Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jeffrey S. Taylor"'
Publikováno v:
Healthcare financial management : journal of the Healthcare Financial Management Association. 70(11)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2eadc59780f1ed4abfd33558b849589e
https://pubmed.ncbi.nlm.nih.gov/29897221
https://pubmed.ncbi.nlm.nih.gov/29897221
Autor:
Terrence M. Ciccarone, Hans E. Huber, Samuel L. Graham, Ronald G. Robinson, Jeffrey S. Taylor, Lorena S. Beese, Michelle Ellis-Hutchings, Robert B. Lobell, Nancy E. Kohl, Anthony W. Shaw, Eileen S. Walsh, Nancy N. Tsou, Desolms S Jane, Christine Fernandes, Suzanne C. Mactough, Kelly Hamilton, Carolyn A. Buser
Publikováno v:
Journal of Medicinal Chemistry. 46:2973-2984
A series of novel diaryl ether lactams have been identified as very potent dual inhibitors of protein farnesyltransferase (FTase) and protein geranylgeranyltransferase I (GGTase-I), enzymes involved in the prenylation of Ras. The structure of the com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7157b39100cc527794d744d80896dbd
https://doi.org/10.1021/jm020587n
https://doi.org/10.1021/jm020587n
Publikováno v:
Proceedings of the National Academy of Sciences. 100:3895-3900
DNA polymerases replicate DNA by adding nucleotides to a growing primer strand while avoiding frameshift and point mutations. Here we present a series of up to six successive replication events that were obtained by extension of a primed template dir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69d2637e3d8927041520e22577b3c03f
https://doi.org/10.1073/pnas.0630532100
https://doi.org/10.1073/pnas.0630532100
Autor:
Kelly Hamilton, Michael J. Bogusky, Robert B. Lobell, Lorena S. Beese, Joel R. Huff, Samuel L. Graham, Marc Abrams, Jackson B. Gibbs, Christine Fernandes, Ronald G. Robinson, J. Christopher Culberson, Carl F. Homnick, Eileen S. Walsh, Joseph J. Lynch, David C. Heimbrook, Michelle Ellis-Hutchings, Douglas C. Beshore, Hans E. Huber, Kenneth S. Koblan, Jeffrey S. Taylor, George D. Hartman, Hema Bhimnathwala, Kelem Kassahun, Nancy E. Kohl, Theresa M. Williams, Carolyn A. Buser, A. David Rodrigues, Joseph P. Davide, C. Blair Zartman, Steven N. Gallicchio, Ian M. Bell
Publikováno v:
Journal of Medicinal Chemistry. 45:2388-2409
A series of macrocyclic 3-aminopyrrolidinone farnesyltransferase inhibitors (FTIs) has been synthesized. Compared with previously described linear 3-aminopyrrolidinone FTIs such as compound 1, macrocycles such as 49 combined improved pharmacokinetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4654ba1a8f496a6a73493cd839fe1d14
https://doi.org/10.1021/jm010531d
https://doi.org/10.1021/jm010531d
Autor:
Jeffrey S. Taylor
Publikováno v:
Pediatric Surgery ISBN: 9783319043395
Idiopathic thrombocytopenic purpura (ITP) is marked by thrombocytopenia (often profound) occurring due to destruction of antibody sensitized platelets by the reticuloendothelial system (RES).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94bc54a8c967e525f117cb387d6e6019
https://doi.org/10.1007/978-3-319-04340-1_53
https://doi.org/10.1007/978-3-319-04340-1_53
Autor:
Jeffrey S. Taylor
Publikováno v:
Pediatric Surgery ISBN: 9783319043395
Thrombotic Thrombocytopenic Purpura (TTP) is a syndrome marked by waxing and waning episodes of organ and tissue ischemia secondary to reversible platelet aggregation in the microvasculature. It often presents with thrombocytopenia, microangiopathic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd1c7e7708a0a2f7fa45597011bde08b
https://doi.org/10.1007/978-3-319-04340-1_54
https://doi.org/10.1007/978-3-319-04340-1_54
Autor:
Jeffrey S. Taylor
Publikováno v:
Pediatric Surgery ISBN: 9783319043395
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c97072e11b236205309ef1192be3e2eb
https://doi.org/10.1007/978-3-319-04340-1_52
https://doi.org/10.1007/978-3-319-04340-1_52
Autor:
Jeffrey S. Taylor
Publikováno v:
Pediatric Surgery ISBN: 9783319043395
Sickle cell anemia is one of the first diseases understood at the molecular level. Valine substituted for glutamic acid in the beta globin subunit leads to decreased solubility in the de-oxygenated state. It may partially protect infants from cerebra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::012b85287479b93b8563752e6a8fd168
https://doi.org/10.1007/978-3-319-04340-1_55
https://doi.org/10.1007/978-3-319-04340-1_55
Autor:
Jeffrey S. Taylor, Roger M. Burnett
Publikováno v:
Proteins: Structure, Function, and Genetics. 41:173-191
A new program named "DARWIN" has been developed to perform docking calculations with proteins and other biological molecules. The program uses the Genetic Algorithm to optimize the molecule's conformation and orientation under the selective pressure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a55c87c026abd191007f14a1d46062b
https://doi.org/10.1002/1097-0134(20001101)41:2<173::aid-prot30>3.0.co
https://doi.org/10.1002/1097-0134(20001101)41:2<173::aid-prot30>3.0.co
Autor:
Robert E, Brown, Dongfeng, Tan, Jeffrey S, Taylor, Michal, Miller, Jeffrey W, Prichard, Marylee M, Kott
Publikováno v:
Annals of clinical and laboratory science. 37(2)
Morphoproteomic analysis reveals the constitutive activation of the mTOR, ERK, and NF-kappaB pathways in high risk neuroblastoma (HRN) cases as evidenced by (a) collective commonalities of: phosphorylated (p)-mTOR, p70S6K, ERK 1/2, and NF-kappaBp65 p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e7c4905f00efc598292fb335bdfde2d4
https://pubmed.ncbi.nlm.nih.gov/17522369
https://pubmed.ncbi.nlm.nih.gov/17522369