021/cc0300199
https://doi.org/10.1021/cc0300199
Autor:
Qazi Habib, Chamakura V N S Varaprasad, Jingfan Huang, Frank Rong, Haoyun An, David Y. Li, Jeffrey W. Abt, Zhi Hong
Publikováno v:
Tetrahedron. 59:2297-2307
A versatile parallel solid-phase combinatorial strategy was developed for the synthesis of large nucleoside libraries. Twelve libraries L1-12 of 1152 novel exocyclic triazinylamino nucleosides and one library L13 of 82 new substituted clitocine deriv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9adbd59f19e186fad490f6a3e005cafe
https://doi.org/10.1016/s0040-4020(03)00211-4
https://doi.org/10.1016/s0040-4020(03)00211-4
Autor:
Jeffrey T. Laydon, Glenn A. Hofmann, Jeffrey C. Boehm, Jeffrey W. Abt, Margaret E. Soreson, Susan M. Fier-Thompson, Juanita M. Smietana, Peter R. Young, Timothy Francis Gallagher, John C. Lee, Mary Jane Blumenthal, Arnold J. Krog, Ralph Hall, Dennis Lee, Paul Elliot Bender, Karl F. Erhard, Ravi Shanker Garigipati, Jerry L. Adams, Peter C. McDonnell, George Leslie Seibel, Shouki Kassis, Sanjay Kumar, Peter L. Sheldrake
Publikováno v:
Bioorganicmedicinal chemistry. 5(1)
Members of three classes of pyridinylimidazoles bind with varying affinities to CSBP (p38) kinase which is a member of a stress-induced signal transduction pathway. Based upon SAR and protein homology modeling, the pharmacophore and three potential m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4e122df6ffe903523b617fc84550c0c
https://pubmed.ncbi.nlm.nih.gov/9043657
https://pubmed.ncbi.nlm.nih.gov/9043657
Autor:
W. DAVID NES, EDWARD J. PARISH, JAMES M. TRZASKOS, Efraim Lewinsohn, Mark Gijzen, Rodney B. Croteau, Katrina Cornish, Richard F. Taylor, H. C. Rilling, L. M. Leining, E. Bruenger, D. Lever, W. W. Epstein, William A. Maltese, B. Therese Kinsella, Kathleen M. Sheridan, Scott A. Biller, Michael J. Sofia, Jeffrey W. Abt, Barbara DeLange, John K. Dickson, Cornelia Forster, Eric M. Gordon, Thomas Harrity, David R. Magnin, Joseph Marretta, Lois C. Rich, Carl P. Ciosek, F. R. Taylor, Leah L. Frye, Deborah A. Leonard, Stephen R. Parker, E. I. Mercer, L. Cattel, M. Ceruti, G. Balliano, F. Viola, Neil S. Ryder, Anton Stuetz, Peter Nussbaumer, James A. Svoboda, David J. Chitwood, H. Vanden Bossche, P. Marichal, M-C. Coene, G. Willemsens, L. Le Jeune, W. Cools, H. Verhoeven, Glenn W. Patterson, Harry Rudney, Arun K. Gupta, Norman D. Lees, Beth A. Arthington, Martin Bard
