Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Jeffrey S Bourgeois"'
Autor:
Jeffrey S Bourgeois, Liuyang Wang, Agustin F Rabino, Jeffrey Everitt, Monica I Alvarez, Sahezeel Awadia, Erika S Wittchen, Rafael Garcia-Mata, Dennis C Ko
Publikováno v:
PLoS Pathogens, Vol 17, Iss 7, p e1009713 (2021)
Salmonella hijack host machinery in order to invade cells and establish infection. While considerable work has described the role of host proteins in invasion, much less is known regarding how natural variation in these invasion-associated host prote
Externí odkaz:
https://doaj.org/article/36b61b4de3bb4c32b3e73fb60442aa1a
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163182 (2016)
Cellular exposure to cigarette smoke leads to an array of complex responses including apoptosis, cellular senescence, telomere dysfunction, cellular aging, and neoplastic transformation. To study the cellular response to cigarette smoke, a common in
Externí odkaz:
https://doaj.org/article/d1c5123925744ad4b60fc63afbe8dbbd
Autor:
Jeffrey S. Bourgeois, Caroline E. Anderson, Liuyang Wang, Jennifer L. Modliszewski, Wei Chen, Benjamin H. Schott, Nicolas Devos, Dennis C. Ko
Publikováno v:
mBio, Vol 13, Iss 3 (2022)
ABSTRACT Despite being in a golden age of bacterial epigenomics, little work has systematically examined the plasticity and functional impacts of the bacterial DNA methylome. Here, we leveraged single-molecule, real-time sequencing (SMRT-seq) to exam
Externí odkaz:
https://doaj.org/article/3090fc8d729b4249b16805cdabb74d4f
Publikováno v:
Microbiology. 169
Borrelia burgdorferi is a pathogenic bacterium and the causative agent of Lyme disease. It is exposed to reactive oxygen species (ROS) in both the vertebrate and tick hosts. While some mechanisms by which B. burgdorferi ameliorates the effects of ROS
Autor:
Benjamin H, Schott, Liuyang, Wang, Xinyu, Zhu, Alfred T, Harding, Emily R, Ko, Jeffrey S, Bourgeois, Erica J, Washington, Thomas W, Burke, Jack, Anderson, Emma, Bergstrom, Zoe, Gardener, Suzanna, Paterson, Richard G, Brennan, Christopher, Chiu, Micah T, McClain, Christopher W, Woods, Simon G, Gregory, Nicholas S, Heaton, Dennis C, Ko
Publikováno v:
Cell genomics. 2(11)
During pandemics, individuals exhibit differences in risk and clinical outcomes. Here, we developed single-cell high-throughput human
Autor:
Benjamin H. Schott, Liuyang Wang, Xinyu Zhu, Alfred T. Harding, Emily R. Ko, Jeffrey S. Bourgeois, Erica J. Washington, Thomas W. Burke, Jack Anderson, Emma Bergstrom, Zoe Gardener, Suzanna Paterson, Richard G. Brennan, Christopher Chiu, Micah T. McClain, Christopher W. Woods, Simon G. Gregory, Nicholas S. Heaton, Dennis C. Ko
During pandemics, individuals exhibit differences in risk and clinical outcomes. Here, we developed single-cell high-throughput human in vitro susceptibility testing (scHi-HOST), a method for rapidly identifying genetic variants that confer resistanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9ba3d18cfb5edf87a1e40e2fbe068b3
http://hdl.handle.net/10044/1/100790
http://hdl.handle.net/10044/1/100790
Borrelia burgdorferi is a pathogenic bacterium and the causative agent of Lyme Disease. It is exposed to reactive oxygen species (ROS) in both the vertebrate and tick hosts. While some mechanisms by which B. burgdorferi ameliorates the effects of ROS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf86b32ca99d386817ea2d4ca0135314
https://doi.org/10.1101/2022.08.24.505212
https://doi.org/10.1101/2022.08.24.505212
Autor:
Kyle D. Gibbs, Liuyang Wang, Zhuo Yang, Caroline E. Anderson, Jeffrey S. Bourgeois, Yanlu Cao, Margaret R. Gaggioli, Martin Biel, Rosa Puertollano, Cheng-Chang Chen, Dennis C. Ko
Publikováno v:
Cell Genomics. 3:100290
Publikováno v:
Trends Microbiol
Humanity's ongoing struggle with new, re-emerging and endemic infectious diseases serves as a frequent reminder of the need to understand host-pathogen interactions. Recent advances in genomics have dramatically advanced our understanding of how gene
Autor:
Jeffrey S, Bourgeois, Caroline E, Anderson, Liuyang, Wang, Jennifer L, Modliszewski, Wei, Chen, Benjamin H, Schott, Nicolas, Devos, Dennis C, Ko
Publikováno v:
mBio. 13(3)
Despite being in a golden age of bacterial epigenomics, little work has systematically examined the plasticity and functional impacts of the bacterial DNA methylome. Here, we leveraged single-molecule, real-time sequencing (SMRT-seq) to examine the m