Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Jeffrey R. Vieregg"'
Polyelectrolyte complex micelles (PCMs) are widely used in the delivery of hydrophilic payloads. Their attractive features include an ability to tune physical attributes, which are strongly dependent on the size and chemical structure of each polymer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bb4491695bef7889f90f51750cce21a
https://doi.org/10.26434/chemrxiv.13721719.v1
https://doi.org/10.26434/chemrxiv.13721719.v1
Publikováno v:
Journal of Visualized Experiments.
Polyelectrolyte complex micelles (PCMs), core-shell nanoparticles formed by self-assembly of charged polymers in aqueous solution, provide a powerful platform for exploring the physics of polyelectrolyte interactions and also offer a promising soluti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24fef5677c67c70c9abf29f4b34bbc1b
https://doi.org/10.3791/60894-v
https://doi.org/10.3791/60894-v
Publikováno v:
Nano Letters. 18:7111-7117
Polyelectrolyte complex micelles (PCMs), nanoparticles formed by electrostatic self-assembly of charged polymers with charged-neutral hydrophilic block copolymers, offer a potential solution to the challenging problem of delivering therapeutic nuclei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7461bcf7bb2fb639a6d87608c66535a7
https://doi.org/10.1021/acs.nanolett.8b03132
https://doi.org/10.1021/acs.nanolett.8b03132
Autor:
Jeffrey R. Vieregg, T-Y Dora Tang
Publikováno v:
Current Opinion in Colloid & Interface Science. 26:50-57
In this review, we examine the interaction of nucleic acids with cell-like structures based on liquid–liquid phase separation of charged molecules (complex coacervation) and amphiphilic self-assembly (lipid vesicles). We discuss the mechanisms of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31596dbe763c2e8e59c816c2d09df79a
https://doi.org/10.1016/j.cocis.2016.09.004
https://doi.org/10.1016/j.cocis.2016.09.004
Publikováno v:
Polymers
Polymers, Vol 11, Iss 1, p 83 (2019)
Volume 11
Issue 1
Polymers, Vol 11, Iss 1, p 83 (2019)
Volume 11
Issue 1
Polyelectrolyte complex micelles (PCMs, core-shell nanoparticles formed by complexation of a polyelectrolyte with a polyelectrolyte-hydrophilic neutral block copolymer) offer a solution to the critical problem of delivering therapeutic nucleic acids,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf55acea27c9f65969b9c1f4073278f8
http://europepmc.org/articles/PMC6402004
http://europepmc.org/articles/PMC6402004
Autor:
Jeffrey R. Vieregg, Alex J. Bologna, Michael Lueckheide, Lorraine Leon, Josean Reyes Rivera, Matthew Tirrell, Amanda B. Marciel
Publikováno v:
Journal of the American Chemical Society. 140(5)
When oppositely charged polymers are mixed, counterion release drives phase separation; understanding this process is a key unsolved problem in polymer science and biophysical chemistry, particularly for nucleic acids, polyanions whose biological fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9eb2602a407e63e10260e3b95dc33cc
https://pubmed.ncbi.nlm.nih.gov/29314832
https://pubmed.ncbi.nlm.nih.gov/29314832
Publikováno v:
PDA journal of pharmaceutical science and technology. 72(1)
For many years, glass has been the default material for parenteral packaging, but the development of advanced plastics such as cyclic olefin polymers and the rapidly increasing importance of biologic drugs have provided new choices, as well as more s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e79e00a0eb84abf6d863dd243bee55f9
https://pubmed.ncbi.nlm.nih.gov/28928291
https://pubmed.ncbi.nlm.nih.gov/28928291
Publikováno v:
Journal of the American Chemical Society
Nucleic acid probes are used for diverse applications in vitro, in situ, and in vivo. In any setting, their power is limited by imperfect selectivity (binding of undesired targets) and incomplete affinity (binding is reversible, and not all desired t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9554905b5536a1ded377cbd88ed94bc
https://doi.org/10.1021/ja4009216
https://doi.org/10.1021/ja4009216
Publikováno v:
Journal of the American Chemical Society. 129:14966-14973
Using optical tweezers, we have measured the effect of monovalent cation concentration and species on the folding free energy of five large (49-124 nt) RNA hairpins, including HIV-1 TAR and molecules approximating A.U and G.C homopolymers. RNA second
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8302d8018eb4e3690e8f660e27169171
https://doi.org/10.1021/ja074809o
https://doi.org/10.1021/ja074809o
Publikováno v:
Biophysical Journal. 108(2)
Recent years have seen an explosion in our appreciation of the myriad roles that RNA plays in the cell, including the discovery of new classes of regulatory RNAs such as long non-coding RNAs (lncRNAs). The three-dimensional folded structure of many c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dadcb6f2abbcc451dc3326c2ef4097d2