Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Jeffrey Marine"'
Autor:
Jennifer R. Brown, Wael A. Harb, Brian T. Hill, Janice Gabrilove, Jeff P. Sharman, Marshall T. Schreeder, Paul M. Barr, James M. Foran, Thomas P. Miller, Jan A. Burger, Kevin R. Kelly, Daruka Mahadevan, Shuo Ma, Yan Li, Daniel W. Pierce, Evelyn Barnett, Jeffrey Marine, Monika Miranda, Ada Azaryan, Xujie Yu, Pilar Nava-Parada, Jay Mei, Thomas J. Kipps
Publikováno v:
Haematologica, Vol 101, Iss 7 (2016)
Externí odkaz:
https://doaj.org/article/db5807b237c04ee6a0ab7b5f4796f605
Autor:
Shuo Ma, James M. Foran, Thomas J. Kipps, Yan Li, Xujie Yu, Jeffrey Marine, Jeff P. Sharman, Jan A. Burger, Marshall T. Schreeder, Wael A. Harb, Paul M. Barr, Janice Gabrilove, Kevin R. Kelly, Jay Mei, Daruka Mahadevan, Thomas P. Miller, Evelyn Barnett, Pilar Nava-Parada, Daniel W. Pierce, Jennifer R. Brown, Monika Miranda, Ada Azaryan, Brian T. Hill
B-cell receptor (BCR) signaling plays a key role in the pathogenesis of B-cell malignancies, mediating the survival and proliferation of malignant B cells.1,2 Clinical studies have shown that Bruton’s tyrosine kinase (BTK) inhibitors are well toler
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88ca8de2602ad6cd9e51720ed9c9c385
https://europepmc.org/articles/PMC5004476/
https://europepmc.org/articles/PMC5004476/
Autor:
Jay Mei, Jeffrey Marine, Carla Heise, Evelyn Barnett, Daniel W. Pierce, Sharon Aslanian, Rajesh Chopra, Marianna Zavodovskaya, Varsha Gandhi, Sabine Ponader, Susan O'Brien, Juswinder Singh, Jan A. Burger, Pilar Nava-Parada, M. Nacht, Sean Hong, William G. Wierda, Shijuan Wu, Kumudha Balakrishnan, Xiping Liu
Publikováno v:
Blood. 122:4169-4169
Introduction The B-cell receptor (BCR) and its downstream effectors have emerged as important therapeutic targets in B-cell malignancies. CC-292 is a novel, potent, covalent, and highly selective inhibitor of Btk (IC50apparent of 0.5 nM, kinact/KI ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35c96353896a88a81b4bbad20db31dd5
https://doi.org/10.1182/blood.v122.21.4169.4169
https://doi.org/10.1182/blood.v122.21.4169.4169
Autor:
Brian T. Hill, Thomas P. Miller, Pilar Nava-Parada, Janice Gabrilove, Daruka Mahadevan, Wael A. Harb, Jeffrey Marine, Marshall T. Schreeder, Jan A. Burger, Paul M. Barr, Shuo Ma, Jay Mei, Ada Azaryan, James M. Foran, Thomas J. Kipps, Evelyn Barnett, Kevin R. Kelly, Jennifer R. Brown, Jeff P. Sharman
Publikováno v:
Blood. 122:1630-1630
Introduction CC-292, an oral, highly selective, small-molecule irreversible-inhibitor of Btk is under investigation for the treatment of CLL and other B-cell malignancies. This phase 1 trial investigated the safety, dose limiting toxicities (DLT), an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::470f7b0f3ffe7f2c1317b408a777a0e0
https://doi.org/10.1182/blood.v122.21.1630.1630
https://doi.org/10.1182/blood.v122.21.1630.1630
Publikováno v:
Historical Records of Australian Science; Jun2016, Vol. 27 Issue 1, p81-91, 14p
Autor:
Moss, Victoria
Publikováno v:
Marie Claire (UK Edition); May2019, p74-76, 3p, 3 Color Photographs
Publikováno v:
Inflammation Research; Sep2004 Supplement, Vol. 53, pS207-S230, 24p
Autor:
Ulanski, Stan L.
Coursing through the Atlantic Ocean is a powerful current with a force 300 times that of the mighty Amazon. Ulanski explores the fascinating science and history of this sea highway known as the Gulf Stream, a watery wilderness that stretches from the
Autor:
Gale Research Inc
This respected resource is a biographical dictionary of the significant players in the physical, biological and related sciences. Each edition includes biographical entries on nearly 135,000 living scientists, providing birthdate; birthplace; field o