Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jeffrey Spraggins"'
Autor:
André Kleinridders, Heather A. Ferris, Michelle L. Reyzer, Michaela Rath, Marion Soto, M. Lisa Manier, Jeffrey Spraggins, Zhihong Yang, Robert C. Stanton, Richard M. Caprioli, C. Ronald Kahn
Publikováno v:
Molecular Metabolism, Vol 12, Iss , Pp 113-121 (2018)
Objective: Glucose is the major energy substrate of the brain and crucial for normal brain function. In diabetes, the brain is subject to episodes of hypo- and hyperglycemia resulting in acute outcomes ranging from confusion to seizures, while chroni
Externí odkaz:
https://doaj.org/article/e3b3bf9b3ec147769c0344d2c9e1cbb6
Scope: To describe the procedure for spraying tissue sections with CHCA for lipids. CHCA is used as a safer matrix to ship coated slides to collaborators. Expected Outcome: Slides should be coated with CHCA. Tissue sections should be imaged within 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50b5230c0fba2ae7b45dc21234ea041b
https://doi.org/10.17504/protocols.io.ewov1o3xylr2/v1
https://doi.org/10.17504/protocols.io.ewov1o3xylr2/v1
Scope: To provide a method for removal of MALDI matrix, fixation and preparation of tissue sections for Cell DIVE.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d828951c2d5a08fd2213928ae98d4e26
https://doi.org/10.17504/protocols.io.4r3l276d3g1y/v1
https://doi.org/10.17504/protocols.io.4r3l276d3g1y/v1
Autor:
Katerina Djambazova, Martin Dufresne, Lukasz Migas, Angela Kruse, Raf Van de Plas, Richard Caprioli, Jeffrey Spraggins
Gangliosides are classified as acidic glycosphingolipids, containing ceramide moieties and oligosaccharide chains with one or multiple sialic acid residue(s). The presence of multiple sialylation sites gives rise to highly diverse isomeric structures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40cefc0efbe7894a0488c2d86a0b4b44
https://doi.org/10.26434/chemrxiv-2021-tkzc6
https://doi.org/10.26434/chemrxiv-2021-tkzc6
Molecular Mapping of Neutral Lipids using Silicon Nanopost Arrays and TIMS Imaging Mass Spectrometry
Autor:
Jarod Fincher, Katerina Djambazova, Dustin R. Klein, Martin Dufresne, Lukasz Migas, Raf Van de Plas, Richard Caprioli, Jeffrey Spraggins
Our work demonstrates the ability to perform high spatial resolution imaging mass spectrometry (IMS) using silicon nanopost arrays (NAPA), a matrix-free laser desorption ionization (LDI) substrate, for multiple classes of neutral lipids from biologic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a6b9e11d7a349a3e8953d072c4c6447
https://doi.org/10.26434/chemrxiv.14216963.v1
https://doi.org/10.26434/chemrxiv.14216963.v1
Autor:
Richard M. Caprioli, Jeffrey Spraggins, Audra M. Judd, Danielle B. Gutierrez, Josiah McMillen
Matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI IMS) allows for highly multiplexed, unlabeled mapping of analytes from tissue sections. However, further work is needed to improve sensitivity and depth of coverage for prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9e3133056e510250fd8ad56569c0d93
https://doi.org/10.26434/chemrxiv.13483302.v2
https://doi.org/10.26434/chemrxiv.13483302.v2
Tryptic Peptide Signal Enhancement via MALDI IMS Post-ionization (MALDI-2) from Thin Tissue Sections
Autor:
Josiah McMillen, Danielle B. Gutierrez, Audra M. Judd, Jeffrey Spraggins, Richard M. Caprioli
Matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI IMS) allows for the highly multiplexed, unlabeled mapping of analytes from thin tissue sections but further work is needed to improve sensitivity and depth of coverage for p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24c21d6b37422fb583485e9036c734e2
https://doi.org/10.26434/chemrxiv.13483302.v1
https://doi.org/10.26434/chemrxiv.13483302.v1
Matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI IMS) allows for highly multiplexed, untargeted detection of many hundreds of analytes from tissue. Recently, laser post-ionization (MALDI-2) has been developed for increased
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95c944441e51feb3c9042ca8c1863433
https://doi.org/10.26434/chemrxiv.12494705.v1
https://doi.org/10.26434/chemrxiv.12494705.v1
Autor:
Jeffrey Spraggins, Richard M. Caprioli, Raf Van de Plas, Emilio Rivera, Elizabeth Neumann, Lukasz Migas, Dustin R. Klein, Katerina Djambazova
Lipids are a structurally diverse class of molecules with important biological functions including cellular signaling and energy storage. Matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) allows for direct map-ping o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67196c9cb69fbaa7f0d685aaab769acf
https://doi.org/10.26434/chemrxiv.12331652.v2
https://doi.org/10.26434/chemrxiv.12331652.v2
Autor:
Katerina Djambazova, Dustin R. Klein, Lukasz Migas, Elizabeth Neumann, Emilio Rivera, Raf Van de Plas, Richard M. Caprioli, Jeffrey Spraggins
Lipids are a structurally diverse class of molecules, with important biological functions including cellular signaling and energy storage. Matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) allows for visualization of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e4650c0da14099862f02330af379178
https://doi.org/10.26434/chemrxiv.12331652.v1
https://doi.org/10.26434/chemrxiv.12331652.v1