Zobrazeno 1 - 10
of 207
pro vyhledávání: '"Jeffrey T, Borenstein"'
Autor:
Ashley L. Gard, Rebeccah J. Luu, Ryan Maloney, Madeline H. Cooper, Brian P. Cain, Hesham Azizgolshani, Brett C. Isenberg, Jeffrey T. Borenstein, Jane Ong, Joseph L. Charest, Else M. Vedula
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Microfluidic model of human gingival tissue with complex oral tissue architecture allows monthlong phenotypic expression, response and recovery to multiple inflammatory triggers and the potential for identification of new therapeutic targets for gum
Externí odkaz:
https://doaj.org/article/5540568cb3774a98a700f0802b6d3f31
Autor:
Brett C. Isenberg, Else M. Vedula, Jose Santos, Diana J. Lewis, Teryn R. Roberts, George Harea, David Sutherland, Beau Landis, Samuel Blumenstiel, Joseph Urban, Daniel Lang, Bryan Teece, WeiXuan Lai, Rose Keating, Diana Chiang, Andriy I. Batchinsky, Jeffrey T. Borenstein
Publikováno v:
Advanced Science, Vol 10, Iss 18, Pp n/a-n/a (2023)
Abstract Recent global events such as COVID‐19 pandemic amid rising rates of chronic lung diseases highlight the need for safer, simpler, and more available treatments for respiratory failure, with increasing interest in extracorporeal membrane oxy
Externí odkaz:
https://doaj.org/article/9f932182866646569733d30de52de141
Autor:
Christine R. Fisher, Felix Mba Medie, Rebeccah J. Luu, Robert B. Gaibler, Thomas J. Mulhern, Caitlin R. Miller, Chelsea J. Zhang, Logan D. Rubio, Elizabeth E. Marr, Vidhya Vijayakumar, Elizabeth P. Gabriel, Landys Lopez Quezada, Chun-Hui Zhang, Karen S. Anderson, William L. Jorgensen, Jehan W. Alladina, Benjamin D. Medoff, Jeffrey T. Borenstein, Ashley L. Gard
Publikováno v:
Cells, Vol 12, Iss 22, p 2639 (2023)
COVID-19 emerged as a worldwide pandemic in early 2020, and while the rapid development of safe and efficacious vaccines stands as an extraordinary achievement, the identification of effective therapeutics has been less successful. This process has b
Externí odkaz:
https://doaj.org/article/8d7df97e30ef466cac3feb43edd18767
Autor:
Miles T. Rogers, Ashley L. Gard, Robert Gaibler, Thomas J. Mulhern, Rivka Strelnikov, Hesham Azizgolshani, Brian P. Cain, Brett C. Isenberg, Nerses J. Haroutunian, Nicole E. Raustad, Philip M. Keegan, Matthew P. Lech, Lindsay Tomlinson, Jeffrey T. Borenstein, Joseph L. Charest, Corin Williams
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Microphysiological organ-on-chip models offer the potential to improve the prediction of drug safety and efficacy through recapitulation of human physiological responses. The importance of including multiple cell types within tissue models h
Externí odkaz:
https://doaj.org/article/8cf0ffca17424706a726f4770e2e96bd
Publikováno v:
Frontiers in Medical Technology, Vol 3 (2021)
Microfluidic systems for the analysis of tissue models of cancer and other diseases are rapidly emerging, with an increasing recognition that perfusion is required to recapitulate critical aspects of the in vivo microenvironment. Here we report on th
Externí odkaz:
https://doaj.org/article/e206f2bb3ba6417494c6197946c6f684
Autor:
Jose Santos, Else M. Vedula, Weixuan Lai, Brett C. Isenberg, Diana J. Lewis, Dan Lang, David Sutherland, Teryn R. Roberts, George T. Harea, Christian Wells, Bryan Teece, Paramesh Karandikar, Joseph Urban, Thomas Risoleo, Alla Gimbel, Derek Solt, Sahar Leazer, Kevin K. Chung, Sivaprasad Sukavaneshvar, Andriy I. Batchinsky, Jeffrey T. Borenstein
Publikováno v:
Micromachines, Vol 12, Iss 8, p 888 (2021)
The recent emergence of microfluidic extracorporeal lung support technologies presents an opportunity to achieve high gas transfer efficiency and improved hemocompatibility relative to the current standard of care in extracorporeal membrane oxygenati
Externí odkaz:
https://doaj.org/article/94eae3f1f02741478069e5b638c41d62
Autor:
Shuo Xiao, Jonathan R. Coppeta, Hunter B. Rogers, Brett C. Isenberg, Jie Zhu, Susan A. Olalekan, Kelly E. McKinnon, Danijela Dokic, Alexandra S. Rashedi, Daniel J. Haisenleder, Saurabh S. Malpani, Chanel A. Arnold-Murray, Kuanwei Chen, Mingyang Jiang, Lu Bai, Catherine T. Nguyen, Jiyang Zhang, Monica M. Laronda, Thomas J. Hope, Kruti P. Maniar, Mary Ellen Pavone, Michael J. Avram, Elizabeth C. Sefton, Spiro Getsios, Joanna E. Burdette, J. Julie Kim, Jeffrey T. Borenstein, Teresa K. Woodruff
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
The female reproductive tract constitutes the ovary, fallopian tubes, uterus, and cervix, but it is challenging to engineer this systemin vitro. Here, the authors develop a microfluidic device (EVATAR) with reproductive tract and peripheral tissues t
Externí odkaz:
https://doaj.org/article/502594c466a14109b2eb6d7e22593a42
Autor:
Todd L. Astor, Jeffrey T. Borenstein
Publikováno v:
Artificial Organs. 46:1227-1239
The increasing prevalence of chronic lung disease worldwide, combined with the emergence of multiple pandemics arising from respiratory viruses over the past century, highlights the need for safer and efficacious means for providing artificial lung s
Publikováno v:
Materials Today. 54:27-41
Autor:
Else M. Vedula, Brett C. Isenberg, Jose Santos, WeiXuan Lai, Diana J. Lewis, David Sutherland, Teryn R. Roberts, George T. Harea, Christian Wells, Bryan Teece, Joseph Urban, Thomas Risoleo, Derek Solt, Sahar Leazer, Kevin Chung, Sivaprasad Sukavaneshvar, Andriy I. Batchinsky, Jeffrey T. Borenstein
Publikováno v:
ASAIO journal (American Society for Artificial Internal Organs : 1992). 68(10)
Extracorporeal membrane oxygenation (ECMO) has been advancing rapidly due to a combination of rising rates of acute and chronic lung diseases as well as significant improvements in the safety and efficacy of this therapeutic modality. However, the co