Zobrazeno 1 - 10
of 291
pro vyhledávání: '"Jeffrey R Fineman"'
Autor:
Jason Boehme, Natacha Le Moan, Rebecca J Kameny, Alexandra Loucks, Michael J Johengen, Amy L Lesneski, Wenhui Gong, Brian D Goudy, Tina Davis, Kevin Tanaka, Andrew Davis, Youping He, Janel Long-Boyle, Vijay Ivaturi, Jogarao V S Gobburu, Jonathan A Winger, Stephen P Cary, Sanjeev A Datar, Jeffrey R Fineman, Ana Krtolica, Emin Maltepe
Publikováno v:
PLoS Biology, Vol 17, Iss 1, p e3000119 (2019)
[This corrects the article DOI: 10.1371/journal.pbio.2005924.].
Externí odkaz:
https://doaj.org/article/eac3c42183f74da5877f5fc5b371e190
Autor:
Jason Boehme, Natacha Le Moan, Rebecca J Kameny, Alexandra Loucks, Michael J Johengen, Amy L Lesneski, Wenhui Gong, Brian D. Goudy, Tina Davis, Kevin Tanaka, Andrew Davis, Youping He, Janel Long-Boyle, Vijay Ivaturi, Jogarao V S Gobburu, Jonathan A Winger, Stephen P Cary, Sanjeev A Datar, Jeffrey R Fineman, Ana Krtolica, Emin Maltepe
Publikováno v:
PLoS Biology, Vol 16, Iss 10, p e2005924 (2018)
The heart exhibits the highest basal oxygen (O2) consumption per tissue mass of any organ in the body and is uniquely dependent on aerobic metabolism to sustain contractile function. During acute hypoxic states, the body responds with a compensatory
Externí odkaz:
https://doaj.org/article/e13aa0d7d62a4167b657b0418bb3eb3f
Autor:
Olga Rafikova, Mary L Meadows, Jason M Kinchen, Robert P Mohney, Emin Maltepe, Ankit A Desai, Jason X-J Yuan, Joe G N Garcia, Jeffrey R Fineman, Ruslan Rafikov, Stephen M Black
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150480 (2016)
There is increasing interest in the potential for metabolic profiling to evaluate the progression of pulmonary hypertension (PH). However, a detailed analysis of the metabolic changes in lungs at the early stage of PH, characterized by increased pulm
Externí odkaz:
https://doaj.org/article/55c5de473c2c4faaa18587933f9f342c
Autor:
Shruti Sharma, Xutong Sun, Ruslan Rafikov, Sanjiv Kumar, Yali Hou, Peter E Oishi, Sanjeev A Datar, Gary Raff, Jeffrey R Fineman, Stephen M Black
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e41555 (2012)
ObjectiveCarnitine homeostasis is disrupted in lambs with endothelial dysfunction secondary to increased pulmonary blood flow (Shunt). Our recent studies have also indicated that the disruption in carnitine homeostasis correlates with a decrease in P
Externí odkaz:
https://doaj.org/article/a79e930a075b47b2a8661612db632d90
Autor:
Michael A. Smith, Geoffrey Cheng, Rachel Phelan, Ruta Brazauskas, Joelle Strom, Kwang Woo Ahn, Betty Ky Hamilton, Andrew Peterson, Bipin Savani, Hélène Schoemans, Michelle L. Schoettler, Mohamed Sorror, Roberta L. Keller, Christine S. Higham, Christopher C. Dvorak, Jeffrey R. Fineman, Matt S. Zinter
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
ObjectiveTo determine the incidence, risk factors, and outcomes of pulmonary hypertension (PH) in the pediatric intensive care unit (PICU) after pediatric hematopoietic stem cell transplant (HCT).MethodsThis was a retrospective study of pediatric pat
Externí odkaz:
https://doaj.org/article/c2dcb6b7c66d4abe84bcd91fc9b88d90
Autor:
Emily Morell, Elizabeth Colglazier, Jasmine Becerra, Leah Stevens, Martina A. Steurer, Anshuman Sharma, Hung Nguyen, Irfan S. Kathiriya, Stephen Weston, David Teitel, Roberta Keller, Elena K. Amin, Hythem Nawaytou, Jeffrey R. Fineman
Publikováno v:
Pulmonary Circulation, Vol 14, Iss 2, Pp n/a-n/a (2024)
Abstract Cardiac catheterization remains the gold standard for the diagnosis and management of pediatric pulmonary hypertension (PH). There is lack of consensus regarding optimal anesthetic and airway regimen. This retrospective study describes the a
Externí odkaz:
https://doaj.org/article/d29abfe687d84f25b35c00ab08767704
Autor:
Marissa D. Pokharel, Alejandro Garcia-Flores, David Marciano, Maria C. Franco, Jeffrey R. Fineman, Saurabh Aggarwal, Ting Wang, Stephen M. Black
Publikováno v:
Redox Biology, Vol 70, Iss , Pp 103049- (2024)
Once thought of in terms of bioenergetics, mitochondria are now widely accepted as both the orchestrator of cellular health and the gatekeeper of cell death. The pulmonary disease field has performed extensive efforts to explore the role of mitochond
Externí odkaz:
https://doaj.org/article/ca0f8236e2604227a1b3d514218b84a6
This open access book focuses on the molecular mechanism of congenital heart disease and pulmonary hypertension, offering new insights into the development of pulmonary circulation and the ductus arteriosus. It describes in detail the molecular mecha
Autor:
Joseph M. Collaco, Steven H. Abman, Eric D. Austin, Catherine M. Avitabile, Angela Bates, Jeffrey R. Fineman, Grace A. Freire, Stephanie S. Handler, Dunbar D. Ivy, Usha S. Krishnan, Mary P. Mullen, Nidhy P. Varghese, Delphine Yung, Melanie K. Nies, Allen D. Everett, Kanecia O. Zimmerman, William Simmons, Hrishikesh Chakraborty, Gayane Yenokyan, Allison Newell‐Sturdivant, Eric Christensen, Lindsay M. Eyzaguirre, Daniel F. Hanley, Erika B. Rosenzweig, Lewis H. Romer
Publikováno v:
Pulmonary Circulation, Vol 13, Iss 4, Pp n/a-n/a (2023)
Abstract Pulmonary hypertension (PH) is a significant health problem that contributes to high morbidity and mortality in diverse cardiac, pulmonary, and systemic diseases in children. Evidence‐based advances in PH care have been challenged by a pau
Externí odkaz:
https://doaj.org/article/e4055b6fcb9148eeae29660762851c72
Autor:
Marissa D. Pokharel, David P. Marciano, Panfeng Fu, Maria Clara Franco, Hoshang Unwalla, Kim Tieu, Jeffrey R. Fineman, Ting Wang, Stephen M. Black
Publikováno v:
Redox Biology, Vol 64, Iss , Pp 102797- (2023)
Mitochondria are highly dynamic organelles essential for cell metabolism, growth, and function. It is becoming increasingly clear that endothelial cell dysfunction significantly contributes to the pathogenesis and vascular remodeling of various lung
Externí odkaz:
https://doaj.org/article/5481895c4f834230aa1ddd24f67cf8a7