Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Jeffrey P, Leal"'
Autor:
Kevin H. Leung, Steven P. Rowe, Jeffrey P. Leal, Saeed Ashrafinia, Mohammad S. Sadaghiani, Hyun Woo Chung, Pejman Dalaie, Rima Tulbah, Yafu Yin, Ryan VanDenBerg, Rudolf A. Werner, Kenneth J. Pienta, Michael A. Gorin, Yong Du, Martin G. Pomper
Publikováno v:
EJNMMI Research, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Background Accurate classification of sites of interest on prostate-specific membrane antigen (PSMA) positron emission tomography (PET) images is an important diagnostic requirement for the differentiation of prostate cancer (PCa) from foci
Externí odkaz:
https://doaj.org/article/b41941de8d2b40b8a18526ea80bd1b9d
Autor:
Jeffrey P. Leal, Steven P. Rowe, Vered Stearns, Roisin M. Connolly, Christos Vaklavas, Minetta C. Liu, Anna Maria Storniolo, Richard L. Wahl, Martin G. Pomper, Lilja B. Solnes
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Applications based on artificial intelligence (AI) and deep learning (DL) are rapidly being developed to assist in the detection and characterization of lesions on medical images. In this study, we developed and examined an image-processing workflow
Externí odkaz:
https://doaj.org/article/6602353622f148f4af0f80f202dac714
Autor:
Joo Hyun O, Su Jin Lim, Hao Wang, Jeffrey P. Leal, Hui-Kuo G. Shu, Richard L. Wahl, QIN PET Readers
Publikováno v:
EJNMMI Research, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Background The aim of this study was to assess the reader variability in quantitatively assessing pre- and post-treatment 2-deoxy-2-[18F]fluoro-d-glucose positron emission tomography/computed tomography ([18F]FDG PET/CT) scans in a defined s
Externí odkaz:
https://doaj.org/article/2d11e8204102487291b7ef0e3aaed0f2
Autor:
Steven P. Rowe, Martin G. Pomper, Jeffrey P. Leal, Robert Schneider, Sebastian Krüger, Linda C. Chu, Elliot K. Fishman
Publikováno v:
Abdominal Radiology. 47:3916-3920
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0212573 (2019)
BackgroundPulmonary hypertension (PH) is a known complication of HCM and is a strong predictor of mortality. We aim to investigate the relationship between microvascular dysfunction measured by quantitative PET and PH in HCM patients.MethodsEighty-ni
Externí odkaz:
https://doaj.org/article/748ae57cbe0a471ab62949c97af7425f
Autor:
Manish D. Paranjpe, Xueqi Chen, Min Liu, Ishan Paranjpe, Jeffrey P. Leal, Rongfu Wang, Martin G. Pomper, Dean F. Wong, Tammie L.S. Benzinger, Yun Zhou
Publikováno v:
NeuroImage: Clinical, Vol 22, Iss , Pp - (2019)
While the ApoE ε4 allele is a known risk factor for mild cognitive impairment (MCI) and Alzheimer's disease, brain region specific effects remain elusive. In this study, we investigate whether the ApoE ε4 allele exhibits brain region specific effec
Externí odkaz:
https://doaj.org/article/445b81bf5b1e4163aea249c6a0ce4c4d
Autor:
Wajahat Khatri, Hyun Woo Chung, Rudolf A. Werner, Jeffrey P. Leal, Kenneth J. Pienta, Martin A. Lodge, Michael A. Gorin, Martin G. Pomper, Steven P. Rowe
Publikováno v:
Diagnostics, Vol 11, Iss 4, p 665 (2021)
Purpose: Prostate-specific membrane antigen (PSMA) positron emission tomography (PET) is emerging as an important modality for imaging patients with prostate cancer (PCa). As with any imaging modality, indeterminate findings will arise. The PSMA repo
Externí odkaz:
https://doaj.org/article/3818064d15f54a54a0eb6d53e234179a
Autor:
Elizabeth M. Jaffee, Meizheng Liu, Jonathan D. Powell, Ana De Jesus-Acosta, Dung T. Le, Yafu Yin, Jennifer N. Durham, Elizabeth A. Thompson, Daniel A. Laheru, Annie A. Wu, Amber Vrana, Erkut Borazanci, Katherine M. Bever, Kimberly Pinero, Jeffrey P. Leal, Hao Wang, Lei Zheng, Cara Wilt, Gayle S. Jameson, Wei Fu, Daniel D. Von Hoff
Publikováno v:
Oncotarget
Purpose Metformin combined with the mTOR inhibitor rapamycin showed potential synergistic anti-tumor activity in preclinical studies in pancreatic ductal adenocarcinoma (PDA). This phase 1b study (NCT02048384) was conducted to evaluate the feasibilit
Autor:
Takahiro Higuchi, Alvaro A. Ordonez, Donika Plyku, Camilo A. Ruiz-Bedoya, Rudolf A. Werner, Sanjay K. Jain, Robert F. Dannals, Wojciech G. Lesniak, Daniel P. Holt, Jeffrey P. Leal, Mariah H. Klunk, Steven P. Rowe
Publikováno v:
J Nucl Med
para-Aminobenzoic acid (PABA) has been previously used as an exogenous marker to verify completion of 24-h urine sampling. Therefore, we hypothesized that PABA radiolabeled with (11)C might allow high-quality dynamic PET of the kidneys with less radi
Autor:
Steve Y. Cho, Debra L. Friedman, Lu Chen, Jeffrey P. Leal, Jongho Kim, Allen Buxton, Suzanne L. Wolden, Sarah A. Milgrom, Cindy L. Schwartz, Kathleen M. McCarten, Alin Chirindel, Bradford S. Hoppe, Qinglin Pei, Jihyun Kim, Sandy Kessel, Kara M. Kelly
Publikováno v:
Pediatr Blood Cancer
BACKGROUND Positron emission tomography (PET)-based measures of baseline total-body tumor burden may improve risk stratification in intermediate-risk Hodgkin lymphoma (HL). MATERIALS AND METHODS Evaluable patients were identified from a cohort treate