Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Jeffrey T. Henderson"'
Autor:
Shudi Huang, Tyler R. Henderson, Chesarahmia Dojo Soeandy, Anastasiya Lezhanska, Jeffrey T. Henderson
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Efficient, facile gene modification of cells has become an indispensable part of modern molecular biology. For the majority of cell lines and several primary populations, such modifications can be readily performed through a variety of metho
Externí odkaz:
https://doaj.org/article/0d7862b5ead549d1923c6a4e90438c7e
Autor:
Abdulmottaleb E. Zetrini, Azhar Z. Abbasi, Chunsheng He, HoYin Lip, Ibrahim Alradwan, Andrew M. Rauth, Jeffrey T. Henderson, Xiao Yu Wu
Publikováno v:
Materials Today Bio, Vol 28, Iss , Pp 101206- (2024)
Radiotherapy (RT) is one of major therapeutic modalities in combating breast cancer. In RT, ionizing radiation is employed to induce DNA double-strand breaks (DSBs) as a primary mechanism that causes cancer cell death. However, the induced DNA damage
Externí odkaz:
https://doaj.org/article/a1dd332717db491980efe1b81f3e2f43
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Of all methods exercised in modern molecular biology, modification of cellular properties through the introduction or removal of nucleic acids is one of the most fundamental. As such, several methods have arisen to promote this process; thes
Externí odkaz:
https://doaj.org/article/87568a22fd7f44459752e89120d61dd8
Autor:
Alicia N Harracksingh, Julia Bandura, Takefumi Morizumi, Philippe P Monnier, Jeffrey T Henderson, Zhong-Ping Feng
Publikováno v:
PLoS ONE, Vol 19, Iss 11, p e0313407 (2024)
Optic photoreception is a critical function for animal survival. Across the evolutionary spectrum, diverse animal models have been used to investigate visual system function and potential mechanisms under physiological or pathophysiological states. H
Externí odkaz:
https://doaj.org/article/4502d70994b24ffda619c0842186fcde
Publikováno v:
Fluids and Barriers of the CNS, Vol 19, Iss 1, Pp 1-13 (2022)
Abstract Background Folates are a family of B9 vitamins that serve as one-carbon donors critical to biosynthetic processes required for the development and function of the central nervous system (CNS) in mammals. Folate transport is mediated by three
Externí odkaz:
https://doaj.org/article/61a2127ed0ea4b6eb0412d57b9ba1fa8
Autor:
Elliya Park, Lily Yi Li, Chunsheng He, Azhar Z. Abbasi, Taksim Ahmed, Warren D. Foltz, Regan O'Flaherty, Maham Zain, Robert P. Bonin, Andrew M. Rauth, Paul E. Fraser, Jeffrey T. Henderson, Xiao Yu Wu
Publikováno v:
Advanced Science, Vol 10, Iss 12, Pp n/a-n/a (2023)
Abstract Finding effective disease‐modifying treatment for Alzheimer's disease remains challenging due to an array of factors contributing to the loss of neural function. The current study demonstrates a new strategy, using multitargeted bioactive
Externí odkaz:
https://doaj.org/article/00664533c62e4fa0a99ec8433353bc08
Autor:
Abdulmottaleb E. Zetrini, HoYin Lip, Azhar Z. Abbasi, Ibrahim Alradwan, Taksim Ahmed, Chunsheng He, Jeffrey T. Henderson, Andrew M. Rauth, Xiao Yu Wu
Publikováno v:
Research, Vol 6 (2023)
Despite substantial progress in the treatment of castration-resistant prostate cancer (CRPC), including radiation therapy and immunotherapy alone or in combination, the response to treatment remains poor due to the hypoxic and immunosuppressive natur
Externí odkaz:
https://doaj.org/article/3768f06c7e5c44c0bc4140403e9cb270
Publikováno v:
Pharmaceutics, Vol 15, Iss 7, p 1857 (2023)
Maternal immune activation (MIA) during pregnancy is linked to neurodevelopmental disorders in humans. Similarly, the TLR7 agonist imiquimod alters neurodevelopment in rodents. While the mechanisms underlying MIA-mediated neurodevelopmental changes a
Externí odkaz:
https://doaj.org/article/5f1cafbd976c459c8bf29895ec8d3303
Publikováno v:
Pharmaceutics; Volume 15; Issue 7; Pages: 1857
Maternal immune activation (MIA) during pregnancy is linked to neurodevelopmental disorders in humans. Similarly, the TLR7 agonist imiquimod alters neurodevelopment in rodents. While the mechanisms underlying MIA-mediated neurodevelopmental changes a
Autor:
Joe Steinman, Andrea Ovcjak, Zhengwei Luo, Xinyang Zhang, Luiz Roberto Britto, Jeffrey T. Henderson, Hong-Shuo Sun, Zhong-Ping Feng
Publikováno v:
Advanced Neurology. 1:1-18
Transient receptor potential melastatin 2 (TRPM2) is a calcium-permeable ion channel implicated in neurodegenerative disorders and conditions. It is activated in response to reactive oxygen species (ROS) and thereby alters Ca2+ homeostasis and initia