Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Jeffrey S Harding"'
Autor:
Heidi A Schreiber, Paul D Hulseberg, JangEun Lee, Jozsef Prechl, Peter Barta, Nora Szlavik, Jeffrey S Harding, Zsuzsanna Fabry, Matyas Sandor
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11453 (2010)
Mycobacterium-induced granulomas are the interface between bacteria and host immune response. During acute infection dendritic cells (DCs) are critical for mycobacterial dissemination and activation of protective T cells. However, their role during c
Externí odkaz:
https://doaj.org/article/ac4b3b5004d8408999baec4308321900
Autor:
Martin Hsu, Aditya Rayasam, Julie A. Kijak, Yun Hwa Choi, Jeffrey S. Harding, Sarah A. Marcus, William J. Karpus, Matyas Sandor, Zsuzsanna Fabry
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Lymphangiogenesis occurs in the context of systemic inflammation and development but has not been reported for the lymphatics that surround the CNS. Here the authors show that in the context of experimental autoimmune encephatlitis, lymphangiogenesis
Externí odkaz:
https://doaj.org/article/adb4bdd81e9e458aa8bdad35a32985c3
Autor:
Melinda Herbáth, Anna Ritter, Zsuzsanna Fabry, Jeffrey S. Harding, Matyas Sandor, George Hasko, Yuli Chen, Andras Nagy, Balázs Csóka, Aditya Rayasam, Iacovos P. Michael
Publikováno v:
Cell Reports, Vol 27, Iss 7, Pp 2119-2131.e6 (2019)
Summary: Many autoimmune and infectious diseases are characterized by the formation of granulomas which are inflammatory lesions that consist of spatially organized immune cells. These sites protect the host and control pathogens like Mycobacterium t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a44a23755efcee00fc086c20d0268caa
http://www.sciencedirect.com/science/article/pii/S2211124719305455
http://www.sciencedirect.com/science/article/pii/S2211124719305455
Autor:
Julie A. Kijak, Zsuzsanna Fabry, Matyas Sandor, William J. Karpus, Aditya Rayasam, Sarah A. Marcus, Jeffrey S. Harding, Yun Hwa Choi, Martin Hsu
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
There are no conventional lymphatic vessels within the CNS parenchyma, although it has been hypothesized that lymphatics near the cribriform plate or dura maintain fluid homeostasis and immune surveillance during steady-state conditions. However, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aefa715708e68c9ce11fd9c57bb15d99
https://doaj.org/article/adb4bdd81e9e458aa8bdad35a32985c3
https://doaj.org/article/adb4bdd81e9e458aa8bdad35a32985c3
Autor:
Natalie Lisa Payne, Jeffrey S. Harding, Anne L. Fletcher, Andras Nagy, Alfie T. Baker, Konstantin Knoblich, Mohammed H. Abuwarwar
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 4
International Journal of Molecular Sciences, Vol 22, Iss 1827, p 1827 (2021)
Volume 22
Issue 4
International Journal of Molecular Sciences, Vol 22, Iss 1827, p 1827 (2021)
T cell immunotherapy is now a mainstay therapy for several blood-borne cancers as well as metastatic melanoma. Unfortunately, many epithelial tumors respond poorly to immunotherapy, and the reasons for this are not well understood. Cancer-associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1246d16afff76cf5a53559ac24ecd0a
Autor:
Aditya Rayasam, Leah Steinmetz, Martin Hsu, Jeffrey S. Harding, Julie A. Kijak, Anders Lindstedt, Melissa G. Harris, Matyas Sandor, Jozsef Karman, Zsuzsanna Fabry, McKenna Dallmann, Nicole Zindl
Publikováno v:
The Journal of Neuroscience. 38:7058-7071
T cells continuously sample CNS-derived antigens in the periphery, yet it is unknown how they sample and respond to CNS antigens derived from distinct brain areas. We expressed ovalbumin (OVA) neoepitopes in regionally distinct CNS areas (Cnp-OVA and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3670c4f58cbb06bf96049b22517ed3b6
https://doi.org/10.1523/jneurosci.0366-18.2018
https://doi.org/10.1523/jneurosci.0366-18.2018
Publikováno v:
Cell Stem Cell. 27:198-199
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7d26b76f078a2808997be155f8e8356
https://doi.org/10.1016/j.stem.2020.07.004
https://doi.org/10.1016/j.stem.2020.07.004
Autor:
Puzheng Zhang, Jeffrey S. Harding, Zohreh Izadifar, Mohammad Izadifar, Kristina Vintersten-Nagy, Andras Nagy, Jean Tang, Chengjin Li, Huijuan Yang, Maria V. Shutova, Mohammad Massumi
A vast number of diseases could be treated with therapeutic cells derived from pluripotent stem cells (PSCs). However, cell products that come from non-autologous sources can be immune rejected by the recipient’s immune system. Here, we show that f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a034e9a42fed81251fa7067f87ae351
https://doi.org/10.1101/716571
https://doi.org/10.1101/716571
Publikováno v:
The Journal of Immunology. 206:99.27-99.27
Granulomas provide protection against Mycobacterium tuberculosis (Mtb) infection and dissemination but also contribute to long term pathogen survival in the host. Macrophages are the dominant cell type in mycobacterial granulomas, playing a central r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cf212634fac6a997cb3b8a9fd70a45c
https://doi.org/10.4049/jimmunol.206.supp.99.27
https://doi.org/10.4049/jimmunol.206.supp.99.27
Autor:
Natalie Lisa Payne, J. Tang, Jeffrey S. Harding, X. Ma, Kristina Vintersten Nagy, Claudio Monetti, Qin Liang, Andras Nagy
Publikováno v:
Cytotherapy. 21:S13
Background & Aim Cell therapy-based regenerative medicine provides a powerful tool against diseases that have been intractable to treat with conventional medicine. Employing genome-editing strategies, we addressed the safety concerns associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d2b43acf6b57ec63db8219a1a110cd0
https://doi.org/10.1016/j.jcyt.2019.03.575
https://doi.org/10.1016/j.jcyt.2019.03.575