Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Jeffrey P Gavornik"'
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0282349 (2023)
Sex hormones can affect cellular physiology and modulate synaptic plasticity, but it is not always clear whether or how sex-dependent differences identified in vitro express themselves as functional dimorphisms in the brain. Historically, most experi
Externí odkaz:
https://doaj.org/article/df102e1ee7e84a3da61640d7ad996fdb
Autor:
Eitan S Kaplan, Sam F Cooke, Robert W Komorowski, Alexander A Chubykin, Aurore Thomazeau, Lena A Khibnik, Jeffrey P Gavornik, Mark F Bear
Publikováno v:
eLife, Vol 5 (2016)
The roles played by cortical inhibitory neurons in experience-dependent plasticity are not well understood. Here we evaluate the participation of parvalbumin-expressing (PV+) GABAergic neurons in two forms of experience-dependent modification of prim
Externí odkaz:
https://doaj.org/article/d5644dbadef34ef7abebf51f46762011
Publikováno v:
Frontiers in Human Neuroscience, Vol 8 (2014)
The Scalar Timing Law, which is a temporal domain generalization of the well known Weber Law, states that the errors in estimating temporal intervals scale linearly with the durations of the intervals. Linear scaling has been studied extensively in h
Externí odkaz:
https://doaj.org/article/554ae82ff4714195b1ae4ec05c450d10
Autor:
Byron H. Price, Jeffrey P. Gavornik
Publikováno v:
Frontiers in Computational Neuroscience, Vol 16 (2022)
While it is universally accepted that the brain makes predictions, there is little agreement about how this is accomplished and under which conditions. Accurate prediction requires neural circuits to learn and store spatiotemporal patterns observed i
Externí odkaz:
https://doaj.org/article/d2237a6c9eb34584a1aef48d138cd161
Acetylcholine (ACh) is a neurotransmitter that plays a variety of roles in the central nervous system (CNS). It was previously shown that blocking muscarinic receptors with a non-selective antagonist prevents a form of experience-dependent plasticity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c51bd2c030a14f139d33f13e3fe6a4a
https://doi.org/10.1101/2022.02.09.479792
https://doi.org/10.1101/2022.02.09.479792
Repeated exposure to visual sequences changes the form of evoked activity in the primary visual cortex (V1). Predictive coding theory provides a potential explanation for this, namely that plasticity shapes cortical circuits to encode spatiotemporal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba390d59c5ea7c2a505230331e57669f
https://doi.org/10.1101/2021.12.31.474652
https://doi.org/10.1101/2021.12.31.474652
Autor:
Yong-Jun Liu, Hai Zhang, Lujia Chen, Todd C. Holmes, Xiangmin Xu, Jeffrey P. Gavornik, Cary Lai, Sunil P. Gandhi, Steven F. Grieco, Xin Qiao, Xiaoting Zheng
SummarySubanesthetic ketamine evokes rapid and long-lasting antidepressant effects in human patients. The mechanism for ketamine’s effects remains elusive, but ketamine may broadly modulate brain plasticity processes. We show that single-dose ketam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d8b28f74aa55b2391fa4c2ef5d08ca0
https://doi.org/10.1101/2020.03.16.994475
https://doi.org/10.1101/2020.03.16.994475
Autor:
Zhaoxia Yu, Lujia Chen, Jeffrey P. Gavornik, Cary Lai, Todd C. Holmes, Steven F. Grieco, Xiaoting Zheng, Sunil P. Gandhi, Xiangmin Xu, Xin Qiao, Yong-Jun Liu, Hai Zhang
Publikováno v:
Curr Biol
Summary Subanesthetic ketamine evokes rapid and long-lasting antidepressant effects in human patients. The mechanism for ketamine’s effects remains elusive, but ketamine may broadly modulate brain plasticity processes. We show that single-dose keta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffd9b7928f1cd3cefb2b28b2b8ee2e60
https://doi.org/10.1016/j.cub.2020.07.008
https://doi.org/10.1016/j.cub.2020.07.008
Autor:
Jennifer J. Siegel, Michael S. Sidorov, Jeffrey P. Gavornik, Brittany Williams, Benjamin D. Philpot, Hyojin Kim, Marie Rougie
Publikováno v:
Cell reports
SUMMARY Mechanisms of experience-dependent plasticity have been well characterized in mouse primary visual cortex (V1), including a form of potentiation driven by repeated presentations of a familiar visual sequence (“sequence plasticity”). The p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1d3ba3be054e07fe88928bd8705aa28
https://doi.org/10.1016/j.celrep.2020.108152
https://doi.org/10.1016/j.celrep.2020.108152
Publikováno v:
Nature neuroscience
Nat Neurosci
Cooke, S F, Komorowski, R W, Kaplan, E S, Gavornik, J P & Bear, M F 2015, ' Visual Recognition Memory, Manifested as Long-Term Habituation, Requires Synaptic Plasticity in V1 ', Nature Neuroscience, vol. 18, pp. 262-271 . https://doi.org/10.1038/nn.3920
Nat Neurosci
Cooke, S F, Komorowski, R W, Kaplan, E S, Gavornik, J P & Bear, M F 2015, ' Visual Recognition Memory, Manifested as Long-Term Habituation, Requires Synaptic Plasticity in V1 ', Nature Neuroscience, vol. 18, pp. 262-271 . https://doi.org/10.1038/nn.3920
Familiarity with stimuli that bring neither reward nor punishment, manifested through behavioral habituation, enables organisms to detect novelty and devote cognition to important elements of the environment. Here we describe in mice a form of long-t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::772a6c09cd9761a008487a1f318cbf53
http://europepmc.org/articles/PMC4383092
http://europepmc.org/articles/PMC4383092