Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Jeffrey S. Simske"'
Publikováno v:
Physiological Reports, Vol 5, Iss 23, Pp n/a-n/a (2017)
Abstract The renal podocyte is central to the filtration function of the kidney that is dependent on maintaining both highly organized, branched cell structures forming foot processes, and a unique cell‐cell junction, the slit diaphragm. Our recent
Externí odkaz:
https://doaj.org/article/17f2aa83c96f40ffb8aa77b57b2c39c8
Autor:
Yi Dong, Jeffrey S. Simske
Publikováno v:
Developmental Dynamics. 245:653-666
BACKGROUND TMEM47 is the vertebrate orthologue of C. elegans VAB-9, a tetraspan adherens junction protein in the PMP22/EMP/Claudin family of proteins. VAB-9 regulates cell morphology and adhesion in C. elegans and TMEM47 is expressed during kidney de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcd0b1c07e7eaa94ed186216cf703299
https://doi.org/10.1002/dvdy.24404
https://doi.org/10.1002/dvdy.24404
Autor:
Elisabeth Cox-Paulson, Shoichiro Ono, Thomas Gallagher, Nicole Vissichelli, Gary Mantione, Harold Hoops, Corey M. Hoffman, Rachel L. Walker, Vincent L. Cannataro, Malan Silva, Jeffrey S. Simske, Matthew Mcintosh
Publikováno v:
Developmental Dynamics. 243:753-764
Background: Tropomodulins are actin-capping proteins that regulate the stability of the slow-growing, minus-ends of actin filaments. The C. elegans tropomodulin homolog, UNC-94, has sequence and functional similarity to vertebrate tropomodulins. We i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3466caf26df8d32dece37c9041abfc24
https://doi.org/10.1002/dvdy.24118
https://doi.org/10.1002/dvdy.24118
Autor:
Mathias Köppen, Jeffrey S. Simske, Jeff Hardin, Jonathan Hodgkin, Alicia Yonkof, Paul A. Sims
Publikováno v:
Nature Cell Biology. 5:619-625
Epithelial cell junctions are essential for cell polarity, adhesion and morphogenesis. We have analysed VAB-9, a cell junction protein in Caenorhabditis elegans. VAB-9 is a predicted four-pass integral membrane protein that has greatest similarity to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20ce7272d74a1f542d58884a95d35962
https://doi.org/10.1038/ncb1002
https://doi.org/10.1038/ncb1002
Autor:
Anthony D. Radice, Paul A. Sims, David H. Hall, Christopher Rongo, Jeff Hardin, Bonnie L. Firestein, Jeffrey S. Simske, Mathias Köppen
Publikováno v:
Nature Cell Biology. 3:983-991
The function of epithelial cell sheets depends on the integrity of specialized cell-cell junctions that connect neighbouring cells. We have characterized the novel coiled-coil protein AJM-1, which localizes to an apical junctional domain of Caenorhab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ecf00e7deac71114027d447ba8b3ef5
https://doi.org/10.1038/ncb1101-983
https://doi.org/10.1038/ncb1101-983
Autor:
Jeff Hardin, Jeffrey S. Simske
Publikováno v:
BioEssays. 23:12-23
Summary The change in shape of the C. elegans embryo from an ovoid ball of cells into a worm-shaped larva is driven by three events within the cells of the hypodermis (epidermis): (1) intercalation of two rows of dorsal cells, (2) enclosure of the ve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2a935adcc37ccfbde5b2057e3c4ee5c
https://doi.org/10.1002/1521-1878(200101)23:1<12::aid-bies1003>3.0.co
https://doi.org/10.1002/1521-1878(200101)23:1<12::aid-bies1003>3.0.co
Publikováno v:
Current Biology. 8(19):1087-1091
Cell fusions produce multinucleate syncytia that are crucial to the structure of essential tissues in many organisms [1–5]. In humans the entire musculature, much of the placenta, and key cells in bones and blood are derived from cell fusion. Yet t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a37af2bd84f939d557a6586f91833485
Autor:
Dae-Gon Ha, Adityarup Chakravorty, Michael B. Miller, Rebecca E. K. Mandt, Jeffrey S. Simske, Leah Imlay, Charlotte R. Feddersen, Rachel Weinstein, Vida Praitis, Sarah Kniss, Walter Liszewski, Alexander Sullivan-Wilson, Juliet Mushi, Angela Schacht Farrell, Tyson Stock
Publikováno v:
PLoS Genetics, Vol 9, Iss 5, p e1003506 (2013)
PLoS Genetics
PLoS Genetics
Maintaining levels of calcium in the cytosol is important for many cellular events, including cell migration, where localized regions of high calcium are required to regulate cytoskeletal dynamics, contractility, and adhesion. Studies show inositol-t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c28f36545980435fdb6fb033facac6ca
http://europepmc.org/articles/PMC3656159?pdf=render
http://europepmc.org/articles/PMC3656159?pdf=render
Publikováno v:
American journal of physiology. Cell physiology. 301(6)
TM4SF10 [transmembrane tetra( 4 )-span family 10] is a claudin-like cell junction protein that is transiently expressed during podocyte development where its expression is downregulated in differentiating podocytes coincident with the appearance of n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64073cb8ec246e65a155c24096fb6b6d
https://pubmed.ncbi.nlm.nih.gov/21881001
https://pubmed.ncbi.nlm.nih.gov/21881001
Autor:
Jeffrey S, Simske, Jeff, Hardin
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 762
In the last decade, the claudin family of integral membrane proteins has been identified as the major protein component of the tight junctions in all vertebrates. The claudin superfamily proteins also function to regulate channel activity, intercellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a33dc20cb905277096ce4db9b967d469
https://pubmed.ncbi.nlm.nih.gov/21717355
https://pubmed.ncbi.nlm.nih.gov/21717355