Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Jeffrey W Streb"'
Autor:
Jeffrey W Streb, Xiaochun Long, Ting-Hein Lee, Qiang Sun, Chad M Kitchen, Mary A Georger, Orazio J Slivano, William S Blaner, Daniel W Carr, Irwin H Gelman, Joseph M Miano
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18538 (2011)
Retinoids are used clinically to treat a number of hyper-proliferative disorders and have been shown in experimental animals to attenuate vascular occlusive diseases, presumably through nuclear receptors bound to retinoic acid response elements (RARE
Externí odkaz:
https://doaj.org/article/140e7afc289a4e2198d80a2ce8f33b11
Publikováno v:
Ultrasound Quarterly. 35:99-102
Hepatic and renal lesions detected during ultrasound examinations frequently require subsequent contrast-enhanced computed tomography (CT) or magnetic resonance imaging (MRI) for characterization, delaying time to imaging diagnosis and increasing ove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::481f3a868e99e6a4e03c5ead66b324d0
https://doi.org/10.1097/ruq.0000000000000375
https://doi.org/10.1097/ruq.0000000000000375
Publikováno v:
Development. 139:2878-2890
REST is a master repressor of neuronal genes; however, whether it has any role during nervous system development remains largely unknown. Here, we analyzed systematically the role of REST in embryonic stem cells and multipotent neural stem/progenitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::204a02c022dc9179bdcfe2cfe8eb4107
https://doi.org/10.1242/dev.074765
https://doi.org/10.1242/dev.074765
Autor:
Seock-Ah Im, Hyun Soon Jong, Jung Hyun Park, Jeffrey W. Streb, Ju-Hee Lee, Moon Chang Choi, Yang Ui Lee, Tae-You Kim, Do-Youn Oh, Yung-Jue Bang, Sung Hak Kim
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 40:2534-2543
A-kinase anchoring protein 12 (AKAP12) is known to function as a scaffold protein and as a putative tumor suppressor. However, little is known about the biological role of AKAP12 in hepatic cells. In this study, we performed micro-array analysis to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73b126d6f1bca3e5cef21a26b0faebdf
https://doi.org/10.1016/j.biocel.2008.04.020
https://doi.org/10.1016/j.biocel.2008.04.020
Autor:
Nienwen Chow, Jeffrey W. Streb, Jiyuan Chen, Andrew I. Brooks, William E. Van Nostrand, Rashid Deane, Berislav V. Zlokovic, Robert D. Bell, Joseph M. Miano
Publikováno v:
Proceedings of the National Academy of Sciences. 104:823-828
Cerebral angiopathy contributes to cognitive decline and dementia in Alzheimer's disease (AD) through cerebral blood flow (CBF) reductions and dysregulation. We report vascular smooth muscle cells (VSMC) in small pial and intracerebral arteries, whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fd05e04876898dd397082fd6b66dd16
https://doi.org/10.1073/pnas.0608251104
https://doi.org/10.1073/pnas.0608251104
Autor:
Christian J. Stoeckert, Yumei Yang, Qiang Sun, Guang Chen, Joseph M. Miano, Xiaochun Long, Jeffrey W. Streb
Publikováno v:
Genome Research. 16:197-207
Serum response factor (SRF) binds a 1216-fold degenerate cis element known as the CArG box. CArG boxes are found primarily in muscle- and growth-factor-associated genes although the full spectrum of functional CArG elements in the genome (the CArGome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fb80b7cda751546eadb814a4a22b947
https://doi.org/10.1101/gr.4108706
https://doi.org/10.1101/gr.4108706
Autor:
Joseph M. Miano, Jeffrey W. Streb
Publikováno v:
Journal of Biological Chemistry. 280:28007-28014
A kinase anchoring proteins (AKAPs) assemble and compartmentalize multiprotein signaling complexes at discrete subcellular locales and thus confer specificity to transduction cascades using ubiquitous signaling enzymes, such as protein kinase A. Intr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92724de93ba1a7f3a5d3cdeac793e02d
https://doi.org/10.1074/jbc.m414017200
https://doi.org/10.1074/jbc.m414017200
Publikováno v:
Journal of Biological Chemistry. 279:56014-56023
A Kinase Anchoring Protein 12 (AKAP12; also known as src-suppressed C kinase substrate (SSeCKS) and Gravin) is a multivalent anchoring protein with tumor suppressor activity. Although expression of AKAP12 has been examined in a number of contexts, it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45b24d64b90e75b266b58524492f645a
https://doi.org/10.1074/jbc.m408828200
https://doi.org/10.1074/jbc.m408828200
Autor:
Joseph M. Miano, Jeffrey W. Streb
Publikováno v:
Current Drug Target -Cardiovascular & Hematological Disorders. 3:31-57
Retinoids, the natural and synthetic derivatives of vitamin A, exert broad biological effects and have been used clinically to treat a variety of dermatological and neoplastic diseases. The principal mode of action of many retinoids is through the bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f6aa2af95dc351a8917331740cd0b84
https://doi.org/10.2174/1568006033337393
https://doi.org/10.2174/1568006033337393
Autor:
Joseph M. Miano, Huang Guo, Berislav V. Zlokovic, Xiaochun Long, Itender Singh, Rashid Deane, Nienwen Chow, William E. Van Nostrand, Jeffrey W. Streb, Abhay P. Sagare, Robert D. Bell, Anna Rubio
Publikováno v:
Nature cell biology. 11(2)
Amyloid beta-peptide (Abeta) deposition in cerebral vessels contributes to cerebral amyloid angiopathy (CAA) in Alzheimer's disease (AD). Here, we report that in AD patients and two mouse models of AD, overexpression of serum response factor (SRF) an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27653ecf88a4712525e4d3ff3f121678
https://pubmed.ncbi.nlm.nih.gov/19188916
https://pubmed.ncbi.nlm.nih.gov/19188916