Zobrazeno 1 - 10
of 229
pro vyhledávání: '"Jeffrey O. Hollinger"'
Autor:
Arun R. Shrivats, Yuji Mishina, Saadyah Averick, Krzysztof Matyjaszewski, Jeffrey O. Hollinger
Publikováno v:
Bioengineering, Vol 2, Iss 3, Pp 160-175 (2015)
RNA interference (RNAi) is a powerful tool to treat diseases and elucidate target gene function. Prior to clinical implementation, however, challenges including the safe, efficient and targeted delivery of siRNA must be addressed. Here, we report cat
Externí odkaz:
https://doaj.org/article/33473c00b6db46c89e6ecd5d54e3cb66
Autor:
Jeffrey O. Hollinger, Bin Hu, Shuang S. Chen, Alexandra K. Pastino, Xiaohuan Wu, Timothy G. Bromage, Ophir Ortiz, Joachim Kohn
Publikováno v:
Regenerative Engineering and Translational Medicine. 6:189-200
Abstract In the present study, a series of four different scaffolds were comparatively evaluated in a goat calvarial critical size defect model. Such studies are only rarely reported in the literature. In our work, E1001(1k), a member of a large comb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d50d86e5f0fae3da9d8fb4f04c59f1c
https://doi.org/10.1007/s40883-019-00144-z
https://doi.org/10.1007/s40883-019-00144-z
Autor:
Conan S. Young, Gino Bradica, Charlie E. Hart, Anuradha Karunanidhi, Reva M. Street, Lyndsey Schutte, Jeffrey O. Hollinger
Publikováno v:
Journal of Tissue Engineering, Vol 1, Iss 1 (2010)
Human platelet-derived growth factor-BB (hPDGF-BB) is a basic polypeptide growth factor released from platelets at the injury site. It is a multifunctional molecule that regulates DNA synthesis and cell division and induces biological effects that
Externí odkaz:
https://doaj.org/article/30daa1f1ac7f417f9c2f13a428efdc66
Autor:
Arpan Satsangi, Chun-Sik Bae, Kyu-Bok Lee, David D Dean, Nicholas Gerken, Mark R. Appleford, Jeffrey O. Hollinger, Joo L. Ong, Joseph J. Pearson, Teja Guda, Sean McBride
Publikováno v:
Journal of biomedical materials research. Part B, Applied biomaterialsREFERENCES. 108(3)
Critically sized bone defects are often compounded by infectious complications. The standard of care consists of bone autografts with systemic antibiotics. These injuries and treatments lead to donor site morbidity, antibiotic resistant strains of ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7f4e17593c2d4740db237e90b935f4f
https://pubmed.ncbi.nlm.nih.gov/31410993
https://pubmed.ncbi.nlm.nih.gov/31410993
Autor:
Krzysztof Matyjaszewski, Saadyah Averick, Jeffrey O. Hollinger, Arun R. Shrivats, Yuji Mishina, Haichun Pan, Molly Klimak, Michael C. McDermott
Publikováno v:
ACS Biomaterials Science & Engineering. 1:1139-1150
Trauma-induced heterotopic ossification (HO) and fibrodysplasia ossificans progressiva (FOP) are acquired and genetic variants of pathological bone formation occurring in soft tissues. Conventional treatment modalities target the inflammatory process
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24a3b981efe6413405159d7babadb01b
https://doi.org/10.1021/acsbiomaterials.5b00294
https://doi.org/10.1021/acsbiomaterials.5b00294
Autor:
Yuji Mishina, Arun R. Shrivats, Jeffrey O. Hollinger, Saadyah Averick, Krzysztof Matyjaszewski
Publikováno v:
Bioengineering
Bioengineering, Vol 2, Iss 3, Pp 160-175 (2015)
Volume 2
Issue 3
Pages 160-175
Bioengineering, Vol 2, Iss 3, Pp 160-175 (2015)
Volume 2
Issue 3
Pages 160-175
RNA interference (RNAi) is a powerful tool to treat diseases and elucidate target gene function. Prior to clinical implementation, however, challenges including the safe, efficient and targeted delivery of siRNA must be addressed. Here, we report cat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb850aacde22935384b23ff8e10c6630
http://europepmc.org/articles/PMC4894740
http://europepmc.org/articles/PMC4894740
Autor:
Saadyah Averick, Jeffrey O. Hollinger, Molly Klimak, Marlene DeMaio, Krzysztof Matyjaszewski, Eric Hsu, Arun R. Shrivats, April C. S. Watt
Publikováno v:
Clinical Orthopaedics & Related Research. 473:2139-2149
Heterotopic ossification (HO) may occur after musculoskeletal trauma, traumatic brain injury, and total joint arthroplasty. As such, HO is a compelling clinical concern in both military and civilian medicine. A possible etiology of HO involves dysreg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5125c871b658e4ea0b654d0530b3650d
https://doi.org/10.1007/s11999-014-4073-0
https://doi.org/10.1007/s11999-014-4073-0
Autor:
Sean McBride, Aniq Darr, Joachim Kohn, Jeffrey O. Hollinger, Jinku Kim, Ophir Ortiz, Maria Hanshella R. Magno
Publikováno v:
Regenerative Biomaterials
Next-generation synthetic bone graft therapies will most likely be composed of resorbable polymers in combination with bioactive components. In this article, we continue our exploration of E1001(1k), a tyrosine-derived polycarbonate, as an orthopedic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c813897fced1400426d1036f0a3b6898
https://doi.org/10.1093/rb/rbu019
https://doi.org/10.1093/rb/rbu019
Autor:
Arun R. Shrivats, Krzysztof Matyjaszewski, Matthew C. Mackenzie, Saadyah Averick, Michael C. McDermott, Dominik Konkolewicz, Jeffrey O. Hollinger
Publikováno v:
Biomacromolecules. 16:236-245
The field of RNA interference depends on the development of safe and efficient carriers for short interfering ribonucleic acid (siRNA) delivery. Conventional cationic monomers for siRNA delivery have utilized the nitrogen heteroatom to produce cation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54983938f36474477c4bab6d1009dcf4
https://doi.org/10.1021/bm501449a
https://doi.org/10.1021/bm501449a
Publikováno v:
Drug Discovery Today. 19:781-786
The quest to surpass the clinical efficacy of the allogeneic bone graft has had limited success, an outcome that is symbolic of tissue engineering as a whole. In this 'State of the Union'-type review, we highlight recent advances in the design of bon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::700457c9d24244b47bdb81847c1e74fd
https://doi.org/10.1016/j.drudis.2014.04.010
https://doi.org/10.1016/j.drudis.2014.04.010