Zobrazeno 1 - 10
of 251
pro vyhledávání: '"Jeffrey S. Dome"'
Autor:
Andrew J. Murphy, Changde Cheng, Justin Williams, Timothy I. Shaw, Emilia M. Pinto, Karissa Dieseldorff-Jones, Jack Brzezinski, Lindsay A. Renfro, Brett Tornwall, Vicki Huff, Andrew L. Hong, Elizabeth A. Mullen, Brian Crompton, Jeffrey S. Dome, Conrad V. Fernandez, James I. Geller, Peter F. Ehrlich, Heather Mulder, Ninad Oak, Jamie Maciezsek, Carolyn M. Jablonowski, Andrew M. Fleming, Prahalathan Pichavaram, Christopher L. Morton, John Easton, Kim E. Nichols, Michael R. Clay, Teresa Santiago, Jinghui Zhang, Jun Yang, Gerard P. Zambetti, Zhaoming Wang, Andrew M. Davidoff, Xiang Chen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Developing synchronous bilateral Wilms tumor suggests an underlying (epi)genetic predisposition. Here, we evaluate this predisposition in 68 patients using whole exome or genome sequencing (n = 85 tumors from 61 patients with matched germlin
Externí odkaz:
https://doaj.org/article/946f460fad5e41959f9465bb4f236137
Autor:
Andrew J. Murphy, Xiang Chen, Emilia M. Pinto, Justin S. Williams, Michael R. Clay, Stanley B. Pounds, Xueyuan Cao, Lei Shi, Tong Lin, Geoffrey Neale, Christopher L. Morton, Mary A. Woolard, Heather L. Mulder, Hyea Jin Gil, Jerold E. Rehg, Catherine A. Billups, Matthew L. Harlow, Jeffrey S. Dome, Peter J. Houghton, John Easton, Jinghui Zhang, Rani E. George, Gerard P. Zambetti, Andrew M. Davidoff
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
The progress in pre-clinical drug discovery for Wilms tumor (WT) is limited by a lack of disease models. Here, the authors develop 45 heterotopic WT patient-derived xenografts including several anaplastic models that recapitulate the biological heter
Externí odkaz:
https://doaj.org/article/db96314ad7db4fb39fc7295bd2b1e60c
Autor:
Samantha Gadd, Vicki Huff, Chiang-Ching Huang, E. Cristy Ruteshouser, Jeffrey S. Dome, Paul E. Grundy, Norman Breslow, Lawrence Jennings, Daniel M. Green, J. Bruce Beckwith, Elizabeth J. Perlman
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 8, Pp 742-756 (2012)
Wilms tumors (WT) have provided broad insights into the interface between development and tumorigenesis. Further understanding is confounded by their genetic, histologic, and clinical heterogeneity, the basis of which remains largely unknown. We eval
Externí odkaz:
https://doaj.org/article/645ccf46a1b8404b9235379f5a0e3b1f
Publikováno v:
Journal of Clinical Oncology. 40:1853-1860
The Oncology Grand Rounds series is designed to place original reports published in the Journal into clinical context. A case presentation is followed by a description of diagnostic and management challenges, a review of the relevant literature, and
Autor:
Michael V. Ortiz, Christa Koenig, Amy E. Armstrong, Jesper Brok, Beatriz de Camargo, Annelies M. C. Mavinkurve‐Groothuis, Thelma B. Velasquez Herrera, Rajkumar Venkatramani, Andrew D. Woods, Jeffrey S. Dome, Filippo Spreafico
Publikováno v:
Pediatric Blood & Cancer. 70
Autor:
Elizabeth J. Perlman, Julie M. Gastier-Foster, Nicole Ross, Ronald R. de Krijger, Marry M. van den Heuvel-Eibrink, Amy L. Walz, Oliver A. Hampton, David A. Wheeler, Jing Ma, Charles G. Mullighan, James I. Geller, Jing Tian, Yueh-Yun Chi, Jeffrey S. Dome, Vicki Huff, Marco A. Marra, Richard A. Moore, Andrew J. Mungall, Zusheng Zong, Yussanne Ma, Ying Hu, Cu Nguyen, Chunhua Yan, Chih Hao Hsu, Qing-Rong Chen, Daoud Meerzaman, Jaime M. Guidry Auvil, Malcolm A. Smith, Daniela S. Gerhard, Samantha Gadd, Ariadne H.A.G. Ooms
Purpose: To investigate the role and significance of TP53 mutation in diffusely anaplastic Wilms tumors (DAWTs).Experimental Design: All DAWTs registered on National Wilms Tumor Study-5 (n = 118) with available samples were analyzed for TP53 mutation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41e5ffc41c18b2d4c2506525d3dba9a1
https://doi.org/10.1158/1078-0432.c.6524982
https://doi.org/10.1158/1078-0432.c.6524982