Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jeffrey P. Bombardier"'
Autor:
Jennifer H Campbell, Tricia H Burdo, Patrick Autissier, Jeffrey P Bombardier, Susan V Westmoreland, Caroline Soulas, R Gilberto González, Eva-Maria Ratai, Kenneth C Williams
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18688 (2011)
Minocycline is a tetracycline antibiotic that has been proposed as a potential conjunctive therapy for HIV-1 associated cognitive disorders. Precise mechanism(s) of minocycline's functions are not well defined.Fourteen rhesus macaques were SIV infect
Externí odkaz:
https://doaj.org/article/75f63d37f1464e6fbe2341e059c7eebd
Autor:
Eva-Maria Ratai, Jeffrey P Bombardier, Chan-Gyu Joo, Lakshmanan Annamalai, Tricia H Burdo, Jennifer Campbell, Robert Fell, Reza Hakimelahi, Julian He, Patrick Autissier, Margaret R Lentz, Elkan F Halpern, Eliezer Masliah, Kenneth C Williams, Susan V Westmoreland, R Gilberto González
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10523 (2010)
Despite the advent of highly active anti-retroviral therapy (HAART), HIV-associated neurocognitive disorders continue to be a significant problem. In efforts to understand and alleviate neurocognitive deficits associated with HIV, we used an accelera
Externí odkaz:
https://doaj.org/article/430b6637f5a643958106d70d1770da7f
Autor:
Mary Munson, Jeffrey P Bombardier
Publikováno v:
Current Opinion in Chemical Biology. 29:66-71
Membrane fusion is a tightly controlled process in all eukaryotic cell types. The SNARE family of proteins is required for fusion throughout the exocytic and endocytic trafficking pathways. SNAREs on a transport vesicle interact with the cognate SNAR
Autor:
Jeffrey P. Bombardier, Richa Jaiswal, Christopher J. Gould, Bruce L. Goode, Jeff Gelles, Dennis Breitsprecher
Publikováno v:
Science. 336:1164-1168
See How They Grow Controlled assembly and disassembly of the actin cytoskeleton is essential for processes such as cell motility, cytokinesis, and tumor metastasis. The formation of new actin filaments appears to involve the protein formin paired wit
Autor:
Eliezer Masliah, Sarah Pilkenton, Elizabeth Curran, Shawn P. O'Neil, R. Gilberto Gonzalez, Tricia H. Burdo, Woong-Ki Kim, Lakshmanan Annamalai, Patrick Autissier, Kenneth C. Williams, Susan V. Westmoreland, Julian He, Eva-Maria Ratai, Chan-Gyu Joo, Margaret R. Lentz, Robert Fell, Jeffrey P. Bombardier
Publikováno v:
Journal of Medical Primatology. 40:300-309
Background Simian immunodeficiency virus (SIV) infection and persistent CD8+ lymphocyte depletion rapidly leads to encephalitis and neuronal injury. The objective of this study is to confirm that CD8-depletion alone does not affect brain pathology in
Autor:
Robert Fell, Susan V. Westmoreland, Lakshmanan Annamalai, Tricia H. Burdo, Chan-Gyu Joo, Margaret R. Lentz, R. Gilberto Gonzalez, Julian He, Elizabeth Curran, Jeffrey P. Bombardier, Eliezer Masliah, Jennifer H. Campbell, Elkan F. Halpern, Kenneth C. Williams, Eva-Maria Ratai, Reza Hakimelahi
Publikováno v:
Magnetic Resonance in Medicine. 66:625-634
Proton magnetic resonance spectroscopy has emerged as one of the most informative neuroimaging modalities for studying the effect of HIV infection in the brain, providing surrogate markers by which to assess disease progression and monitor treatment.
Autor:
Beena Krishnan, Jiang Hong, Zoya Ignatova, Jeffrey P. Bombardier, Lila M. Gierasch, Anna Marie C. Marcelino
Publikováno v:
Biopolymers. 88:157-163
A crucial challenge in present biomedical research is the elucidation of how fundamental processes like protein folding and aggregation occur in the complex environment of the cell. Many new physico-chemical factors like crowding and confinement must
Autor:
Jeffrey P. Bombardier, Jeff Gelles, Ivan R. Corrêa, Bruce L. Goode, Ming-Qun Xu, Richa Jaiswal, Julian A. Eskin
Publikováno v:
Nature Communications
Precise control of actin filament length is essential to many cellular processes. Formins processively elongate filaments, whereas capping protein (CP) binds to barbed ends and arrests polymerization. While genetic and biochemical evidence has indica
Autor:
R. Gilberto Gonzalez, Tricia H. Burdo, Jeffrey P. Bombardier, Kenneth C. Williams, Patrick Autissier, Eva-Maria Ratai, Susan V. Westmoreland, Jennifer H. Campbell, Caroline Soulas
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 4, p e18688 (2011)
PLoS ONE, Vol 6, Iss 4, p e18688 (2011)
Background Minocycline is a tetracycline antibiotic that has been proposed as a potential conjunctive therapy for HIV-1 associated cognitive disorders. Precise mechanism(s) of minocycline's functions are not well defined. Methods Fourteen rhesus maca
Autor:
Eva-Maria, Ratai, Lakshmanan, Annamalai, Tricia, Burdo, Chan-Gyu, Joo, Jeffrey P, Bombardier, Robert, Fell, Reza, Hakimelahi, Julian, He, Margaret R, Lentz, Jennifer, Campbell, Elizabeth, Curran, Elkan F, Halpern, Eliezer, Masliah, Susan V, Westmoreland, Kenneth C, Williams, R Gilberto, González
Publikováno v:
Magnetic resonance in medicine. 66(3)
Proton magnetic resonance spectroscopy has emerged as one of the most informative neuroimaging modalities for studying the effect of HIV infection in the brain, providing surrogate markers by which to assess disease progression and monitor treatment.