Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Jeffrey S. Painter"'
Autor:
Christopher A. Miller, Jason R. Walker, Travis L. Jensen, William F. Hooper, Robert S. Fulton, Jeffrey S. Painter, Mikkael A. Sekeres, Timothy J. Ley, David H. Spencer, Johannes B. Goll, Matthew J. Walter
Publikováno v:
The Journal of Molecular Diagnostics. 24:219-223
The U2AF1 gene is a core part of mRNA splicing machinery and frequently contains somatic mutations that contribute to oncogenesis in myelodysplastic syndrome, acute myeloid leukemia, and other cancers. A change introduced in the GRCh38 version of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a88e1ba5142541bb36fd794d4030dee
https://doi.org/10.1016/j.jmoldx.2021.10.013
https://doi.org/10.1016/j.jmoldx.2021.10.013
Autor:
Rafael Bejar, Dana E. Rollison, Ling Zhang, Rami S. Komrokji, Chaomei Zhang, Markus Ball, Pearlie K. Epling-Burnette, Matthew J. Walter, Jeffrey S. Painter, Lynn C. Moscinski, Mikkael A. Sekeres, Eric Padron, Sean J. Yoder, Steven D. Gore, Jamie K. Teer
Publikováno v:
Blood. 131(21)
TO THE EDITOR: Population-level germ line heterogeneity, rare single nucleotide polymorphisms (SNPs), and sequence alignment to a single reference genome make it challenging for variant-calling algorithms to distinguish germ line variants from somati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69b4e81a042acc08cd220eca2027ef36
https://pubmed.ncbi.nlm.nih.gov/29661788
https://pubmed.ncbi.nlm.nih.gov/29661788
Autor:
Eric Solary, Pearlie K. Epling-Burnette, Rami S. Komrokji, Nana Ben-Crentsil, Thomas Cluzeau, Jeffrey S. Painter, A. Robert MacLeod, Ariel Quintana, Hailing Zhang, Abhishek Dhawan, Maria E. Balasis, Hannah Newman, Alexis Vedder, Traci Kruer, Christopher Letson, Nathalie Droin, Jane Merlevede, Alan F. List, Eric Padron, Kathy L. McGraw, Sheng Wei, Lei Sun
Publikováno v:
Blood. 134:1692-1692
Improvements in antisense technology have now enabled clinically relevant therapeutic credentialing of the noncoding genome. MALAT1 is a long non-coding RNA that, among other functions, is thought to serve as a nuclear scaffold for splicing and trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be47ada43dc35c23bb4544d7c32e89c6
https://doi.org/10.1182/blood-2019-128573
https://doi.org/10.1182/blood-2019-128573
Autor:
Rami S. Komrokji, Sheng Wei, Xiubao Ren, Jaroslaw P. Maciejewski, Pearlie K. Epling-Burnette, Jeffrey S. Painter, Rangasudhagar Radhakrishnan, Dana E. Rollison, Thomas P. Loughran, Alan F. List, Adam W. Mailloux, Ronald Paquette, Lili Yang, Kathy L. McGraw, Hideki Makishima
Publikováno v:
Leukemia
Telomeres are specialized structures providing chromosome integrity during cellular division along with protection against premature senescence and apoptosis. Accelerated telomere attrition in patients with myelodysplastic syndrome (MDS) occurs by an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a22bdebbb4e741d1bf5d1e0e15eab9b8
https://doi.org/10.1038/leu.2012.300
https://doi.org/10.1038/leu.2012.300
Autor:
Jörg J. Goronzy, Elaine M. Sloand, Jeffrey S. Painter, Dana E. Rollison, Denise Cosgrove, P.K. Epling-Burnette, David Boulware, JianXiang Zou, Dung-Tsa Chen, Sheng Wei, Alan F. List, Fanqi Bai, Loretta Pfannes
Publikováno v:
Leukemia. 23:1288-1296
Response to immunosuppressive therapy (IST) in younger patients with myelodysplastic syndrome (MDS) has been linked to a T-cell-dominant autoimmune process that impairs hematopoiesis. Analysis of the age-adjusted CD4:CD8 ratio in 76 MDS patients comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9d8bd8e0d97c8a512917e7f307ed170
https://doi.org/10.1038/leu.2009.14
https://doi.org/10.1038/leu.2009.14
Autor:
Sheng Wei, Junmin Zhou, Jeffrey A. Yoder, Pearlie K. Epling-Burnette, Jeffrey S. Painter, Julie Y. Djeu, Lynn C. Moscinski, Michelle A. Blaskovich, Said M. Sebti, X. Chen, JianXiang Zou, Fanqi Bai, Lubomir Sokol, Todd D. Edwards, Thomas P. Loughran
Publikováno v:
Blood. 112:4694-4698
Large granular lymphocyte (LGL) leukemia is commonly associated with poor hematopoiesis. The first case of pulmonary artery hypertension (PAH) was observed in a 57-year-old woman with natural killer (NK)–LGL leukemia and transfusion-dependent anemi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ec3754bd0a92c758698f193db23e904
https://doi.org/10.1182/blood-2008-02-136382
https://doi.org/10.1182/blood-2008-02-136382
Autor:
Matthias Krusch, Bin Zhong, Helmut R. Salih, Jeffrey S. Painter, Sheng Wei, Pearlie K. Epling-Burnette, Edna Ku, David Boulware, Lynn C. Moscinski, Julie Y. Djeu, JianXiang Zou, Dana E. Rollison, Alan F. List, Fanqi Bai
Publikováno v:
Blood. 109:4816-4824
Myelodysplastic syndromes (MDS) are characterized by ineffective hematopoiesis with potential for progression to acute myeloid leukemia (AML). We compared natural killer (NK) cytolytic function in 48 MDS patients with 37 healthy donors and found redu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdb489d98e98114d9a49d89e3d39111a
https://doi.org/10.1182/blood-2006-07-035519
https://doi.org/10.1182/blood-2006-07-035519
Autor:
D Vendron, Jeffrey S. Painter, Dana E. Rollison, Pearlie K. Epling-Burnette, R Widen, David Boulware, Alan F. List, Fanqi Bai, E. Ku, JianXiang Zou
Publikováno v:
Leukemia. 21:659-667
Selected patients with Myelodysplastic Syndromes (MDS) are responsive to immunosuppressive therapy, suggesting that hematopoietic suppressive T cells have a pathogenic role in ineffective hematopoiesis. We assessed T-cell receptor (TCR) clonality thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::156bc261f01558cef9145d88827b7871
https://doi.org/10.1038/sj.leu.2404590
https://doi.org/10.1038/sj.leu.2404590
Autor:
Rami S. Komrokji, Eduardo M. Sotomayor, Pearlie K. Epling-Burnette, Alan F. List, Ling Zhang, Sean Yoder, Jaroslaw P. Maciejewski, Jeffrey E. Lancet, Eric Padron, Jamie K. Teer, Jeffrey S. Painter, Najla Al Ali, Mikkael A. Sekeres, Tania Mesa, Sateesh S Kunigal
Publikováno v:
Blood. 123(23)
To the editor: The genetic determinants that govern the phenotype associated with chronic myelomonocytic leukemia (CMML) and myelodysplastic syndromes (MDS) are unknown. Many recurrent mutations occur in both diseases, suggesting that the presence or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e894902305d132a603551d2feaee7cd
https://pubmed.ncbi.nlm.nih.gov/24904105
https://pubmed.ncbi.nlm.nih.gov/24904105
Autor:
Jeffrey S. Painter, Ibrahim Buyuksal, William S. Dalton, Rachel Burke, Terry H. Landowski, Lynn C. Moscinski, Steven C. Goldstein
Publikováno v:
Leukemia & Lymphoma. 42:835-846
The CD95 receptor, also known as Fas/Apo-1, is a member of the Tumor Necrosis Factor receptor (TNF-R) family of death receptors. Apoptosis mediated by CD95 plays a central role in maintaining homeostasis of the immune system. Dysregulation of the CD9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e32cfd0a4dd50ae8a85409488eed90a
https://doi.org/10.3109/10428190109097702
https://doi.org/10.3109/10428190109097702