Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jeffrey Townsend"'
Autor:
T. Déirdre Hollingsworth, Emily R. Adams, Roy M. Anderson, Katherine Atkins, Sarah Bartsch, María-Gloria Basáñez, Matthew Behrend, David J. Blok, Lloyd A. C. Chapman, Luc Coffeng, Orin Courtenay, Ron E. Crump, Sake J. de Vlas, Andy Dobson, Louise Dyson, Hajnal Farkas, Alison P. Galvani, Manoj Gambhir, David Gurarie, Michael A. Irvine, Sarah Jervis, Matt J. Keeling, Louise Kelly-Hope, Charles King, Bruce Y. Lee, Epke A. Le Rutte, Thomas M. Lietman, Martial Ndeffo-Mbah, Graham F. Medley, Edwin Michael, Abhishek Pandey, Jennifer K. Peterson, Amy Pinsent, Travis C. Porco, Jan Hendrik Richardus, Lisa Reimer, Kat S. Rock, Brajendra K. Singh, Wilma Stolk, Subramanian Swaminathan, Steve J. Torr, Jeffrey Townsend, James Truscott, Martin Walker, Alexandra Zoueva, NTD Modelling Consortium
Publikováno v:
Parasites & Vectors, Vol 8, Iss 1, Pp 1-28 (2015)
Abstract Quantitative analysis and mathematical models are useful tools in informing strategies to control or eliminate disease. Currently, there is an urgent need to develop these tools to inform policy to achieve the 2020 goals for neglected tropic
Externí odkaz:
https://doaj.org/article/d9edd51f83d04fe2a0d554a60e82a78f
Publikováno v:
Cancer Research. 83:P5-14
Estrogen-receptor positive (ER+) and human epidermal growth factor receptor positive (HER2+) subtypes of breast cancers feature distinct histopathologies and prognoses. Their molecular profiles inform subtype-specific treatment combinations and possi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fff3cca9de7a799e4f7cea35142e5a50
https://doi.org/10.1158/1538-7445.sabcs22-p5-14-07
https://doi.org/10.1158/1538-7445.sabcs22-p5-14-07
Publikováno v:
Cancer research.
Somatic nucleotide mutations can contribute to cancer cell survival, proliferation, and pathogenesis. Although research has focused on identifying which mutations are “drivers” versus “passengers," quantifying the proliferative effects of speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2216b84e50d8f6f6fb613223080720a
https://pubmed.ncbi.nlm.nih.gov/36469362
https://pubmed.ncbi.nlm.nih.gov/36469362
Autor:
J Nicholas Fisk, Stephen Gaffney, Katerina Politi, Scott Gettinger, Fernando de Miguel, Jeffrey Townsend
Publikováno v:
Cancer Research. 83:126-126
The acquisition of resistance by tumors to targeted molecular therapies remains one of the greatest challenges in precision medicine. Evolutionary techniques, such as phylogenetic analysis and the thoughtful calculation of selection intensities, are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cf767560be937c160885391fe311da8
https://doi.org/10.1158/1538-7445.am2023-126
https://doi.org/10.1158/1538-7445.am2023-126
Publikováno v:
Molecular Biology and Evolution. 39
Mutational processes in tumors create distinctive patterns of mutations, composed of neutral “passenger” mutations and oncogenic drivers that have quantifiable effects on the proliferation and survival of cancer cell lineages. Increases in prolif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::166726da5846bdc77511f1501797f0c6
https://doi.org/10.1093/molbev/msac084
https://doi.org/10.1093/molbev/msac084
Abstract A055: Altered RNA splicing causes pancreatic cancer and exposes a therapeutic vulnerability
Autor:
Natasha Pinto Medici, Diana Martinez Saucedo, Danny Lee, Li-Ting Ku, Robert Tseng, Vincent Cannataro, Deanne Yugawa, Sumedha Chowdhury, Jeffrey Townsend, Christine A. Iacobuzio-Donahue, Omar Abdel-Wahab, Steven D. Leach, Luisa Escobar-Hoyos
Publikováno v:
Cancer Research. 82:A055-A055
With the aim to identify new second-hit mutations that cause pancreatic ductal adenocarcinoma (PDAC), other than mutations in p53, we performed a genetic interaction analysis based on the concept of mutually exclusive mutations, which suggests that m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7175fccf117159348bf6e4385511bac
https://doi.org/10.1158/1538-7445.panca22-a055
https://doi.org/10.1158/1538-7445.panca22-a055
Autor:
Jeffrey Townsend
Publikováno v:
Pour la Science. :44-52
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3649f03195f2929dc26f1f068f639ea7
https://doi.org/10.3917/pls.495.0044
https://doi.org/10.3917/pls.495.0044
Autor:
Jeffrey Townsend, Zheng Wang
Fungal Phylogenetics and Phylogenomics, Volume 100, the latest release in the Advances in Genetics series, presents users with new chapters that delve into such topics as the Advances of fungal phylogenomics and the impact on fungal systematics, Data
Autor:
Lloyd, Jeffrey Townsend
To better understand consequences of classical assumptions regarding deformation mechanisms at the mesoscale, experimental observations of mesoscale deformation are presented. In light of actual micrographics of deformed polycrystals, the Von Mises c
Externí odkaz:
http://hdl.handle.net/1853/34808
Autor:
Susan B. Altenbach, Connie Wainwright, Jeffrey Townsend, Karen W. Pearson, Anca Georgescu, Chiung-Chi Kuo, Lisa C. Staraci
Publikováno v:
Plant Molecular Biology. 18:235-245
We have increased the methionine content of the seed proteins of a commercial winter variety of canola by expressing a chimeric gene encoding a methionine-rich seed protein from Brazil nut in the seeds of transgenic plants. Transgenic canola seeds ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e515f47a7c6709dbcdd9a3e5c21e93f
https://doi.org/10.1007/bf00034952
https://doi.org/10.1007/bf00034952