Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Jeffrey T, Wigle"'
Autor:
Ryan F. Leung, Ankita M. George, Enola M. Roussel, Maree C. Faux, Jeffrey T. Wigle, David D. Eisenstat
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Forebrain development in vertebrates is regulated by transcription factors encoded by homeobox, bHLH and forkhead gene families throughout the progressive and overlapping stages of neural induction and patterning, regional specification and generatio
Externí odkaz:
https://doaj.org/article/a2ab1209f1f84256818f9f22cae93f25
Autor:
Peter Zahradka, Carla G. Taylor, Leslee Tworek, Raissa Perrault, Sofia M’Seffar, Megha Murali, Tara Loader, Jeffrey T. Wigle
Publikováno v:
Biomolecules, Vol 13, Iss 1, p 30 (2022)
A decrease in the circulating levels of adiponectin in obesity increases the risk of metabolic complications, but the role of globular adiponectin, a truncated form produced by proteolytic cleavage, has not been defined. The objective of this investi
Externí odkaz:
https://doaj.org/article/e1a0cedcb9bc4de8ba833307be4ef5e9
Publikováno v:
Cells, Vol 11, Iss 16, p 2478 (2022)
Endothelial cells regulate vascular homeostasis through the secretion of various paracrine molecules, including bioactive lipids, but little is known regarding the enzymes responsible for generating these lipids under either physiological or pathophy
Externí odkaz:
https://doaj.org/article/040463328f8743408458577a2906bb8c
Autor:
Raghu S Nagalingam, Sikta Chattopadhyaya, Danah S Al-Hattab, David Y C Cheung, Leah Y Schwartz, Sayantan Jana, Nina Aroutiounova, D Allison Ledingham, Teri L Moffatt, Natalie M Landry, Rushita A Bagchi, Ian M C Dixon, Jeffrey T Wigle, Gavin Y Oudit, Zamaneh Kassiri, Davinder S Jassal, Michael P Czubryt
Publikováno v:
European Heart Journal. 43:4739-4750
Aims In response to pro-fibrotic signals, scleraxis regulates cardiac fibroblast activation in vitro via transcriptional control of key fibrosis genes such as collagen and fibronectin; however, its role in vivo is unknown. The present study assessed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a3e1676f5ff089c0cab8c5222b495a4
https://doi.org/10.1093/eurheartj/ehac362
https://doi.org/10.1093/eurheartj/ehac362
Autor:
Jeffrey T. Wigle, David D. Eisenstat
Publikováno v:
Neurodevelopmental Pediatrics ISBN: 9783031207914
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54c7d5188e12ca5ddf52a1efcdda3dc5
https://doi.org/10.1007/978-3-031-20792-1_2
https://doi.org/10.1007/978-3-031-20792-1_2
Autor:
Xavier Lieben Louis, Zach Meikle, Laura Chan, Garret DeGagne, Rebecca Cummer, Shannon Meikle, Sampath Krishnan, Liping Yu, Thomas Netticadan, Jeffrey T. Wigle
Publikováno v:
Molecules, Vol 24, Iss 14, p 2604 (2019)
In this study, we tested the potential cardioprotective effects of the phytoalexin resveratrol (Rsv) on primary adult rat cardiac fibroblasts (CF), myofibroblasts (MF) and cardiomyocytes. Adult rat CF and cardiomyocytes were isolated from male 10-wee
Externí odkaz:
https://doaj.org/article/bab036931e0345db8b19c2ba382b3eb9
Autor:
Ryan F. Leung, Ankita M. George, Enola M. Roussel, Maree C. Faux, Jeffrey T. Wigle, David D. Eisenstat
Publikováno v:
Frontiers in neuroscience. 16
Forebrain development in vertebrates is regulated by transcription factors encoded by homeobox, bHLH and forkhead gene families throughout the progressive and overlapping stages of neural induction and patterning, regional specification and generatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c691ac867b00ff5a67f614a429bce7fe
https://pubmed.ncbi.nlm.nih.gov/35546872
https://pubmed.ncbi.nlm.nih.gov/35546872
Publikováno v:
Molecules
Molecules, Vol 26, Iss 6600, p 6600 (2021)
Molecules, Vol 26, Iss 6600, p 6600 (2021)
Atherosclerosis, myocardial infarction (MI) and heart failure (HF) are the main causes of mortality and morbidity around the globe. New therapies are needed to better manage ischemic heart disease and HF as existing strategies are not curative. Resve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::745d081cafa7ba9dbe1cfa606adcaaa7
http://europepmc.org/articles/PMC8587649
http://europepmc.org/articles/PMC8587649
Autor:
Liping Yu, Jeffrey T. Wigle, Shelley Zieroth, Thomas Netticadan, Karen Sayfee, Mihir Parikh, Pema Raj
Publikováno v:
Molecules
Volume 26
Issue 16
Molecules, Vol 26, Iss 5006, p 5006 (2021)
Volume 26
Issue 16
Molecules, Vol 26, Iss 5006, p 5006 (2021)
The development and progression of heart failure (HF) due to myocardial infarction (MI) is a major concern even with current optimal therapy. Resveratrol is a plant polyphenol with cardioprotective properties. Sacubitril/valsartan is known to be bene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcaf0acb148321b63c1664372983b50b
https://pubmed.ncbi.nlm.nih.gov/34443591
https://pubmed.ncbi.nlm.nih.gov/34443591
Autor:
Xavier Lieben Louis, Shannel E. Susser, Zach Meikle, Todd A. Duhamel, Shayla MacInnis, Liping Yu, Thomas Netticadan, Pema Raj, Jeffrey T. Wigle
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 97:1132-1140
Long-chain saturated fatty acids, especially palmitic acid (PA), contribute to cardiomyocyte lipotoxicity. This study tests the effects of PA on adult rat cardiomyocyte contractile function and proteins associated with calcium regulating cardiomyocyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba4bd4825cb6653cb53b740bf074442e
https://doi.org/10.1139/cjpp-2019-0051
https://doi.org/10.1139/cjpp-2019-0051