Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jeffrey Maniko"'
Autor:
Vincent Libis, Niv Antonovsky, Mengyin Zhang, Zhuo Shang, Daniel Montiel, Jeffrey Maniko, Melinda A. Ternei, Paula Y. Calle, Christophe Lemetre, Jeremy G. Owen, Sean F. Brady
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Soil microorganisms are a rich source of bioactive molecules. Here, the authors present a targeted sequencing workflow that reconstructs the clustered organization of biosynthetic domains in metagenomic libraries from amplicon data, thus guiding the
Externí odkaz:
https://doaj.org/article/2be2b1b1e1544062afa735e20fcd1c7b
Autor:
Niv Antonovsky, Sean F. Brady, Mengyin Zhang, Zhuo Shang, Jeremy G. Owen, Paula Y. Calle, Jeffrey Maniko, Vincent Libis, Melinda A. Ternei, Daniel Montiel, Christophe Lemetre
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Nature Communications
Nature Communications
Sequencing of DNA extracted from environmental samples can provide key insights into the biosynthetic potential of uncultured bacteria. However, the high complexity of soil metagenomes, which can contain thousands of bacterial species per gram of soi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ae1feb5a5467c62493956c17b86ccfe
https://doaj.org/article/2be2b1b1e1544062afa735e20fcd1c7b
https://doaj.org/article/2be2b1b1e1544062afa735e20fcd1c7b
Autor:
Jeffrey Maniko, Shishir K. Maithel, Jessica M Keilson, Jennifer Holder-Murray, Glen C. Balch, Jason T. Wiseman, Saif Hamdan, Philip S. Bauer, Lillias H. Maguire, Adriana C. Gamboa, Katherine Hrebinko, Matthew L. Silviera, Sherif Abdel-Misih, Alexander T. Hawkins, Michael K. Turgeon
Publikováno v:
J Surg Oncol
INTRODUCTION: Management of retroperitoneal and lateral pelvic lymph nodes (RLPN) in rectal cancer remains unclear. With total neoadjuvant therapy (TNT), more patients have radiologic complete clinical response (rCR). We sought to evaluate the impact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfedd52d288b0dfaf1fc0667535a3455
https://europepmc.org/articles/PMC8433488/
https://europepmc.org/articles/PMC8433488/
Autor:
Sarah Charlop-Powers, Sean F. Brady, Jeanne Garbarino, Paula Y. Calle, Bradley M. Hover, Helen M. Forgione, Krista L. McGuire, Clara C. Pregitzer, Zachary Charlop-Powers, Jeffrey Maniko, Christophe Lemetre, Melinda A. Ternei
Publikováno v:
Proceedings of the National Academy of Sciences. 113:14811-14816
Numerous therapeutically relevant small molecules have been identified from the screening of natural products (NPs) produced by environmental bacteria. These discovery efforts have principally focused on culturing bacteria from natural environments r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e8985a4543f457dbf55925f24a2698d
https://doi.org/10.1073/pnas.1615581113
https://doi.org/10.1073/pnas.1615581113
Autor:
Alexander T. Hawkins, Adriana C. Gamboa, Glen C. Balch, Kamren Edwards-Hollingsworth, Jennifer Holder-Murray, Sherif Abdel-Misih, Rachel M. Lee, Maryam K. Mohammed, Jason T. Wiseman, Lillias H. Maguire, Jeffrey Maniko, Philip S. Bauer, Charles W. Kimbrough, Shishir K. Maithel, Matthew L. Silviera, Michael K. Turgeon
Publikováno v:
Journal of Clinical Oncology. 38:47-47
47 Background: The optimal level of pedicle ligation during proctectomy for rectal cancer, either at the origin of the inferior mesenteric artery (IMA) or the superior rectal artery (SRA), is still debated. Reasons for IMA ligation include facilitati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bddb1184f15b9c4bb8901e5ab3c36087
https://doi.org/10.1200/jco.2020.38.4_suppl.47
https://doi.org/10.1200/jco.2020.38.4_suppl.47
Autor:
Sean F. Brady, Andrew J. Lowe, Christophe Lemetre, Jeffrey Maniko, Zachary Charlop-Powers, Ben Sparrow
Although bacterial bioactive metabolites have been one of the most prolific sources of lead structures for the development of small-molecule therapeutics, very little is known about the environmental factors associated with changes in secondary metab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04941e82cf5820b7dd15e29bfb861969
https://europepmc.org/articles/PMC5676913/
https://europepmc.org/articles/PMC5676913/
Autor:
Steven Park, Seong-Hwan Kim, Zachary Charlop-Powers, Jeremy G. Owen, Micah Katz, David S. Perlin, Andreia B. Estrela, Sean F. Brady, Melinda A. Ternei, Bradley M. Hover, Henrik Molina, Jeffrey Maniko
Publikováno v:
Nature microbiology. 3(4)
Despite the wide availability of antibiotics, infectious diseases remain a leading cause of death worldwide 1 . In the absence of new therapies, mortality rates due to untreatable infections are predicted to rise more than tenfold by 2050. Natural pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ed4d9f9fa66cdd982ea956beec3ccd7
https://pubmed.ncbi.nlm.nih.gov/29588534
https://pubmed.ncbi.nlm.nih.gov/29588534