Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jeffrey M. Melancon"'
Publikováno v:
Journal of Virology. 78:7329-7343
The herpes simplex virus type 1 UL20 protein (UL20p) is an important determinant for cytoplasmic virion morphogenesis and virus-induced cell fusion. To delineate the functional domains of the UL20 protein, we generated a panel of single and multiple
Publikováno v:
Journal of Virology. 78:5347-5357
The herpes simplex virus type 1 (HSV-1) UL20 protein is an important determinant for virion morphogenesis and virus-induced cell fusion. A precise deletion of the UL20 gene in the HSV-1 KOS strain was constructed without affecting the adjacent UL20.5
Publikováno v:
Pediatric Dermatology. 29:131-133
Publikováno v:
Pediatric dermatology. 29(1)
Publikováno v:
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]. 37(12)
Autor:
Jeffrey M, Melancon, Carter, Davis, Kian, Ehsan, Robyn, Deranger, Frederick R, Helmcke, Fred A, Lopez
Publikováno v:
The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society. 162(5)
Publikováno v:
Virology Journal, Vol 4, Iss 1, p 120 (2007)
Virology Journal
Virology Journal
The HSV-1 UL20 protein (UL20p) and glycoprotein K (gK) are both important determinants of cytoplasmic virion morphogenesis and virus-induced cell fusion. In this manuscript, we examined the effect of UL20 mutations on the coordinate transport and Tra
Autor:
Larry G. Lomax, Anna Israyelyan, Jeffrey M. Melancon, Vladimir N. Chouljenko, Inder Sehgal, Abolghasem Baghian, Carola Leuschner, Konstantin G. Kousoulas, Michael T. Kearney
Publikováno v:
Human gene therapy. 18(5)
A new oncolytic and fusogenic herpes simplex virus type 1 (HSV-1) was constructed on the basis of the wildtype HSV-1(F) strain. To provide for safety and tumor selectivity, the virus carried a large deletion including one of the two alpha4, gamma(1)3
Publikováno v:
Journal of virology. 81(7)
Egress of herpes simplex virus type 1 (HSV-1) from the nucleus of the infected cell to extracellular spaces involves a number of distinct steps, including primary envelopment by budding into the perinuclear space, de-envelopment into the cytoplasm, c
Publikováno v:
Journal of virology. 79(1)
Multiple amino acid changes within herpes simplex virus type 1 (HSV-1) gB and gK cause extensive virus-induced cell fusion and the formation of multinucleated cells (syncytia). Early reports established that syncytial mutations in gK could not cause