Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Jeffrey S, Kavanaugh"'
Autor:
Lisanne de Vor, Bruce van Dijk, Kok van Kessel, Jeffrey S Kavanaugh, Carla de Haas, Piet C Aerts, Marco C Viveen, Edwin C Boel, Ad C Fluit, Jakub M Kwiecinski, Gerard C Krijger, Ruud M Ramakers, Freek J Beekman, Ekaterina Dadachova, Marnix GEH Lam, H Charles Vogely, Bart CH van der Wal, Jos AG van Strijp, Alexander R Horswill, Harrie Weinans, Suzan HM Rooijakkers
Publikováno v:
eLife, Vol 11 (2022)
Implant-associated Staphylococcus aureus infections are difficult to treat because of biofilm formation. Bacteria in a biofilm are often insensitive to antibiotics and host immunity. Monoclonal antibodies (mAbs) could provide an alternative approach
Externí odkaz:
https://doaj.org/article/f9dfe179409a4ffabf19a218bc324d32
Autor:
Morgan L. Grundstad, Corey P. Parlet, Jakub M. Kwiecinski, Jeffrey S. Kavanaugh, Heidi A. Crosby, Young-Saeng Cho, Kristopher Heilmann, Daniel J. Diekema, Alexander R. Horswill
Publikováno v:
mSphere, Vol 4, Iss 4 (2019)
ABSTRACT Methicillin-resistant Staphylococcus aureus (MRSA) infections impact all patient populations both in the community and in health care settings. Despite advances in our knowledge of MRSA virulence, little is known about the regulatory mechani
Externí odkaz:
https://doaj.org/article/0a24134852d24219b10c590d69fc61ab
Autor:
Jeffrey S. Kavanaugh, Caralyn E. Flack, Jessica Lister, Erica B. Ricker, Carolyn B. Ibberson, Christian Jenul, Derek E. Moormeier, Elizabeth A. Delmain, Kenneth W. Bayles, Alexander R. Horswill
Publikováno v:
mBio, Vol 10, Iss 3 (2019)
ABSTRACT We developed a new approach that couples Southwestern blotting and mass spectrometry to discover proteins that bind extracellular DNA (eDNA) in bacterial biofilms. Using Staphylococcus aureus as a model pathogen, we identified proteins with
Externí odkaz:
https://doaj.org/article/a8e208da8e384b019ca1c75e6293f2c3
Autor:
Corey P. Parlet, Jeffrey S. Kavanaugh, Heidi A. Crosby, Huzefa A. Raja, Tamam El-Elimat, Daniel A. Todd, Cedric J. Pearce, Nadja B. Cech, Nicholas H. Oberlies, Alexander R. Horswill
Publikováno v:
Cell Reports, Vol 27, Iss 1, Pp 187-198.e6 (2019)
Summary: Recurrent epidemics of drug-resistant Staphylococcus aureus illustrate the rapid lapse of antibiotic efficacy following clinical implementation. Over the last decade, community-associated methicillin-resistant S. aureus (MRSA) has emerged as
Externí odkaz:
https://doaj.org/article/012edc5e93ba4942bdd4d3fc2762ac41
Autor:
Rebecca A, Keogh, Amanda L, Haeberle, Christophe J, Langouët-Astrié, Jeffrey S, Kavanaugh, Eric P, Schmidt, Garrett D, Moore, Alexander R, Horswill, Kelly S, Doran
Publikováno v:
Science advances. 8(45)
Diabetic wounds have poor healing outcomes due to the presence of numerous pathogens and a dysregulated immune response. Group B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e49ede3541003570fa4cbdfa78b74c8f
https://pubmed.ncbi.nlm.nih.gov/36367946
https://pubmed.ncbi.nlm.nih.gov/36367946
Autor:
Rebecca A. Keogh, Amanda L. Haeberle, Christophe J. Langouët-Astrié, Jeffrey S. Kavanaugh, Eric P. Schmidt, Garrett D. Moore, Alexander R. Horswill, Kelly S. Doran
Publikováno v:
Science Advances. 8
Diabetic wounds have poor healing outcomes due to the presence of numerous pathogens and a dysregulated immune response. Group BStreptococcus(GBS) is commonly isolated from diabetic wound infections, but the mechanisms of GBS virulence during these i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5eb4c63bed32640c02a4c8c7ec73ab5
https://doi.org/10.1126/sciadv.add3221
https://doi.org/10.1126/sciadv.add3221
Autor:
Jeffrey S. Kavanaugh, Lihua Xie, Jessica S. Hook, Alexander R. Horswill, Jessica G. Moreland, Aidan O'Malley, Parth A Patel
Publikováno v:
The Journal of Immunology. 207:966-973
Neutrophils, polymorphonuclear leukocytes (PMN), play a critical role in the innate immune response to Staphylococcus aureus, a pathogen that continues to be associated with significant morbidity and mortality. Neutrophil extracellular trap (NET) for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1d4a5fa083e1678ac850f3e59c16714
https://doi.org/10.4049/jimmunol.2100283
https://doi.org/10.4049/jimmunol.2100283
Group B Streptococcus Adaptation Promotes Survival in a Hyperinflammatory Diabetic Wound Environment
Autor:
Rebecca A. Keogh, Amanda L. Haeberle, Christophe J. Langouët-Astrié, Jeffrey S. Kavanaugh, Eric P. Schmidt, Garrett D. Moore, Alexander R. Horswill, Kelly S. Doran
Diabetic wounds have poor healing outcomes due to the presence of numerous pathogens and a dysregulated immune response. Group BStreptococcus(GBS) is commonly isolated from diabetic wound infections, but the mechanisms of GBS virulence during these i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fb3924847c8822eb39be983146a2fc7
https://doi.org/10.1101/2022.06.27.497804
https://doi.org/10.1101/2022.06.27.497804
Autor:
Andrew S. Haynes, Andrea Prinzi, Lori J. Silveira, Sarah K. Parker, Jed N. Lampe, Jeffrey S. Kavanaugh, Alexander R. Horswill, Douglas Fish
Publikováno v:
Microbiology spectrum. 10(4)
Cephalexin and cefadroxil are oral first-generation cephalosporins used to treat methicillin-susceptible Staphylococcus aureus (MSSA) infections. Despite its shorter half-life, cephalexin is more frequently prescribed, although cefadroxil is an appea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa25fb097597557cdc2f29a60de8f7a6
https://pubmed.ncbi.nlm.nih.gov/35730963
https://pubmed.ncbi.nlm.nih.gov/35730963
Autor:
Christophe Langouët-Astrié, Kaori Oshima, Sarah A. McMurtry, Yimu Yang, Jakub M. Kwiecinski, Wells B. LaRivière, Jeffrey S. Kavanaugh, Igor Zakharevich, Kirk C. Hansen, Deling Shi, Fuming Zhang, Kristina M. Boguslawski, Sofya S. Perelman, Gouwei Su, Victor J. Torres, Jian Liu, Alexander R. Horswill, Eric P. Schmidt
Publikováno v:
Cell reports. 41(9)
Influenza infection is substantially worsened by the onset of secondary pneumonia caused by bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA). The bidirectional interaction between the influenza-injured lung microenvironment and MR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c76a3ec94ba78c8f0f826b3cebf8fa0
https://pubmed.ncbi.nlm.nih.gov/36450248
https://pubmed.ncbi.nlm.nih.gov/36450248