Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Jeffrey S. Phillips"'
Autor:
Sanaz Arezoumandan, Katheryn A.Q. Cousins, Daniel T. Ohm, MaKayla Lowe, Min Chen, James Gee, Jeffrey S. Phillips, Corey T. McMillan, Kelvin C. Luk, Andres Deik, Meredith A. Spindler, Thomas F. Tropea, Daniel Weintraub, David A. Wolk, Murray Grossman, Virginia Lee, Alice S. Chen‐Plotkin, Edward B. Lee, David J. Irwin
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 3, Pp 673-685 (2024)
Abstract Objective Alzheimer's disease neuropathologic change and alpha‐synucleinopathy commonly co‐exist and contribute to the clinical heterogeneity of dementia. Here, we examined tau epitopes marking various stages of tangle maturation to test
Externí odkaz:
https://doaj.org/article/cdc2ad75ef8743d99fac2e3feb9bcc6b
Autor:
Ting Shen, Jacob W. Vogel, Jeffrey Duda, Jeffrey S. Phillips, Philip A. Cook, James Gee, Lauren Elman, Colin Quinn, Defne A. Amado, Michael Baer, Lauren Massimo, Murray Grossman, David J. Irwin, Corey T. McMillan
Publikováno v:
Translational Neurodegeneration, Vol 12, Iss 1, Pp 1-20 (2023)
Abstract Background TDP-43 proteinopathies represent a spectrum of neurological disorders, anchored clinically on either end by amyotrophic lateral sclerosis (ALS) and frontotemporal degeneration (FTD). The ALS–FTD spectrum exhibits a diverse range
Externí odkaz:
https://doaj.org/article/2b11c89bb7724f18adf67758d44d34c1
Autor:
Jeffrey S. Phillips, Nagesh Adluru, Moo K. Chung, Hamsanandini Radhakrishnan, Christopher A. Olm, Philip A. Cook, James C. Gee, Katheryn A. Q. Cousins, Sanaz Arezoumandan, David A. Wolk, Corey T. McMillan, Murray Grossman, David J. Irwin
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
IntroductionMultimodal evidence indicates Alzheimer’s disease (AD) is characterized by early white matter (WM) changes that precede overt cognitive impairment. WM changes have overwhelmingly been investigated in typical, amnestic mild cognitive imp
Externí odkaz:
https://doaj.org/article/982254d1016246fcba223287b0b73d9f
Autor:
Nicole R. Nissim, Denise Y. Harvey, Christopher Haslam, Leah Friedman, Pandurang Bharne, Geneva Litz, Jeffrey S. Phillips, Katheryn A. Q. Cousins, Sharon X. Xie, Murray Grossman, Roy H. Hamilton
Publikováno v:
Frontiers in Human Neuroscience, Vol 16 (2022)
ObjectivesWe hypothesized that measures of cortical thickness and volume in language areas would correlate with response to treatment with high-definition transcranial direct current stimulation (HD-tDCS) in persons with primary progressive aphasia (
Externí odkaz:
https://doaj.org/article/35f1f14d4d2540bf9e3ff417872ef2ee
Autor:
David G. Coughlin, H. Branch Coslett, Claire Peterson, Jeffrey S. Phillips, Corey McMillan, Edward B. Lee, John Q. Trojanowski, Murray Grossman, David J. Irwin
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 8, Iss 1, Pp n/a-n/a (2022)
Abstract Introduction Lewy body diseases are pathologically characterized by α‐synuclein pathology. Alzheimer's disease (AD) co‐pathology can influence phenotypes. In vivo AD biomarkers can suggest the presence of this co‐pathology in unusual
Externí odkaz:
https://doaj.org/article/08c1dc227b1d40899f01c3f14a58ef8b
Autor:
Nikolas G. Kinney, Jessica Bove, Jeffrey S. Phillips, Katheryn A.Q Cousins, Christopher A. Olm, Daniel G. Wakeman, Corey T. McMillan, Lauren Massimo
Publikováno v:
NeuroImage: Clinical, Vol 30, Iss , Pp 102629- (2021)
Behavioral variant frontotemporal degeneration (bvFTD) is clinically characterized by progressive decline in social and executive domains. Previous work suggests that early lifestyle factors such as education and occupational attainment may relate to
Externí odkaz:
https://doaj.org/article/0d1fa5a212084aa0b96e98f656229ee6
Autor:
Boram Kim, EunRan Suh, Aivi T. Nguyen, Stefan Prokop, Bailey Mikytuck, Olamide A. Olatunji, John L. Robinson, Murray Grossman, Jeffrey S. Phillips, David J. Irwin, Dawn Mechanic-Hamilton, David A. Wolk, John Q. Trojanowski, Corey T. McMillan, Vivianna M. Van Deerlin, Edward B. Lee
Publikováno v:
Acta Neuropathologica. 144:1085-1102
Alzheimer's disease (AD) has multiple clinically and pathologically defined subtypes where the underlying causes of such heterogeneity are not well established. Rare TREM2 variants confer significantly increased risk for clinical AD in addition to ot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63a657e4d004bc3498a04a5309d3b0e0
https://doi.org/10.1007/s00401-022-02495-4
https://doi.org/10.1007/s00401-022-02495-4
Autor:
Min Chen, Daniel T. Ohm, Jeffrey S. Phillips, Corey T. McMillan, Noah Capp, Claire Peterson, Emily Xie, David A. Wolk, John Q. Trojanowski, Edward B. Lee, James Gee, Murray Grossman, David J. Irwin
Publikováno v:
The Journal of Neuroscience. 42:3868-3877
Network analyses inform complex systems such as human brain connectivity, but this approach is seldom applied to gold-standard histopathology. Here, we use two complimentary computational approaches to model microscopic progression of the main subtyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bff9ce880d758738aeb88848c810432
https://doi.org/10.1523/jneurosci.2061-21.2022
https://doi.org/10.1523/jneurosci.2061-21.2022
Autor:
Saurabh Sihag, Lauren Massimo, Sarah E Burke, Jeffrey S Phillips, Philip Cook, Jeffrey T Duda, James C. Gee, Theodore Satterthwaite, Murray Grossman, Michael Benatar, Corey T McMillan
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53bd496d00e8c2c3aed37d38e67e4cc6
https://doi.org/10.1002/alz.066119
https://doi.org/10.1002/alz.066119
Autor:
Emma Rhodes, Lauren Massimo, Dawn Mechanic‐Hamilton, Corey T McMillan, Jeffrey S Phillips, Sarah E Burke, Quinn Hlava, Philip Cook, James C. Gee, Murray Grossman
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e660c86d590af94c5612d401b59beb2
https://doi.org/10.1002/alz.067714
https://doi.org/10.1002/alz.067714