Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jeffrey McGuire"'
Autor:
Lucille Lumley, Dennis Miller, William T. Muse, Brenda Marrero‐Rosado, Marcio de Araujo Furtado, Michael Stone, Jeffrey McGuire, Christopher Whalley
Publikováno v:
Epilepsia Open, Vol 4, Iss 3, Pp 382-396 (2019)
Abstract Objective Our objective was to evaluate the protective efficacy of the neurosteroid pregnanolone (3α‐hydroxy‐5β pregnan‐20‐one), a GABAA receptor‐positive allosteric modulator, as an adjunct to benzodiazepine therapy against the
Externí odkaz:
https://doaj.org/article/42d2473c8f4c4c4f928e47706e64ac82
Autor:
Maren Böse, Jennifer Andrews, Colin O’Rourke, Deborah Kilb, Angela Lux, Julian Bunn, Jeffrey McGuire
Publikováno v:
Seismological Research Letters. 94:243-259
We test the behavior of the United States (US) West Coast ShakeAlert earthquake early warning (EEW) system during temporally close earthquake pairs to understand current performance and limitations. We consider performance metrics based on source par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::564d27900efbd96285c92db17895822a
https://doi.org/10.1785/0220220088
https://doi.org/10.1785/0220220088
Autor:
Sara K. McBride, Danielle F. Sumy, Andrea L. Llenos, Grace A. Parker, Jeffrey McGuire, Jessie K. Saunders, Men-Andrin Meier, Pascal Schuback, Douglas Given, Robert de Groot
Publikováno v:
Safety Science, 157
ShakeAlert, the earthquake early warning (EEW) system for the West Coast of the United States, attempts to provides crucial warnings before strong shaking occurs. However, because the alerts are triggered only when an earthquake is already in progres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e7e54251a0ba26b81d0553223610153
Publikováno v:
Advanced Drug Delivery Reviews. 55:217-250
The current review presents an update of drug delivery using poly(ethylene glycol) (PEG), that focuses on recent developments in both protein and organic drugs. Certainly the past 10 years has resulted in a renaissance of the field of PEG drug conjug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3356a6984ea905f699ab468c5794378
https://doi.org/10.1016/s0169-409x(02)00180-1
https://doi.org/10.1016/s0169-409x(02)00180-1
Autor:
Leonel Ochoa, Garry Schwartz, Bahram Forouzesh, Lisa A. Hammond, Amita Patnaik, Chris H. Takimoto, Jinee Rizzo, Andrew Goetz, Anthony W. Tolcher, Joseph Kwiatek, Louis Denis, Jeffrey McGuire, Eric K. Rowinsky
Publikováno v:
Journal of Clinical Oncology. 21:148-157
Purpose: To assess the feasibility of administering camptothecin (CPT), the prototypic topoisomerase I inhibitor, as polyethylene glycol (PEG)-CPT, a macromolecule consisting of CPT conjugated to chemically modified PEG. The study also sought to dete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6e0eae6edc188897108747007531d91
https://doi.org/10.1200/jco.2003.03.143
https://doi.org/10.1200/jco.2003.03.143
Publikováno v:
Bioconjugate Chemistry. 12:163-169
Using lysozyme as a representative protein substrate that loses its activity when PEGylation takes place on the epsilon-amino group of lysine residues, various amounts of a novel releasable PEG linker (rPEG) were conjugated to the protein. rPEG-lysoz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a5b3fa02524c32d22c854236020c2fa
https://doi.org/10.1021/bc000064z
https://doi.org/10.1021/bc000064z
Autor:
David Filpula, Jeffrey McGuire
Publikováno v:
Expert Opinion on Therapeutic Patents. 9:231-245
One decade after the invention of single-chain Fv (sFv) proteins and methods for their facile engineering in microbial systems, there have been several recent engineering advances which combine the avidity, effector and pharmacological properties of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc0ec6964f90bf980da2439d9570e008
https://doi.org/10.1517/13543776.9.3.231
https://doi.org/10.1517/13543776.9.3.231