Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Jeffrey S, Willey"'
Autor:
Isabel R. Barnet, Shannon R. Emerzian, Ramina Behzad, Daniel J. Brooks, Trinity Tedtsen, Marcela Granados, Sun Park, Joseph Moore, John D. Olson, Lamya Karim, Mary L. Bouxsein, J. Mark Cline, Jeffrey S. Willey
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Exposure to ionizing radiation for oncological therapy increases the risk for late-onset fractures in survivors. However, the effects of total body irradiation (TBI) on adult bone are not well-characterized. The primary aim of this study was
Externí odkaz:
https://doaj.org/article/df3ebdabc72b4be6b523528734f4c0e3
Autor:
Jacob Raber, Mitali Chaudhari, Alexis De la Torre, Sarah Holden, Kat Kessler, Breanna Glaeser, Marek Lenarczyk, Scott Willem Leonard, Alexander Borg, Andy Kwok, Chirayu Patel, Amy Kronenberg, Christopher M. Olsen, Jeffrey S. Willey, Jeffrey Morré, Jaewoo Choi, Jan Frederik Stevens, Gerd Bobe, Jessica Minnier, John Baker
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
IntroductionEffects and interactions between different spaceflight stressors are expected to be experienced by crew on missions when exposed to microgravity and galactic cosmic rays (GCRs). One of the limitations of previous studies on simulated weig
Externí odkaz:
https://doaj.org/article/2dec1e3601ec4a3796d0c67f4ecd7326
Autor:
Jacob Raber, Sarah Holden, Kat Kessler, Breanna Glaeser, Chloe McQuesten, Mitali Chaudhari, Fiona Stenzel, Marek Lenarczyk, Scott Willem Leonard, Jeffrey Morré, Jaewoo Choi, Amy Kronenberg, Alexander Borg, Andy Kwok, Jan Frederik Stevens, Christopher Olsen, Jeffrey S. Willey, Gerd Bobe, Jessica Minnier, John E. Baker
Publikováno v:
Frontiers in Physiology, Vol 14 (2024)
Introduction: The space environment astronauts experience during space missions consists of multiple environmental challenges, including microgravity. In this study, we assessed the behavioral and cognitive performances of male Fisher rats 2 months a
Externí odkaz:
https://doaj.org/article/1bb6f8739e9d45ff9ac8c715fc29053f
Characterization of gene expression profiles in the mouse brain after 35 days of spaceflight mission
Autor:
Jacob M. Holley, Seta Stanbouly, Michael J. Pecaut, Jeffrey S. Willey, Michael Delp, Xiao Wen Mao
Publikováno v:
npj Microgravity, Vol 8, Iss 1, Pp 1-10 (2022)
Abstract It has been proposed that neuroinflammatory response plays an important role in the neurovascular remodeling in the brain after stress. The goal of the present study was to characterize changes in the gene expression profiles associated with
Externí odkaz:
https://doaj.org/article/fc38a452cfec4318834d8572d8d3e102
Autor:
Jeffrey S. Willey, Serena Aunon-Chancellor, Lauren A. Miles, Joseph E. Moore, Xiao W. Mao, Robert W. Wallace, Matthew C. Foy
Publikováno v:
npj Microgravity, Vol 8, Iss 1, Pp 1-3 (2022)
Abstract Alpha(α)Klotho, a soluble transmembrane protein, facilitates calcium-phosphorus homeostasis through feedback between bone and kidney and is a potential systemic biomarker for bone-kidney health during spaceflight. We determined if: (1) plas
Externí odkaz:
https://doaj.org/article/41dd8fe159e248759815a4acb2bfd279
Autor:
Andy T. Kwok, Nequesha S. Mohamed, Johannes F. Plate, Raghunatha R. Yammani, Samuel Rosas, Ted A. Bateman, Eric Livingston, Joseph E. Moore, Bethany A. Kerr, Jingyun Lee, Cristina M. Furdui, Li Tan, Mary L. Bouxsein, Virginia L. Ferguson, Louis S. Stodieck, David C. Zawieja, Michael D. Delp, Xiao W. Mao, Jeffrey S. Willey
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Reduced knee weight-bearing from prescription or sedentary lifestyles are associated with cartilage degradation; effects on the meniscus are unclear. Rodents exposed to spaceflight or hind limb unloading (HLU) represent unique opportunities
Externí odkaz:
https://doaj.org/article/e20ccc74580a4e1287b71ce54f1f7858
Autor:
Jacob Raber, Sarah Holden, Reetesh Sudhakar, Reed Hall, Breanna Glaeser, Marek Lenarczyk, Kristen Rockwell, Natalie Nawarawong, Jennifer Sterrett, Ruby Perez, Scott William Leonard, Jeffrey Morré, Jaewoo Choi, Amy Kronenberg, Alexander Borg, Andy Kwok, Jan Frederik Stevens, Christopher M. Olsen, Jeffrey S. Willey, Gerd Bobe, John Baker
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
A limitation of simulated space radiation studies is that radiation exposure is not the only environmental challenge astronauts face during missions. Therefore, we characterized behavioral and cognitive performance of male WAG/Rij rats 3 months after
Externí odkaz:
https://doaj.org/article/0574366066554b75894e103ed10b7df6
Changes in ionizing radiation dose rate affect cell cycle progression in adipose derived stem cells.
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0250160 (2021)
Biomedical use of radiation is utilized in effective diagnostic and treatment tools, yet can introduce risks to healthy tissues. High energy photons used for diagnostic purposes have high penetration depth and can discriminate multiple tissues based
Externí odkaz:
https://doaj.org/article/c1bd9c6406004e4ba1af90414495bca5
Autor:
T David Luo, Alejandro Marquez-Lara, Zachary K Zabarsky, Jeremy B Vines, Katie C Mowry, Alexander H Jinnah, Xue Ma, Benjamin W Berwick, Jeffrey S Willey, Zhongyu Li, Thomas L Smith, Tadhg J O’Gara
Publikováno v:
Journal of Orthopaedic Surgery, Vol 26 (2018)
Purpose: Various animal models have been proposed to mimic the pathophysiologic process of intervertebral disc degeneration, a leading cause of back pain. The purpose of this study is to describe a minimally invasive technique via percutaneous needle
Externí odkaz:
https://doaj.org/article/72d16045a7fd4e2981f9c6ae4b3c1374
Autor:
Wayne D. Newhauser, Jacqueline P. Williams, Michael A. Noska, Caridad Borrás, E. Vincent Holahan, Shaheen A. Dewji, Thomas E. Johnson, Jerry W. Hiatt, John W. Poston, Nolan Hertel, Dustin A. Gress, Michael D. Mills, David W. Jordan, Steven G. Sutlief, Melissa C. Martin, Edward Jackson, Edward I. Bluth, Donald P. Frush, M. Elizabeth Oates, Jeanne LaBerge, Hubert Y. Pan, Seth A. Rosenthal, Lawrence W. Townsend, Lori Brady, Janice Lindegard, Howard L. Hall, Elizabeth McAndrew‐Benavides, Eric Abelquist, Mitchell S. Anscher, Marcelo Vazquez, Amy Kronenberg, Jeffrey S. Willey, Theodore Lawrence, Gayle E. Woloschak, Brian Marples, Rosemary Wong, Michael Story, Roger W. Howell, Tom K. Hei, Sergey Y. Tolmachev, John D. Auxier, Thomas L. Rucker, Mikael Nilsson, Ralf Sudowe, Brian A. Powell, Mark P. Jensen
Publikováno v:
Journal of Applied Clinical Medical Physics. 23