Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jeffrey Sum-Lung Wong"'
Autor:
Vikki Tang, Jeffrey Sum Lung Wong, Gerry Gin Wai Kwok, Bryan Cho Wing Li, Ka Wing Ma, Wong Hoi She, Chung Mau Lo
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 2 (2021)
Background Programmed cell death protein 1 (PD-1) pathway blockade with immune checkpoint inhibitors (ICIs) is a standard therapy in advanced hepatocellular carcinoma (HCC) nowadays. No strategies to overcome ICI resistance have been described. We ai
Externí odkaz:
https://doaj.org/article/5f87dbb432394523851e4b34b6953f4a
Autor:
Tsun-Ho LAM, Jeffrey Sum-Lung WONG, Chun-Ka WONG, Gerry Gin Wai KWOK, Miaochang ZHOU, Benjamin Yu-Fai SO, Ian Yu-Hin LEUNG, Hung-Fat TSE
Publikováno v:
Journal of the Hong Kong College of Cardiology. 29:135-142
Publikováno v:
Hepatology Communications. 7
Autor:
Hiroto Kikuchi, Aya Matsui, Satoru Morita, Zohreh Amoozgar, Koetsu Inoue, Zhiping Ruan, Daniel Staiculescu, Jeffrey Sum-Lung Wong, Peigen Huang, Thomas Yau, Rakesh K Jain, Dan G Duda
Publikováno v:
J Natl Cancer Inst
Immune checkpoint blockade combined with antiangiogenic therapy induces vascular normalization and antitumor immunity and is efficacious in hepatocellular carcinoma (HCC); but whether and how initial immunotherapy affects the efficacy of subsequent a
Autor:
Tracy Cy Shum, Yawen Dong, Thomas W. Leung, Wong Hoi She, Bryan Cho Wing Li, Vikki Tang, Cynthia S Y Yeung, Thomas Yau, Jeffrey Sum Lung Wong, Gerry Gin-Wai Kwok, Josephine Tsang, Ka Wing Ma, Ada Law, Anna Tai, Joanne Chiu, Tan To Cheung, Roland Leung
Publikováno v:
Cancers
Volume 13
Issue 9
Cancers, Vol 13, Iss 2002, p 2002 (2021)
Volume 13
Issue 9
Cancers, Vol 13, Iss 2002, p 2002 (2021)
Simple Summary The vascular endothelial growth factor and c-MET pathways are strongly implicated in hepatocellular carcinoma (HCC). Cabozantinib inhibits both pathways and has been approved in sorafenib-exposed advanced HCC (aHCC). We aimed to evalua
Autor:
Roland Leung, Thomas Yau, Jeffrey Sum Lung Wong, Tan To Cheung, Joanne Chiu, Bryan Cho Wing Li, Josephine Tsang, Gerry Gin Wai Kwok
Publikováno v:
Expert review of gastroenterologyhepatology. 15(6)
The systemic treatment of advanced, unresectable hepatocellular carcinoma (HCC) has undergone an evolution in recent years. In March 2020, a combination of nivolumab and ipilimumab was approved by the FDA for treatment of patients with advanced HCC w
Autor:
Yawen Dong, Tan To Cheung, Ada Law, Ka Wing Ma, Vikki Tang, Tracy Cy Shum, Roland Leung, Gin Wai Kwok, W.H. She, Thomas W.T. Leung, Anna Tai, Jeffrey Sum Lung Wong, Cynthia S Y Yeung, Joanne Wing Yan Chiu, Thomas Yau, Bryan Li, Wing Yan Josephine Tsang
Publikováno v:
Journal of Clinical Oncology. 39:e16179-e16179
e16179 Background: Cabozantinib is licensed for use as second- or third-line treatment for sorafenib-exposed advanced hepatocellular carcinoma (aHCC) based on the phase III CELESTIAL trial. However, its use in the post-immune checkpoint inhibitors (I
Autor:
Jess L.C. Chan, Tan To Cheung, Gin Wai Kwok, Jeffrey Sum Lung Wong, Wai Meng David Tai, Joycelyn Jie Xin Lee, Su Pin Choo, Joanne Wing Yan Chiu, Thomas Yau, Bryan Li, Vikki Tang, Roland Leung, Wing Yan Josephine Tsang
Publikováno v:
Journal of Clinical Oncology. 39:e16181-e16181
e16181 Background: Immune checkpoint inhibitors (ICIs) and tyrosine kinase inhibitors (TKIs) are widely adopted in contemporary advanced HCC (aHCC) treatment algorithms. Nevertheless, the optimal strategy for treatment after ICI exposure is unknown.
Autor:
Wing Yan Josephine Tsang, Gin Wai Kwok, Thomas Yau, Bryan Li, Tan To Cheung, Ka Wing Ma, Jeffrey Sum Lung Wong, W.H. She, Vikki Tang, Roland Leung, Joanne Wing Yan Chiu
Publikováno v:
Journal of Clinical Oncology. 39:e16184-e16184
e16184 Background: Hepatic derangement commonly accompanies advanced HCC (aHCC) and limits the use of systemic therapies. We aimed to evaluate the use of single agent anti-PD-1 nivolumab or pembrolizumab in Child-Pugh (CP) grade B or C patients with
Autor:
Ryohichi Sugimura, Jeffrey Sum Lung Wong, Thomas Yau, Roland Leung, Joanne Wing Yan Chiu, Yawen Dong, Bryan Cho Wing Li, Tan To Cheung, Gerry Gin Wai Kwok, Ka-On Lam
Publikováno v:
Cancers, Vol 13, Iss 1949, p 1949 (2021)
Cancers
Cancers
Simple Summary Hepatocellular carcinoma is an aggressive cancer with high mortality. The introduction of immune-checkpoint inhibitors (ICIs) targeting the programmed-cell death 1 pathway (PD-1/L1) has led to a paradigmatic change in the systemic trea