Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Jeffrey S. Willey"'
Autor:
Samuel Rosas, Andy Kwok, Joseph Moore, Lihong Shi, Thomas L. Smith, E. Ann Tallant, Bethany A. Kerr, Jeffrey S. Willey
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 6014 (2024)
Osteoarthritis (OA) is increasing worldwide, and previous work found that OA increases systemic cartilage oligomeric matrix protein (COMP), which has also been implicated in prostate cancer (PCa). As such, we sought to investigate whether OA augments
Externí odkaz:
https://doaj.org/article/adfb5d5c4a3a4e27ab29225c0c96bf8b
Autor:
Jacob Raber, Sarah Holden, Kat Kessler, Breanna Glaeser, Chloe McQuesten, Mitali Chaudhari, Fiona Stenzel, Marek Lenarczyk, Scott Willem Leonard, Jeffrey Morré, Jaewoo Choi, Amy Kronenberg, Alexander Borg, Andy Kwok, Jan Frederik Stevens, Christopher Olsen, Jeffrey S. Willey, Gerd Bobe, Jessica Minnier, John E. Baker
Publikováno v:
Frontiers in Physiology, Vol 14 (2024)
Introduction: The space environment astronauts experience during space missions consists of multiple environmental challenges, including microgravity. In this study, we assessed the behavioral and cognitive performances of male Fisher rats 2 months a
Externí odkaz:
https://doaj.org/article/1bb6f8739e9d45ff9ac8c715fc29053f
Characterization of gene expression profiles in the mouse brain after 35 days of spaceflight mission
Autor:
Jacob M. Holley, Seta Stanbouly, Michael J. Pecaut, Jeffrey S. Willey, Michael Delp, Xiao Wen Mao
Publikováno v:
npj Microgravity, Vol 8, Iss 1, Pp 1-10 (2022)
Abstract It has been proposed that neuroinflammatory response plays an important role in the neurovascular remodeling in the brain after stress. The goal of the present study was to characterize changes in the gene expression profiles associated with
Externí odkaz:
https://doaj.org/article/fc38a452cfec4318834d8572d8d3e102
Autor:
Jeffrey S. Willey, Serena Aunon-Chancellor, Lauren A. Miles, Joseph E. Moore, Xiao W. Mao, Robert W. Wallace, Matthew C. Foy
Publikováno v:
npj Microgravity, Vol 8, Iss 1, Pp 1-3 (2022)
Abstract Alpha(α)Klotho, a soluble transmembrane protein, facilitates calcium-phosphorus homeostasis through feedback between bone and kidney and is a potential systemic biomarker for bone-kidney health during spaceflight. We determined if: (1) plas
Externí odkaz:
https://doaj.org/article/41dd8fe159e248759815a4acb2bfd279
Autor:
Andy T. Kwok, Nequesha S. Mohamed, Johannes F. Plate, Raghunatha R. Yammani, Samuel Rosas, Ted A. Bateman, Eric Livingston, Joseph E. Moore, Bethany A. Kerr, Jingyun Lee, Cristina M. Furdui, Li Tan, Mary L. Bouxsein, Virginia L. Ferguson, Louis S. Stodieck, David C. Zawieja, Michael D. Delp, Xiao W. Mao, Jeffrey S. Willey
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Reduced knee weight-bearing from prescription or sedentary lifestyles are associated with cartilage degradation; effects on the meniscus are unclear. Rodents exposed to spaceflight or hind limb unloading (HLU) represent unique opportunities
Externí odkaz:
https://doaj.org/article/e20ccc74580a4e1287b71ce54f1f7858
Autor:
Jacob Raber, Sarah Holden, Reetesh Sudhakar, Reed Hall, Breanna Glaeser, Marek Lenarczyk, Kristen Rockwell, Natalie Nawarawong, Jennifer Sterrett, Ruby Perez, Scott William Leonard, Jeffrey Morré, Jaewoo Choi, Amy Kronenberg, Alexander Borg, Andy Kwok, Jan Frederik Stevens, Christopher M. Olsen, Jeffrey S. Willey, Gerd Bobe, John Baker
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
A limitation of simulated space radiation studies is that radiation exposure is not the only environmental challenge astronauts face during missions. Therefore, we characterized behavioral and cognitive performance of male WAG/Rij rats 3 months after
Externí odkaz:
https://doaj.org/article/0574366066554b75894e103ed10b7df6
Autor:
Michael K. Farris, Corbin A. Helis, Ryan T. Hughes, Michael C. LeCompte, Alexander M. Borg, Karina Nieto, Michael T. Munley, Jeffrey S. Willey
Publikováno v:
Cancers, Vol 12, Iss 2, p 427 (2020)
Ionizing radiation is a critical aspect of current cancer therapy. While classically mature bone was thought to be relatively radio-resistant, more recent data have shown this to not be the case. Radiation therapy (RT)-induced bone loss leading to fr
Externí odkaz:
https://doaj.org/article/73852d9c31c34ce1bf7fef9d15ee0feb
Autor:
Daniel N. Bracey, Thorsten M. Seyler, Alexander H. Jinnah, Mark O. Lively, Jeffrey S. Willey, Thomas L. Smith, Mark E. Van Dyke, Patrick W. Whitlock
Publikováno v:
Journal of Functional Biomaterials, Vol 9, Iss 3, p 45 (2018)
Background: Bone grafts are used in approximately one half of all musculoskeletal surgeries. Autograft bone is the historic gold standard but is limited in supply and its harvest imparts significant morbidity to the patient. Alternative sources of bo
Externí odkaz:
https://doaj.org/article/1aada6af6d63445fb5ca8d05f5c71a0c
Autor:
Wayne D. Newhauser, Jacqueline P. Williams, Michael A. Noska, Caridad Borrás, E. Vincent Holahan, Shaheen A. Dewji, Thomas E. Johnson, Jerry W. Hiatt, John W. Poston, Nolan Hertel, Dustin A. Gress, Michael D. Mills, David W. Jordan, Steven G. Sutlief, Melissa C. Martin, Edward Jackson, Edward I. Bluth, Donald P. Frush, M. Elizabeth Oates, Jeanne LaBerge, Hubert Y. Pan, Seth A. Rosenthal, Lawrence W. Townsend, Lori Brady, Janice Lindegard, Howard L. Hall, Elizabeth McAndrew‐Benavides, Eric Abelquist, Mitchell S. Anscher, Marcelo Vazquez, Amy Kronenberg, Jeffrey S. Willey, Theodore Lawrence, Gayle E. Woloschak, Brian Marples, Rosemary Wong, Michael Story, Roger W. Howell, Tom K. Hei, Sergey Y. Tolmachev, John D. Auxier, Thomas L. Rucker, Mikael Nilsson, Ralf Sudowe, Brian A. Powell, Mark P. Jensen
Publikováno v:
Journal of Applied Clinical Medical Physics. 23
Autor:
Wayne D. Newhauser, Jacqueline P. Williams, Michael A. Noska, Caridad Borrás, E. Vincent Holahan, Shaheen A. Dewji, Thomas E. Johnson, Jerry W. Hiatt, John W. Poston, Nolan Hertel, Dustin A. Gress, Michael D. Mills, David W. Jordan, Steven G. Sutlief, Melissa C. Martin, Edward Jackson, Edward I. Bluth, Donald P. Frush, M. Elizabeth Oates, Jeanne LaBerge, Hubert Y. Pan, Seth A. Rosenthal, Lawrence W. Townsend, Lori Brady, Janice Lindegard, Howard L. Hall, Elizabeth McAndrew‐Benavides, Eric Abelquist, Mitchell S. Anscher, Marcelo Vazquez, Amy Kronenberg, Jeffrey S. Willey, Theodore Lawrence, Gayle E. Woloschak, Brian Marples, Rosemary Wong, Michael Story, Roger W. Howell, Tom K. Hei, Sergey Y. Tolmachev, John D. Auxier, Thomas L. Rucker, Mikael Nilsson, Ralf Sudowe, Brian A. Powell, Mark P. Jensen
Publikováno v:
Journal of Applied Clinical Medical Physics. 23