Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jeffrey P. Novack"'
Autor:
Jeffrey P. Novack
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Case-based, interactive sessions for small groups (in a large medical school class of 150 students) reinforces basic immunology concepts by including clinical scenarios that stimulate student learning and consolidate critical concepts. Careful design
Externí odkaz:
https://doaj.org/article/f9b625ad0fa640ad8fcbe457f9af31ae
Publikováno v:
Trends in Immunology
Ubc13-catalyzed K63 ubiquitination is a major control point for immune signaling. Recent evidence has shown that the control of multiple immune functions, including chronic inflammation, pathogen responses, lymphocyte activation, and regulatory signa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d63388de8737fa81c409656330cb7f9b
https://doi.org/10.1016/j.it.2021.12.005
https://doi.org/10.1016/j.it.2021.12.005
Autor:
Jeffrey P. Novack
Publikováno v:
Journal of Restorative Medicine. 6:3-18
Progressive neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease are a major public health burden. Neurodegenerative diseases have a common pathophysiology of protein aggregate formation but the exact mechanism of neuron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99fa4972614c45a895259bc7ef35b5e7
https://doi.org/10.14200/jrm.2017.6.0102
https://doi.org/10.14200/jrm.2017.6.0102
Publikováno v:
Fitoterapia. 81:914-919
Woody fungi and yeast preparations show promise in cancer treatment by activating anti-tumor immune responses. Macrophages (J774A.1) were treated with PSK, Reishi extract, scleroglucan or vehicle control. Pre-incubation with TLR4 blocking antibody in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c6a0a0cbc813b294fdd33b901fa8b78
https://doi.org/10.1016/j.fitote.2010.06.002
https://doi.org/10.1016/j.fitote.2010.06.002
Autor:
J. K. Bentley, Harry Charbonneau, Dalia Seger, William K. Sonnenburg, Ann Kadlecek, Jeffrey P. Novack, C H Sherbert, J A Beavo
Publikováno v:
Scopus-Elsevier
Partially degenerate oligonucleotides based on peptide sequence were used to isolate cDNA to a 63-kDa bovine brain calmodulin-stimulated phosphodiesterase (CaM-PDE) isozyme. A 412-base pair polymerase chain reaction fragment was obtained and used alo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57c712ed0ebf9d11f0561e2601c3c383
https://doi.org/10.1016/s0021-9258(19)37014-0
https://doi.org/10.1016/s0021-9258(19)37014-0
Autor:
Jeffrey P. Novack, Santosh Kumar, Donald K. Blumenthal, Donald F. Hunt, Harry Charbonneau, Jeffrey Shabanowitz, Kenneth A. Walsh, Joseph A. Beavo, Patrick R. Griffin
Publikováno v:
Biochemistry. 30(32)
The complete amino acid sequence of the 61-kDa calmodulin-dependent, cyclic nucleotide phosphodiesterase (CaM-PDE) from bovine brain has been determined. The native protein is a homodimer of N alpha-acetylated, 529-residue polypeptide chains, each of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0cd494934c574da2d3bc67f9a8deb66
https://pubmed.ncbi.nlm.nih.gov/1651111
https://pubmed.ncbi.nlm.nih.gov/1651111
Publikováno v:
Biochemistry. 30(32)
Partial protein sequences from the 59-kDa bovine heart and the 63-kDa bovine brain calmodulin-dependent phosphodiesterases (CaM-PDEs) were determined and compared to the sequence of the 61-kDa isozyme reported by Charbonneau et al. [Charbonneau, H.,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee1db94348f1513d0add7e8dcc9f954f
https://pubmed.ncbi.nlm.nih.gov/1651112
https://pubmed.ncbi.nlm.nih.gov/1651112
Autor:
Joseph A. Beavo, Harry Charbonneau, Donald K. Blumenthal, Jeffrey P. Novack, Kenneth A. Walsh
Publikováno v:
Calcium Protein Signaling ISBN: 9781468456813
The calmodulin-dependent cyclic nucleotide phophodiesterases (CaM-PDEs) hydrolyze both cAMP and cGMP and are stimulated 5–15 fold by the binding of calcium and calmodulin (CaM)1,2. These isozymes provide a mechanism whereby calcium, acting as a sec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96d3a3c4f4f3f477cbfc6f702e115ae7
https://doi.org/10.1007/978-1-4684-5679-0_42
https://doi.org/10.1007/978-1-4684-5679-0_42
Publisher Summary This chapter describes the structure and the function of calmodulin-dependent phosphodiesterase isozymes. A cyclic nucleotide phosphodiesterase (PDE) isozyme was the first calmodulin (CaM) target protein discovered and as such was a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c4011a6a3976543e65edf1ec90af724
https://doi.org/10.1016/b978-0-12-521040-9.50092-9
https://doi.org/10.1016/b978-0-12-521040-9.50092-9