Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Jeffrey N. Stirman"'
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Imaging of neuronal activity across distant brain regions is challenging. Here, the authors introduce a two-photon microscope with two independently controlled scan engines, and demonstrate calcium imaging with subcellular resolution in brain regions
Externí odkaz:
https://doaj.org/article/61e2b203f08348f7bc349521ead6e6c7
Autor:
Mitchell Clough, Ichun Anderson Chen, Seong-Wook Park, Allison M. Ahrens, Jeffrey N. Stirman, Spencer L. Smith, Jerry L. Chen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-7 (2021)
Functional brain imaging with two-photon microscopy is limited by a tradeoff between imaging area and acquisition speed. Here, the authors present Quadroscope, a flexible microscope which allows for simultaneous video rate acquisition of four indepen
Externí odkaz:
https://doaj.org/article/b981c71532914106a9b1e5778371edc0
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Nature Communications
Nature communications, vol 12, iss 1
Nature Communications
Nature communications, vol 12, iss 1
Imaging the activity of neurons that are widely distributed across brain regions deep in scattering tissue at high speed remains challenging. Here, we introduce an open-source system with Dual Independent Enhanced Scan Engines for Large field-of-view
Autor:
Seong-Wook Park, Allison M. Ahrens, Ichun Anderson Chen, Mitchell Clough, Jerry L. Chen, Jeffrey N. Stirman, Spencer L. Smith
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-7 (2021)
Nature Communications
Nature Communications
Understanding brain function requires monitoring local and global brain dynamics. Two-photon imaging of the brain across mesoscopic scales has presented trade-offs between imaging area and acquisition speed. We describe a flexible cellular resolution
Publikováno v:
Current Biology. 32:2810-2820.e5
Mice have a constellation of higher visual areas, but their functional specializations are unclear. Here, we used a data-driven approach to examine neuronal representations of complex visual stimuli across mouse higher visual areas, measured using la
Publikováno v:
Conference on Lasers and Electro-Optics.
We developed a large field-of-view (0>5mm) two-photon microscopy with simultaneous and independent two-region access to enable the imaging of neuronal activities widely-distributed in mice’s visual cortex, which is hardly achievable with current co
Publikováno v:
Nature biotechnology, vol 34, iss 8
Nature biotechnology
Nature biotechnology
Two-photon calcium imaging provides an optical readout of neuronal activity in populations of neurons with subcellular resolution. However, conventional two-photon imaging systems are limited in their field of view to ∼1 mm(2), precluding the visua
Publikováno v:
Yu, Y; Hira, R; Stirman, JN; Yu, W; Smith, IT; & Smith, SL. (2018). Mice use robust and common strategies to discriminate natural scenes.. Scientific reports, 8(1), 1379. doi: 10.1038/s41598-017-19108-w. UC Santa Barbara: Retrieved from: http://www.escholarship.org/uc/item/3g11d75m
Scientific reports, vol 8, iss 1
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports
Scientific reports, vol 8, iss 1
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports
Visual perception is essential for animal survival in natural environments. Mice use vision to navigate and avoid predators. However, the spatial resolution of mouse vision is poor compared to primates and carnivores, and mice lack a fovea. Thus, it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aed2e753e1380a92ae053afda9af9df0
Autor:
Jeffrey N. Stirman, Spencer L. Smith
Publikováno v:
Optics in the Life Sciences Congress.
Using custom and adaptive optics, we developed multiphoton calcium imaging systems for large volumes (~ 20 cubic millimeters), with subcellular and subsecond resolution, and independent, temporally multiplexed beams for neuroscience research.
Global motion perception is a function of higher, or extrastriate, visual system circuitry. These circuits can be engaged in visually driven navigation, a behavior at which mice are adept. However, the properties of global motion perception in mice a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f1b8a4c6676d91a324f5d017e690a7a