Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jeffrey M. Vargason"'
Publikováno v:
Journal of Chemical Education. 90:926-929
In a guided-inquiry laboratory experience, students encounter data that give them the opportunity to discover a concept on their own. Nuclear magnetic resonance (NMR) spectra and inquiry-based pedagogy are used to guide general-chemistry students to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::333b2fb896ddfa0cdf765e7ce450f675
https://doi.org/10.1021/ed300400y
https://doi.org/10.1021/ed300400y
Publikováno v:
Nucleic Acids Research. 32:6501-6510
An analysis of the human chromosome 22 genomic sequence shows that both Z-DNA forming regions (ZDRs) and promoter sites for nuclear factor-I (NFI) are correlated with the locations of known and predicted genes across the chromosome and accumulate aro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4cd8e3dcb1856a1596a545c01b63cf2
https://doi.org/10.1093/nar/gkh988
https://doi.org/10.1093/nar/gkh988
Autor:
P. Shing Ho, Jeffrey M. Vargason
Publikováno v:
Journal of Biological Chemistry. 277:21041-21049
The single crystal structure of the methylated sequence d(CCGGTACm5CGG) has been solved as an antiparallel stacked X Holliday junction to 1.5 A resolution. When compared with the parent nonmethylated d(CCGGTACCGG) structure, the duplexes are translat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89b5dfdfdaf7caa273a91fcb67da8a18
https://doi.org/10.1074/jbc.m201357200
https://doi.org/10.1074/jbc.m201357200
Publikováno v:
Proceedings of the National Academy of Sciences. 98:7265-7270
The transition between B- and A-DNA was first observed nearly 50 years ago. We have now mapped this transformation through a set of single-crystal structures of the sequence d(GGCGCC) 2 , with various intermediates being trapped by methylating or bro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c6b85f2063396836bcbab23dd0de24f
https://doi.org/10.1073/pnas.121176898
https://doi.org/10.1073/pnas.121176898
Publikováno v:
Nature Structural Biology. 7:758-761
Cytosine methylation or bromination of the DNA sequence d(GGCGCC)2 is shown here to induce a novel extended and eccentric double helix, which we call E-DNA. Like B-DNA, E-DNA has a long helical rise and bases perpendicular to the helix axis. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edad5b4e5850621b13f9b6dc1b0bdf5e
https://doi.org/10.1038/78985
https://doi.org/10.1038/78985
Publikováno v:
Methods (San Diego, Calif.). 64(1)
Suppression is a common mechanism employed by viruses to evade the antiviral effects of the host's RNA silencing pathway. The activity of suppression has commonly been localized to gene products in the virus, but the variety of mechanisms used in sup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b656e36ac7448a608a88a3f6893bc677
https://pubmed.ncbi.nlm.nih.gov/23981361
https://pubmed.ncbi.nlm.nih.gov/23981361
Publikováno v:
Biochemistry. 42(32)
Structures of the DNA sequences d(CCGGCGCCGG) and d(CCAGTACbr(5)UGG) are presented here as four-way Holliday junctions in their compact stacked-X forms, with antiparallel alignment of the DNA strands. Thus, the ACC-trinucleotide motif, previously ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84c8597502c228aced0aee984ae79691
https://pubmed.ncbi.nlm.nih.gov/12911300
https://pubmed.ncbi.nlm.nih.gov/12911300
Autor:
Jeffrey M, Vargason, P Shing, Ho
Publikováno v:
The Journal of biological chemistry. 277(23)
The single crystal structure of the methylated sequence d(CCGGTACm(5)CGG) has been solved as an antiparallel stacked X Holliday junction to 1.5 A resolution. When compared with the parent nonmethylated d(CCGGTACCGG) structure, the duplexes are transl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::953f49cd2006720d16c3ce46a2239d4e
https://pubmed.ncbi.nlm.nih.gov/11919197
https://pubmed.ncbi.nlm.nih.gov/11919197
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 97(8)
Holliday junctions are important structural intermediates in recombination, viral integration, and DNA repair. We present here the single-crystal structure of the inverted repeat sequence d(CCGGTACCGG) as a Holliday junction at the nominal resolution
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d820868053fd5ef8aaa89537a02b30
https://pubmed.ncbi.nlm.nih.gov/10760268
https://pubmed.ncbi.nlm.nih.gov/10760268
Autor:
P. Shing Ho, Jeffrey M. Vargason
Publikováno v:
Nature Structural Biology. 8:107-108
We recently published the structure of a DNA double-helix induced by cytosine methylation and bromination, and called this conformation `E-DNA' to recognize the extended rise and eccentric trace of the helix backbone1. It has come to our attention fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9dd68341fd993a97340faea88fa10bd2
https://doi.org/10.1038/84081
https://doi.org/10.1038/84081