Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Jeffrey M. Ostrove"'
Autor:
Jeffrey H. Kordower, Roy A.E. Bakay, Steven G. Potkin, Mary Pay, Tiffany L. Baumann, Michael S. Rafii, David Keator, Jeffrey M. Ostrove, Joao Siffert, David P. Salmon, Yaping Chu, Kathie M. Bishop, Christopher D. Herzog, Raymond T. Bartus, David Barba, Adam S. Fleisher
Publikováno v:
Alzheimer'sdementia : the journal of the Alzheimer's Association. 10(5)
Background Nerve growth factor (NGF) is an endogenous neurotrophic-factor protein with the potential to restore function and to protect degenerating cholinergic neurons in Alzheimer's disease (AD), but safe and effective delivery has proved unsuccess
Publikováno v:
Virology. 192:370-374
A cellular DNA binding protein, which we term Leader Binding Protein-2 (LBP-2), binds near the transcriptional initiation site of the human immunodeficiency virus type 1 (HIV-1) promoter. This protein recognizes a motif similar to that of LBP-1, a pu
Publikováno v:
The Pediatric Infectious Disease Journal. 11:327-330
Autor:
Jeffrey M. Ostrove, Kathie M. Bishop, Jeffrey H. Kordower, Raymond T. Bartus, Mark H. Tuszynski, Christopher D. Herzog, Mehdi Gasmi
Publikováno v:
Parkinsonismrelated disorders. 13
Purpose To develop CERE-120 (AAV-NTN) as a novel therapy for Parkinson's disease (PD) that might restore function of degenerating dopamine neurons and prevent further degeneration. Scope A nonclinical program demonstrated that NTN expression can be p
Autor:
Eugene O. Major, Bagher Forghani, Jose G. Assouline, Myron J. Levin, Jeffrey M. Ostrove, Sharon E. Straus
Publikováno v:
Virology. 179:834-844
Human fetal cell cultures enriched for astrocytes, Schwann cells, or dorsal root ganglia neurons were infected with cell-free varicella-zoster virus (VZV), and the course of these infections was compared with that in fetal fibroblasts. Virus replicat
Autor:
Eric G. Romanowski, Jennifer L. C. McKnight, Jeffrey M. Ostrove, T Araullo-Cruz, Y. Jerold Gordon
Publikováno v:
Virology. 178:469-477
HSV-1 latency and reactivation were studied in vivo by spontaneous and iontophoresis-induced ocular viral shedding in New Zealand rabbits, Balb/c and A/J mice latently infected with wild-type KOS, and dl x 3.1, a progeny ICP0 deletion mutant. The pre
Publikováno v:
New Developments and New Applications in Animal Cell Technology ISBN: 0792350162
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d5c2a1ff73bb0e2935d6e1b18a9ecb0
https://doi.org/10.1007/0-306-46860-3_94
https://doi.org/10.1007/0-306-46860-3_94
Autor:
Flavia Borellini, Jeffrey M. Ostrove
Publikováno v:
Gene Therapy Technologies, Applications and Regulations: From Laboratory to Clinic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a36904c6123be802d3701a61cc259be5
https://doi.org/10.1002/0470842385.ch18
https://doi.org/10.1002/0470842385.ch18
Autor:
Robert L. Martuza, Fred D. Lakeman, Samuel D. Rabkin, Jeffrey M. Ostrove, Erin Mitchell, Tomoki Todo, Daniel Belliveau, Joseph T. Newsome, Frank Feigenbaum, Paul Johnson
Publikováno v:
Daniel J. Belliveau
G207 is a multimutated, conditionally replicating herpes simplex virus type 1 (HSV-1) that is currently in clinical trial for patients with malignant glioma. G207 exhibits an efficient oncolytic activity in tumor cells, yet minimal toxicity in normal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c2c1e9cc7b9d8032ba18bb8ca317bf6
https://works.bepress.com/daniel_belliveau/8
https://works.bepress.com/daniel_belliveau/8
Publikováno v:
Biologicals : journal of the International Association of Biological Standardization. 25(4)
During the manufacture of biopharmaceuticals, numerous adventitious agents have been detected in Master Cell Banks, end-of-production cells as well as bulk harvest fluid. Recently, a number of large-scale production bioreactors have become infected w