Zobrazeno 1 - 10
of 520
pro vyhledávání: '"Jeffrey W Clark"'
Autor:
Jeffrey A Meyerhardt, Sunil Kumar, Jessica A Zerillo, Aparna Parikh, James M Cleary, Scott Rodig, Benjamin Schlechter, Kimmie Ng, Stephanie K Dougan, Nora Horick, Glenn J Hanna, Andrew L Coveler, Anuj K Patel, Nadine J McCleary, Douglas A Rubinson, Jeffrey W Clark, Kent Mouw, Kathleen Pfaff, Thomas A Abrams, Matthew B Yurgelun, Eliezer M Van Allen, S Jennifer Wang, Leah H Biller, Harshabad Singh, Emma L Welsh, Brandon M Huffman, Lestat R Ali, Megan T Hoffman, Katherine A Metayer, Shayla Murray, Alexandra Bird, Jennifer A Chan, Wolfram Goessling, Jeffrey S Wisch, Brendan Reardon, Robert J Mayer, Catherine Del Vecchio Fitz, Charlotte Kuperwasser
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 1 (2024)
Background Recent trials suggest that programmed cell death 1 (PD-1)-directed immunotherapy may be beneficial for some patients with anal squamous cell carcinoma and biomarkers predictive of response are greatly needed.Methods This multicenter phase
Externí odkaz:
https://doaj.org/article/3355b66d86a3433d9514838bcb4205a5
Autor:
Amna Zafar, Zsofia D Drobni, Matthew Lei, Carlos A Gongora, Thiago Quinaglia, Uvette Y Lou, Ramya Mosarla, Sean P Murphy, Maeve Jones-O'Connor, Ali Mahmood, Sarah Hartmann, Hannah K Gilman, Colin D Weekes, Ryan Nipp, John R Clark, Jeffrey W Clark, Lawrence S Blaszkowsky, Erica Tavares, Tomas G Neilan
Publikováno v:
PLoS ONE, Vol 17, Iss 4, p e0265767 (2022)
BackgroundCoronary vasospasm is a known side effect of 5-FU (fluorouracil) therapy. Beyond switching to non-5FU-based chemotherapy, there are no established treatments for 5-FU associated coronary vasospam. Our objective was to assess the safety and
Externí odkaz:
https://doaj.org/article/002769a21d784536b283e8e05bd4b73d
Autor:
Hui Zheng, Eirini Pectasides, Mohamed Uduman, Charles S Fuchs, James M Cleary, Adam J Bass, Jérémy Augustin, Leonie K de Klerk, Anuj K Patel, Sarah Derks, Nihal Raman, Fahire G Akarca, Nadine J McCleary, Douglas A Rubinson, Jeffrey W Clark, Bridget Fitzpatrick, Lauren K Brais, Megan E Cavanaugh, Amanda J Rode, Melissa G Jean, Patrick H Lizotte, Matthew J Nazzaro, Peter C Enzinger
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 9 (2021)
Externí odkaz:
https://doaj.org/article/88b5dffda1124385a9d172a7073bce20
Autor:
Surendra Pal Chaudhary, Stephanie Reyes, Matthew L Chase, Aparna Govindan, Lei Zhao, Jay Luther, Irun Bhan, Emily Bethea, Joseph W Franses, Elizabeth Paige Walsh, Leigh Anne Dageford, Shoko Kimura, Nahel Elias, Heidi Yeh, James Markman, Adel Bozorgzadeh, Kenneth Tanabe, Cristina Ferrone, Andrew X Zhu, Karin Andersson, Michael Thiim, Onofrio Antonio Catalano, Avinash Kambadakone, Parsia A Vagefi, Motaz Qadan, Daniel Pratt, Nikroo Hashemi, Kathleen E Corey, Joseph Misdraji, Lipika Goyal, Jeffrey W Clark
Publikováno v:
The Oncologist. 28:341-350
Background Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are the leading causes of hepatocellular carcinoma (HCC) worldwide. Limited data exist on surgical outcomes for NAFLD/NASH-related HCC compared with other H
Autor:
Yves Boucher, Jessica M. Posada, Sonu Subudhi, Ashwin S. Kumar, Spencer R. Rosario, Liqun Gu, Heena Kumra, Mari Mino-Kenudson, Nilesh P. Talele, Dan G. Duda, Dai Fukumura, Jennifer Y. Wo, Jeffrey W. Clark, David P. Ryan, Carlos Fernandez-Del Castillo, Theodore S. Hong, Mikael J. Pittet, Rakesh K. Jain
Publikováno v:
Clinical Cancer Research. 29:1605-1619
Purpose: Adding losartan (LOS) to FOLFIRINOX (FFX) chemotherapy followed by chemoradiation (CRT) resulted in 61% R0 surgical resection in our phase II trial in patients with locally advanced pancreatic cancer (LAPC). Here we identify potential mechan
Autor:
Jun Tian, Jonathan H. Chen, Sherry X. Chao, Karin Pelka, Marios Giannakis, Julian Hess, Kelly Burke, Vjola Jorgji, Princy Sindurakar, Jonathan Braverman, Arnav Mehta, Tomonori Oka, Mei Huang, David Lieb, Maxwell Spurrell, Jill N. Allen, Thomas A. Abrams, Jeffrey W. Clark, Andrea C. Enzinger, Peter C. Enzinger, Samuel J. Klempner, Nadine J. McCleary, Jeffrey A. Meyerhardt, David P. Ryan, Matthew B. Yurgelun, Katie Kanter, Emily E. Van Seventer, Islam Baiev, Gary Chi, Joy Jarnagin, William B. Bradford, Edmond Wong, Alexa G. Michel, Isobel J. Fetter, Giulia Siravegna, Angelo J. Gemma, Arlene Sharpe, Shadmehr Demehri, Rebecca Leary, Catarina D. Campbell, Omer Yilmaz, Gad A. Getz, Aparna R. Parikh, Nir Hacohen, Ryan B. Corcoran
Publikováno v:
Nature Medicine. 29:458-466
While BRAF inhibitor combinations with EGFR and/or MEK inhibitors have improved clinical efficacy in BRAFV600E colorectal cancer (CRC), response rates remain low and lack durability. Preclinical data suggest that BRAF/MAPK pathway inhibition may augm
Autor:
Zhi Ven Fong, Fidel Lopez Verdugo, Carlos Fernandez-del Castillo, Cristina R Ferrone, Jill N Allen, Lawrence S Blaszkowsky, Jeffrey W Clark, Aparna R Parikh, David P Ryan, Colin D Weekes, Theodore S Hong, Jennifer Y Wo, Keith D Lillemoe, Motaz Qadan
Publikováno v:
Journal of the American College of Surgeons. 236:1126-1136
Autor:
Rakesh K. Jain, Mikael J. Pittet, Theodore S. Hong, Carlos Fernandez-Del Castillo, David P. Ryan, Jeffrey W. Clark, Jennifer Y. Wo, Dai Fukumura, Dan G. Duda, Nilesh P. Talele, Mari Mino-Kenudson, Heena Kumra, Liqun Gu, Spencer R. Rosario, Ashwin S. Kumar, Sonu Subudhi, Jessica M. Posada, Yves Boucher
Venn plots and selected GSEA pathways.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32aa766e188dfb7efdbae9354c85712c
https://doi.org/10.1158/1078-0432.22633054.v1
https://doi.org/10.1158/1078-0432.22633054.v1
Autor:
Rakesh K. Jain, Mikael J. Pittet, Theodore S. Hong, Carlos Fernandez-Del Castillo, David P. Ryan, Jeffrey W. Clark, Jennifer Y. Wo, Dai Fukumura, Dan G. Duda, Nilesh P. Talele, Mari Mino-Kenudson, Heena Kumra, Liqun Gu, Spencer R. Rosario, Ashwin S. Kumar, Sonu Subudhi, Jessica M. Posada, Yves Boucher
Longitudinal analysis of circulating biomarkers in the plasma of treated patients.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e1f148ae1cbc18e85df3cde2c1dc852
https://doi.org/10.1158/1078-0432.22633018.v1
https://doi.org/10.1158/1078-0432.22633018.v1
Autor:
David T. Ting, Benjamin D. Greenbaum, Peter J. Park, Kathleen H. Burns, David R. Walt, Shelley L. Berger, Theodore S. Hong, Martin J. Aryee, Miguel N. Rivera, Vikram Deshpande, Ryan B. Corcoran, David P. Ryan, Jennifer Y. Wo, Lipika Goyal, Jeffrey W. Clark, Lawrence S. Blaszkowsky, Jill N. Allen, Hui Zheng, Yasmeen Senussi, Padric M. Garden, Limor Cohen, Vishal Thapar, Matteo Ligorio, Kshitij S. Arora, Niyati Desai, Linda T. Nieman, Michael J. Raabe, Jasmin Joseph-Chazan, Chenyue Lu, Eric C. Tai, Kevin D. Vo, Emily E. Van Seventer, Richard Y. Ebright, Nova Xu, Antuan V. Tran, Stefanie Gerstberger, Annamaria Szabolcs, Charly R. Good, Katherine A. Alexander, Connie Wu, Martin S. Taylor, Christopher Jaicks, Katherine H. Xu, Chong Chu, Anupriya S. Kulkarni, Eunae You, Alexander Solovyov, Aparna R. Parikh, Mihir Rajurkar
Altered RNA expression of repetitive sequences and retrotransposition are frequently seen in colorectal cancer, implicating a functional importance of repeat activity in cancer progression. We show the nucleoside reverse transcriptase inhibitor 3TC t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::872fbbb37783ee4cbd8e559e5d98142a
https://doi.org/10.1158/2159-8290.c.6549619.v1
https://doi.org/10.1158/2159-8290.c.6549619.v1