Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jeffrey Trent"'
Autor:
Xianbing Zhu, Zheng Fu, Shary Y. Chen, Dionzie Ong, Giulio Aceto, Rebecca Ho, Jutta Steinberger, Anie Monast, Virginie Pilon, Eunice Li, Monica Ta, Kyle Ching, Bianca N. Adams, Gian L. Negri, Luc Choiniere, Lili Fu, Kitty Pavlakis, Patrick Pirrotte, Daina Z. Avizonis, Jeffrey Trent, Bernard E. Weissman, Ramon I. Klein Geltink, Gregg B. Morin, Morag Park, David G. Huntsman, William D. Foulkes, Yemin Wang, Sidong Huang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract SMARCA4 (BRG1) and SMARCA2 (BRM) are the two paralogous ATPases of the SWI/SNF chromatin remodeling complexes frequently inactivated in cancers. Cells deficient in either ATPase have been shown to depend on the remaining counterpart for surv
Externí odkaz:
https://doaj.org/article/9b0a23025ed145939844545536f59b3f
Publikováno v:
BioTechniques, Vol 35, Iss 3, Pp 580-593 (2003)
New technologies have greatly increased the scientist's ability to investigate complex molecular interactions that occur in cancer development and to identify genetic alterations and drug targets. However, these new capabilities have not accelerated
Externí odkaz:
https://doaj.org/article/7f6cc8fdcbac4a0f96d6a934a45ed254
Autor:
Melissa Paoloni, Craig Webb, Christina Mazcko, David Cherba, William Hendricks, Susan Lana, E J Ehrhart, Brad Charles, Heather Fehling, Leena Kumar, David Vail, Michael Henson, Michael Childress, Barbara Kitchell, Christopher Kingsley, Seungchan Kim, Mark Neff, Barbara Davis, Chand Khanna, Jeffrey Trent
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90028 (2014)
BackgroundMolecularly-guided trials (i.e. PMed) now seek to aid clinical decision-making by matching cancer targets with therapeutic options. Progress has been hampered by the lack of cancer models that account for individual-to-individual heterogene
Externí odkaz:
https://doaj.org/article/55faf0c024234b4cb92c74818bed7656
Autor:
Giselle L. Saulner Sholler, Jacqueline Kraveka, Genevieve Bergendahl, Elizabeth Lewis, William Ferguson, Abhinav Nagulapally, Karl Dykema, Valerie Brown, Michael Isakoff, Joseph Junewick, Deanna Mitchell, Don Eslin, Virginia Harrod, William Roberts, Javier Oesterheld, Randy Wada, Jawhar Rawwas, Devang Pastakia, Kevin Ginn, Raya Saab, Kevin Bielamowicz, Jason Glover, Eugenia Chang, Gina Hanna, Daniel Enriquez, Tyler Izatt, Rebecca Halperin, Sara Byron, William Hendricks, Jeffrey Trent
Publikováno v:
Cancer Research. 83:CT089-CT089
Background: Children with relapsed CNS tumors, neuroblastoma, sarcomas, and other rare solid tumors face poor outcomes. Here we describe a study to determine the feasibility of leveraging genomic profiling results within a molecular tumor board (MTB)
Autor:
Winnie S, Liang, William, Hendricks, Jeffrey, Kiefer, Jessica, Schmidt, Shobana, Sekar, John, Carpten, David W, Craig, Jonathan, Adkins, Lori, Cuyugan, Zarko, Manojlovic, Rebecca F, Halperin, Adrienne, Helland, Sara, Nasser, Christophe, Legendre, Laurence H, Hurley, Karthigayini, Sivaprakasam, Douglas B, Johnson, Holly, Crandall, Klaus J, Busam, Victoria, Zismann, Valerie, Deluca, Jeeyun, Lee, Aleksandar, Sekulic, Charlotte E, Ariyan, Jeffrey, Sosman, Jeffrey, Trent
Publikováno v:
Genome research. 27(4)
Genomic analyses of cutaneous melanoma (CM) have yielded biological and therapeutic insights, but understanding of non-ultraviolet (UV)-derived CMs remains limited. Deeper analysis of acral lentiginous melanoma (ALM), a rare sun-shielded melanoma sub
Autor:
Heli Nevanlinna, Robert Winqvist, Pia Vahteristo, Minna Allinen, Suh Hang Hank Juo, Joan E. Bailey-Wilson, J. Leisti, Tommi Kainu, MaryPat Jones, Elizabeth Gillanders, Pia Huusko, Laura Sarantaus, Katrin Rapakko, Carol Markey, Guillermo Blanco, Jeffrey Trent, Ulla Puistola, Derek Gildea, Carl Blomqvist, Paula Vehmanen, Hannaleena Eerola, Diane Freas-Lutz, Olli-P Kallioniemi
Publikováno v:
European journal of human genetics : EJHG. 12(2)
Only a proportion of breast cancer families has germline mutations in the BRCA1 or BRCA2 genes, suggesting the presence of additional susceptibility genes. Finding such genes by linkage analysis has turned out to be difficult due to the genetic heter
Autor:
Albert J, Fornace, Sally A, Amundson, Khanh T, Do, Paul, Meltzer, Jeffrey, Trent, Michael, Bittner
Publikováno v:
Military medicine. 167
Using a human myeloid tumor cell line (ML-1), we detected induction of mRNA expression of several stress-responsive genes by doses of gamma rays as low as 2 cGy. For instance, the dose response for induction of CIP1/WAF1 and GADD45 appears to be line
Autor:
Curtis A. Pettaway, Rick A. Kittles, Raul Mejia, Chiledum Ahaghotu, Norma Foster, John Carpten, Pamela Roberson, Joan E. Bailey-Wilson, Michael Obeikwe, Edna Johnson, Paulette Furbert-Harris, Jacqueline Frost, Gerald Hoke, James Bennett, Francis Collins, Carol Meegan, Sally P. Weinrich, Agnes Baffoe-Bonnie, Louise Faison-Smith, Jeffrey Trent, Georgia M. Dunston, Terry Mason, Kate Berg, Srinivasan Vijayakumar, Cheryl Simpson, Isaac Powell, Charmaine D.M. Royal, William Boykin
Publikováno v:
Scopus-Elsevier
The African American Hereditary Prostate Cancer (AAHPC) Study is an ongoing multicenter genetic linkage study organized by Howard University and the National Human Genome Research Institute (NHGRI), with support from the Office for Research on Minori
Publikováno v:
Nature Genetics. 23:75-75
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