Výsledky vyhledávání - "Jeffrey S. Monette"

Patients With Coronary Endothelial Dysfunction Have Impaired Cholesterol Efflux Capacity and Reduced HDL Particle Concentration

Autor: Amir Lerman, Angela Irwin, Chongren Tang, Jeffrey S. Monette, Baohai Shao, Jaskanwal D. Sara, Graziella E. Ronsein, Jay W. Heinecke, Patrick M. Hutchins, Jake Wimberger, Tomas Vaisar

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Rationale: Coronary endothelial dysfunction (ED)—an early marker of atherosclerosis—increases the risk of cardiovascular events. Objective: We tested the hypothesis that cholesterol efflux capacity and high-density lipoprotein (HDL) particle conc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2be88135982aa6004ee4477d9d706f3
https://doi.org/10.1161/circresaha.116.308357

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(R)-α-Lipoic acid treatment restores ceramide balance in aging rat cardiac mitochondria

Autor: Liam A. Finlay, Régis F. Moreau, Jeffrey S. Monette, Kate Petersen Shay, Tory M. Hagen, Luis A. Gómez, Eric J. Smith, J. A. Butler, Alexander J. Michels, Kevin C. Dunn

Publikováno v: Pharmacological Research. 63:23-29

Inflammation results in heightened mitochondrial ceramide levels, which cause electron transport chain dysfunction, elevates reactive oxygen species, and increases apoptosis. As mitochondria in aged hearts also display many of these characteristics,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdce62a7b018068224d322d2824875c6
https://doi.org/10.1016/j.phrs.2010.09.007

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Selective fluorescent imaging of superoxide in vivo using ethidium-based probes

Autor: Jeffrey S. Monette, Tory M. Hagen, Joseph S. Beckman, Meredith F. Ross, Mariana Pehar, Michael P. Murphy, Kristine M. Robinson, Michael S. Janes

Publikováno v: Proceedings of the National Academy of Sciences. 103:15038-15043

The putative oxidation of hydroethidine (HE) has become a widely used fluorescent assay for the detection of superoxide in cultured cells. By covalently joining HE to a hexyl triphenylphosphonium cation (Mito-HE), the HE moiety can be targeted to mit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9abd58b311be9ad717aba47bc930a0af
https://doi.org/10.1073/pnas.0601945103

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Quantification of HDL particle concentration by calibrated ion mobility analysis

Autor: Patrick M. Hutchins, Jay W. Heinecke, Gail P. Jarvik, Tomas Vaisar, Jane E. Ranchalis, Yi He, Gattadahalli M. Anantharamaiah, Jeffrey S. Monette, Jake Wimberger, Nathalie Pamir, Graziella E. Ronsein, Daniel Seung Kim

Publikováno v: Clinical chemistry. 60(11)

BACKGROUNDIt is critical to develop new metrics to determine whether HDL is cardioprotective in humans. One promising approach is HDL particle concentration (HDL-P), the size and concentration of HDL in plasma. However, the 2 methods currently used t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59fd955b416106a0ae3f97e54ecb87a1
https://pubmed.ncbi.nlm.nih.gov/25281702

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R-α-lipoic acid does not reverse hepatic inflammation of aging, but lowers lipid anabolism, while accentuating circadian rhythm transcript profiles

Autor: Jeffrey S. Monette, Alex J. Michels, Tory M. Hagen, Régis F. Moreau, Liam A. Finlay, Judy Ann Butler, Shay Kate Petersen, Balz Frei, Eric J. Smith

Publikováno v: American journal of physiology. Regulatory, integrative and comparative physiology. 302(5)

To determine the effects of age and lipoic acid supplementation on hepatic gene expression, we fed young (3 mo) and old (24 mo) male Fischer 344 rats a diet with or without 0.2% (wt/wt) R-α-lipoic acid (LA) for 2 wk. Total RNA isolated from liver ti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d74b760bda9c10669cc52270999b5bf
https://pubmed.ncbi.nlm.nih.gov/22049228

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Characteristics of the Rat Cardiac Sphingolipid Pool in Two Mitochondrial Subpopulations

Autor: Brett A. Bemer, Tory M. Hagen, Luis A. Gómez, Jeffrey S. Monette, Alan W. Taylor, Régis F. Moreau

Mitochondrial sphingolipids play a diverse role in normal cardiac function and diseases, yet a precise quantification of cardiac mitochondrial sphingolipids has never been performed. Therefore, rat heart interfibrillary mitochondria (IFM) and subsarc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26a206506a36a90a6a178b3df9c30a37
https://europepmc.org/articles/PMC2939858/

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Corrigendum to 'Characteristics of the rat cardiac sphingolipid pool in two mitochondrial subpopulations' [Biochem. Biophys. Res. Commun. 398 (2010) 272–277]

Autor: Alan W. Taylor, Tory M. Hagen, Jeffrey S. Monette, Brett A. Bemer, Régis Moreau, Luis A. Gómez

Publikováno v: Biochemical and Biophysical Research Communications. 404:1111

The author regrets an error in the legend for Fig. 3. The legend appears correctly below: Fig. 3. Ceramide isotypes in mitochondrial and extra-mitochondrial cardiac membranes. Ceramides were quantified in indicated cardiac membranes using LC/MS/MS. R

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fb43b58262cb0d54e2cd742e9e0e7497
https://doi.org/10.1016/j.bbrc.2010.11.073

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