Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Jeffrey S, Thinschmidt"'
Autor:
Jeffrey S. Thinschmidt, Scott W. Harden, Michael A. King, James D. Talton, Charles J. Frazier
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
We established a novel brain slice assay to test the ability of acetylcholinesterase (AChE) reactivators to prevent ACh-induced M1 muscarinic acetylcholine receptor (mAChR) dependent hyperexcitability observed after exposure to the organophosphate (O
Externí odkaz:
https://doaj.org/article/3545c7d60f87475388b0638bb2d7565a
Autor:
Jeffrey S, Thinschmidt, Scott W, Harden, Michael A, King, James D, Talton, Charles J, Frazier
Publikováno v:
Frontiers in cellular neuroscience. 16
We established a novel brain slice assay to test the ability of acetylcholinesterase (AChE) reactivators to prevent ACh-induced M1 muscarinic acetylcholine receptor (mAChR) dependent hyperexcitability observed after exposure to the organophosphate (O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a0c0019a3170b82e68bdf4e2747f9678
https://pubmed.ncbi.nlm.nih.gov/36479275
https://pubmed.ncbi.nlm.nih.gov/36479275
Autor:
Yalun Tan, Scott W Harden, Marcelo Febo, Luis M. Colon-Perez, Karlena M. Cahill, Sarthak Singhal, Jeffrey S. Thinschmidt, Todd J. Sahagian, Eric G. Krause, Annette D. de Kloet, Charles J. Frazier, Dan-Tam M. Nguyen
Publikováno v:
The Journal of Neuroscience. 39:3249-3263
Social recognition, the ability to recognize individuals that were previously encountered, requires complex integration of sensory inputs with previous experience. Here, we use a variety of approaches to discern how oxytocin-sensitive neurons in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e78efbeaf919c376d31a733490dd6ba
https://doi.org/10.1523/jneurosci.2944-18.2019
https://doi.org/10.1523/jneurosci.2944-18.2019
Autor:
Marcelo Febo, Michael A. King, Maria B. Grant, Fletcher A. White, Sergio Caballero, Luis M. Colon-Perez, Jeffrey S. Thinschmidt
Publikováno v:
Neuroscience Letters. 615:21-27
We recently found indicators of hypothalamic inflammation and neurodegeneration linked to the loss of neuroprotective factors including insulin-like growth factor (IGF-1) and IGF binding protein-2 (IGFBP-3) in mice made diabetic using streptozotocin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b0fd719af513eeea1f87d474520e82d
https://doi.org/10.1016/j.neulet.2016.01.014
https://doi.org/10.1016/j.neulet.2016.01.014
Autor:
Ana Leda F. Longhini, Michael E. Boulton, Jeffrey S. Thinschmidt, Maria B. Grant, Michael A. King
Publikováno v:
Diabetes. 67
Purpose: Since loss of retinal SST and circulating SST occurs in DR, we asked if loss of hypothalamic SST production would impact the innervation and function of the BM and influence DR in T2D rat model. Methods: Brain sections of BBZ/Wor rats with 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::886959b55052e45d19c2bbfd3c1be5c0
https://doi.org/10.2337/db18-238-or
https://doi.org/10.2337/db18-238-or
Autor:
Louise Cole, Tailoi Chan-Ling, Maria B. Grant, Sergio Caballero, Samuel J. Adamson, Ping Hu, Jeffrey S. Thinschmidt
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 308:E688-E698
Neuroinflammation and neurodegeneration have been observed in the brain in type 1 diabetes (T1D). However, little is known about the mediators of these effects. In T1D mice with 12- and 35-wk duration of diabetes we examined two mechanisms of neurode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddc6e2030f26275ab39b069c4b7cc1e5
https://doi.org/10.1152/ajpendo.00504.2014
https://doi.org/10.1152/ajpendo.00504.2014
Autor:
Ping Hu, Lynn C Shaw, Ashay D. Bhatwadekar, Sameer P. Leley, Sergio Caballero, Maria Korah, Maria B. Grant, Yaqian Duan, Jeffrey S. Thinschmidt, Julia V. Busik
Publikováno v:
Vision research. 139
The widespread nature of diabetes affects all organ systems of an individual including the bone marrow. Long-term damage to the cellular and extracellular components of the bone marrow leads to a rapid decline in the bone marrow-hematopoietic stem/pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::424b8c5be8a73644e2e7e79ef7dc6355
https://pubmed.ncbi.nlm.nih.gov/29042190
https://pubmed.ncbi.nlm.nih.gov/29042190
Autor:
Jeffrey S. Thinschmidt, Aaron C. Hirko, Jeffrey A. Hughes, Michael A. King, Zhimin Li, Huong L. Moldthan, Ahmed S. Elshikha, Joanna Peris, Maria B. Grant, Yuanqing Lu, Sihong Song
Publikováno v:
Journal of Stroke and Cerebrovascular Diseases. 23:e355-e363
Currently, the only effective therapy for acute ischemic stroke is the thrombolytic agent recombinant tissue plasminogen activator. α1-Antitrypsin, an endogenous inhibitor of serine proteinases and a primary acute phase protein with potent anti-infl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::400c916a2f60b1c4419d7c4eb3d63afb
https://doi.org/10.1016/j.jstrokecerebrovasdis.2013.12.029
https://doi.org/10.1016/j.jstrokecerebrovasdis.2013.12.029
Autor:
Tailoi Chan-Ling, Sergio Caballero, Julia V. Busik, Yuanqing Yan, Jeffrey S. Thinschmidt, Sugata Hazra, Andrea Zsombok, Andrei V. Derbenev, Jaleel A. Miyan, Wencheng Li, Daniel R. Saban, Ping Hu, Maria Tikhonenko, Tatiana Salazar, Mohan K. Raizada, James M. Dominguez, Ashay D Bhatwadekar, Michael E. Boulton, Maria B. Grant, Susan P. McGorray
Publikováno v:
The American Journal of Pathology. 183(5):1608-1620
By using pseudorabies virus expressing green fluorescence protein, we found that efferent bone marrow-neural connections trace to sympathetic centers of the central nervous system in normal mice. However, this was markedly reduced in type 1 diabetes,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6056c88d0fce9f6ea5a67ba47c98f03a
Autor:
Lynn C. Shaw, Xiaoping Qi, Michael E. Boulton, Jeffrey S. Thinschmidt, Matthew B. Neu, Ashay D Bhatwadekar, Julia V. Busik, Choogon Lee, James M. Dominiguez, Yuanqing Yan, Sergio Li Calzi, Maria B. Grant
Publikováno v:
Diabetes
In this study, we assessed whether Per2 clock gene–mutant mice exhibit a vascular phenotype similar to diabetes. Per2 (B6.129-Per2tm1Drw/J) or wild-type control mice 4 and 12 months of age were used. To evaluate diabetes-like phenotype in Per2 muta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7721a32be6d107db8e3f36efd1d59b4
https://doi.org/10.2337/db12-0172
https://doi.org/10.2337/db12-0172