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of 6
pro vyhledávání: '"Jeffrey R. Atkinson"'
Autor:
Jeffrey R. Atkinson, Andrew D. Jerome, Andrew R. Sas, Ashley Munie, Cankun Wang, Anjun Ma, William D. Arnold, Benjamin M. Segal
Publikováno v:
JCI Insight, Vol 7, Iss 12 (2022)
Biological aging is the strongest factor associated with the clinical phenotype of multiple sclerosis (MS). Relapsing-remitting MS typically presents in the third or fourth decade, whereas the mean age of presentation of progressive MS (PMS) is 45 ye
Externí odkaz:
https://doaj.org/article/4f165570f80b4ba093256f26b8cce951
Autor:
Andrew D. Jerome, Jeffrey R. Atkinson, Arnetta L. McVey Moffatt, Jesse A. Sepeda, Benjamin M. Segal, Andrew R. Sas
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Recent studies using advanced techniques such as single cell RNA sequencing (scRNAseq), high parameter flow cytometry, and proteomics reveal that neutrophils are more heterogeneous than previously appreciated. Unique subsets have been identified in t
Externí odkaz:
https://doaj.org/article/47910c21c22049b8a75bcb33e112601f
Autor:
Ashley Munie Gardner, Jeffrey R. Atkinson, Nicole M. Wilkinson, Andrew D. Jerome, Calli E. Bellinger, Andrew R. Sas, Benjamin M. Segal
Experimental autoimmune encephalomyelitis (EAE), induced by the adoptive transfer of Th17 cells, typically presents with ascending paralysis and inflammatory demyelination of the spinal cord. Brain white matter is relatively spared. Here we show that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c6e74ee7035f9f4d6156db94991866c
https://doi.org/10.2139/ssrn.4265668
https://doi.org/10.2139/ssrn.4265668
Publikováno v:
J Immunol
Multiple sclerosis (MS), a neuroinflammatory disease that affects millions worldwide, is widely thought to be autoimmune in etiology. Historically, research into MS pathogenesis has focused on autoreactive CD4 T cells because of their critical role i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::067e4fae744032224da797a12d0df588
https://pubmed.ncbi.nlm.nih.gov/33443060
https://pubmed.ncbi.nlm.nih.gov/33443060
Publikováno v:
Journal of Virology
The prevalence and role of antigen-specific Bmem in the CNS during viral encephalomyelitis is largely undefined. A lack of reliable markers identifying murine Bmem has made it difficult to assess their contribution to local antiviral protection via a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a58be20ea12aad2ec4144d5e11414482
Publikováno v:
Journal of Virology
B cell subsets with phenotypes characteristic of naive, non-isotype-switched, memory (B mem ) cells and antibody-secreting cells (ASC) accumulate in various models of central nervous system (CNS) inflammation, including viral encephalomyelitis. Durin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05da3c330790bdeb63e46564b5b5d9a5
https://doi.org/10.1128/jvi.01352-17
https://doi.org/10.1128/jvi.01352-17