Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jeffrey S. Burgdorf"'
Publikováno v:
Frontiers in Psychology, Vol 15 (2024)
This paper advocates for considering disgust as a primary emotional system within Panksepp’s Affective Neuroscience framework, which has the potential to improve the efficacy of psychotherapy with obsessive-compulsive disorder, hypochondriasis, and
Externí odkaz:
https://doaj.org/article/7c5500bb53474dcf9f3c54a420a2ceb9
Autor:
Jeffrey S. Burgdorf, Joseph R. Moskal
Publikováno v:
Discover Mental Health, Vol 3, Iss 1, Pp 1-10 (2023)
Abstract Positive and negative emotional states in rats can be studied by investigating ultrasonic vocalizations (USVs). Positive affect in rats is indexed by 50 kHz hedonic USVs, and negative affect is indexed by 22 kHz aversive calls. We examined t
Externí odkaz:
https://doaj.org/article/dd720bdf04e54eef91de83b3a00aed3c
Publikováno v:
Brain Sciences, Vol 11, Iss 11, p 1390 (2021)
Since the realization that human emotional experiences and behavior evolved from mammalian ancestors and are evolutionary continuations of animal emotional behavior [...]
Externí odkaz:
https://doaj.org/article/039fa32b87ec4776a576da7eddb46700
Autor:
Jeffrey S. Burgdorf, Sehyoun Yoon, Marc Dos Santos, Catherine R. Lammert, Joseph R. Moskal, Peter Penzes
Publikováno v:
Mol Psychiatry
We developed an IGFBP2-mimetic peptide fragment, JB2, and showed that it promotes basal synaptic structural and functional plasticity in cultured neurons and mice. We demonstrate that JB2 directly binds to dendrites and synapses, and its biological a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bae0bf2b348342eacd12fd046595582
https://doi.org/10.1038/s41380-022-01904-0
https://doi.org/10.1038/s41380-022-01904-0
Autor:
Xiao-lei Zhang, Nils A. Berglund, Jeffrey S. Burgdorf, John E. Donello, Joseph R. Moskal, Patric K. Stanton
Publikováno v:
Zhang, X L, Berglund, N A, Burgdorf, J S, Donello, J E, Moskal, J R & Stanton, P K 2022, ' Extracellular application of the N-methyl-D-aspartate receptor allosteric modulator rapastinel acts remotely to regulate Ca 2+ inactivation at an intracellular locus ', NeuroReport, vol. 33, no. 7, pp. 312-319 . https://doi.org/10.1097/WNR.0000000000001787
Background A novel N-methyl-D-aspartate receptor (NMDAR) allosteric modulator, rapastinel (RAP, formerly GLYX-13), elicits long-lasting antidepressant-like effects by enhancing long-term potentiation (LTP) of synaptic transmission. RAP elicits these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::857d7e1097f3ea8cd8e86e4ca126be02
https://pubmed.ncbi.nlm.nih.gov/35594441
https://pubmed.ncbi.nlm.nih.gov/35594441
Autor:
M Dolores, Martín-de-Saavedra, Marc, Dos Santos, Lorenza, Culotta, Olga, Varea, Benjamin P, Spielman, Euan, Parnell, Marc P, Forrest, Ruoqi, Gao, Sehyoun, Yoon, Emmarose, McCoig, Hiba A, Jalloul, Kristoffer, Myczek, Natalia, Khalatyan, Elizabeth A, Hall, Liam S, Turk, Antonio, Sanz-Clemente, Davide, Comoletti, Stefan F, Lichtenthaler, Jeffrey S, Burgdorf, Maria V, Barbolina, Jeffrey N, Savas, Peter, Penzes
Publikováno v:
Neuron
While many neuronal, membrane proteins undergo proteolytic cleavage, little is known about the biological significance of neuronal ectodomain shedding (ES). Here, we show that the neuronal sheddome is detectable in human cerebrospinal fluid (hCSF) an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::985e4b81ac4a25d2d5b2fbee13d702c6
https://pubmed.ncbi.nlm.nih.gov/34921780
https://pubmed.ncbi.nlm.nih.gov/34921780
Publikováno v:
The international journal of neuropsychopharmacology. 25(12)
Background The role of glutamatergic receptors in major depressive disorder continues to be of great interest for therapeutic development. Recent studies suggest that both negative and positive modulation of N-methyl-D-aspartate receptors (NMDAR) can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fe5e42d57e3ff131c2b1a7113ba8e82
https://pubmed.ncbi.nlm.nih.gov/35882204
https://pubmed.ncbi.nlm.nih.gov/35882204
Autor:
M. Dolores Martín-de-Saavedra, Marc Dos Santos, Lorenza Culotta, Olga Varea, Benjamin P. Spielman, Euan Parnell, Marc P. Forrest, Ruoqi Gao, Sehyoun Yoon, Emmarose McCoig, Hiba A. Jalloul, Kristoffer Myczek, Natalia Khalatyan, Elizabeth A. Hall, Liam S. Turk, Antonio Sanz-Clemente, Davide Comoletti, Stefan F. Lichtenthaler, Jeffrey S. Burgdorf, Maria V. Barbolina, Jeffrey N. Savas, Peter Penzes
Publikováno v:
Neuron 110(4), 627-643.e9 (2022). doi:10.1016/j.neuron.2021.11.025
Although many neuronal membrane proteins undergo proteolytic cleavage, little is known about the biological significance of neuronal ectodomain shedding (ES). Here, we show that the neuronal sheddome is detectable in human cerebrospinal fluid (hCSF)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1537b9626520b0a547915072c4dcf251
https://doi.org/10.1016/j.neuron.2021.11.025
https://doi.org/10.1016/j.neuron.2021.11.025
Autor:
Nayereh, Ghoreishi-Haack, Jessica M, Priebe, Jacqueline D, Aguado, Elizabeth M, Colechio, Jeffrey S, Burgdorf, M Scott, Bowers, Cassia N, Cearley, M Amin, Khan, Joseph R, Moskal
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 366(3)
NYX-2925 [(2S,3R)-3-hydroxy-2-((R)-5-isobutyryl-1-oxo-2,5-diazaspiro[3.4]octan-2-yl)butanamide] is a novel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fc5551bfac0f644284c215a8ad570990
https://pubmed.ncbi.nlm.nih.gov/29986951
https://pubmed.ncbi.nlm.nih.gov/29986951