Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jeffrey Nye"'
Autor:
Laura Sudkamp, Matthew Gamette, Ray Wickenheiser, Brooke Arnone, Erin Forry, Linda Jackson, Rita C. Dyas, Lisa Burdett, Bruce Houlihan, Jennifer McNair, Jeffrey Nye, Scott O’Neill, Timothy Scanlan, Tony Tessarolo, Christian Westring, John Byrd, Ramona Robertson
Publikováno v:
Forensic Science International: Synergy, Vol 2, Iss , Pp 349-350 (2020)
Externí odkaz:
https://doaj.org/article/0ce2804465dd43fba21c9422fa2173d7
Autor:
Cong Bi, James Chadwick, Merrill L. Davies, Albert J. DelMonte, Peng Geng, Andrew W. Glace, Rebecca A. Green, John A. Gurak, Matthew W. Haley, Brian L. He, Bahar Inankur, Christopher R. Jamison, Candice L. Joe, Sergei Kolotuchin, Dong Lin, Sha Lou, Jeffrey Nye, Adrian Ortiz, Geoffrey E. Purdum, Victor W. Rosso, Mansi Shah, Eric M. Simmons, Jason M. Stevens, Neil A. Strotman, Yichen Tan, Ling Zhang
Publikováno v:
The Journal of organic chemistry.
The development of a convergent route to the NLRP3 (nucleotide-binding domain and leucine-rich repeat-containing protein 3) agonist BMS-986299 is reported. The synthesis relies on a key Miyaura borylation and a tandem Suzuki-Miyaura coupling between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f146eddbd33628f75341b1e8fea485f
https://pubmed.ncbi.nlm.nih.gov/36516991
https://pubmed.ncbi.nlm.nih.gov/36516991
Autor:
James Chadwick, Candice L. Joe, Jeffrey Nye, Albert J. DelMonte, Sha Lou, Bahar Inankur, Neil A. Strotman
Publikováno v:
Organic Process Research & Development. 25:434-441
A scalable synthesis of 2-chloro-5-(1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol-5-yl)aniline (1), a key intermediate in the synthesis of an immuno-oncology asset, is described. A Negishi cross-coupling...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f13d45db405b7d6237f0ec7178f1293
https://doi.org/10.1021/acs.oprd.0c00414
https://doi.org/10.1021/acs.oprd.0c00414
Autor:
Ray Wickenheiser, Jeffrey Nye, Bruce Houlihan, Scott O’Neill, Rita C. Dyas, Ramona Robertson, Christian Westring, Ascld Staff, Erin Forry, Lisa Burdett, John Byrd, Matthew Gamette, Jennifer McNair, Laura Sudkamp, Timothy Scanlan, Brooke Arnone, Linda Jackson, Tony Tessarolo
Publikováno v:
Forensic Science International: Synergy
Forensic Science International: Synergy, Vol 2, Iss, Pp 349-350 (2020)
Forensic Science International: Synergy, Vol 2, Iss, Pp 349-350 (2020)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd4ecc2ef83897951987eb08c61c78f6
https://pubmed.ncbi.nlm.nih.gov/33385133
https://pubmed.ncbi.nlm.nih.gov/33385133
Publikováno v:
Chemical Engineering in the Pharmaceutical Industry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9cbba47ee266e375c9f1e51fc3b2b48
https://doi.org/10.1002/9781119600800.ch42
https://doi.org/10.1002/9781119600800.ch42
Autor:
Christopher Carney, Jennifer S. Hammons, Eugene Tan, Beth Ann Marne, Jeffrey Nye, Michael Mann, Angelo Della Manna, Erica L. Romsos, Rosemary S. Turingan, Richard F. Selden, Farida Al Shamali, Peter M. Vallone, Julie L. French, Catherine Hogan
Publikováno v:
Forensic Science International: Genetics. 25:145-156
Since the implementation of forensic DNA typing in labs more than 20 years ago, the analysis procedures and data interpretation have always been conducted in a laboratory by highly trained and qualified scientific personnel. Rapid DNA technology has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93405e06cd29a656f1bf500ce8545bda
Autor:
Adrian Ortiz, Shunmugaraj Sathasivam, Jeffrey Nye, Sivaraj Ramasamy, Susanne Kiau, Shankar Tendulkar, Martin D. Eastgate, Rajappa Vaidyanathan, Michael R. Luzung, Neil A. Strotman, Nachiket Likhite, Ye Zhu
Publikováno v:
Organic Process Research & Development. 20:977-981
The large-scale synthesis of ethyl 4-bromocyclohex-3-enecarboxyalate, using a mild brominating reagent derived from triphenyl phosphite and bromine, is reported. The development and comparison of both continuous and batch processes are described. A m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adffe775c4d989aed2130779445c2189
https://doi.org/10.1021/acs.oprd.6b00100
https://doi.org/10.1021/acs.oprd.6b00100
Autor:
Tamas Benkovics, Maxime Soumeillant, Susanne Kiau, Neil A. Strotman, Adrian Ortiz, Jeffrey Nye, Yichen Tan, Sloan Ayers, Scott A. Savage, Zhongmin Xu, Matthew W. Haley, Qi Gao
Publikováno v:
The Journal of organic chemistry. 82(9)
A concise and scalable second generation synthesis of HIV maturation inhibitor BMS-955176 is described. The synthesis is framed by an oxidation strategy highlighted by a CuI mediated aerobic oxidation of betulin, a highly selective PIFA mediated dehy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::453b164a4da50338544c5d7fecd7a1b0
https://pubmed.ncbi.nlm.nih.gov/28406018
https://pubmed.ncbi.nlm.nih.gov/28406018
Autor:
Carolyn R. Hill, Nicole Frazier, Karen Oyerly, Lesley Katzilierakis, Natasha Williams, Martin G. Ensenberger, Kristy A. Lenz, Amber Sage, Kathryn Oostdik, Clint Buchanan, Learden K. Matthies, Scott Bruski, Donald Yet, Hays Young, Kristin Schelling, Jeanne M. Bourdeau, Katie L. Swango, Benjamin E. Krenke, Jeffrey Nye, Cynthia J. Sprecher, Jody Koehler, Joshua Strong, Regina Wells, Monica Price, Jessica Linner, Jeff Hahn, Joel Sutton, Douglas R. Storts, Melisa Staples, Wendy Duke
Publikováno v:
Forensic Science International: Genetics. 12:69-76
The original CODIS database based on 13 core STR loci has been overwhelmingly successful for matching suspects with evidence. Yet there remain situations that argue for inclusion of more loci and increased discrimination. The PowerPlex® Fusion Syste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf36f2c8adf8f7a16d9a61c605ce8490
Autor:
Tamas Benkovics, David R. Kronenthal, Jeffrey Nye, Gregory L. Beutner, Chris Sfouggatakis, Adrian Ortiz, Michael S. Bultman, Zhongping Shi
Publikováno v:
ChemInform. 46
Title compound (IX*) is prepared from racemic lactol (I) using small-molecule-mediated dynamic kinetic resolution and a selective pyranose-to-furanose ring contraction as the key steps.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a4e0847426642f0475aadbeac4a3d2d
https://doi.org/10.1002/chin.201542135
https://doi.org/10.1002/chin.201542135