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pro vyhledávání: '"Jeffrey M. Grimes"'
Autor:
Michael L. Dixon, Lin Luo, Sadashib Ghosh, Jeffrey M. Grimes, Jonathan D. Leavenworth, Jianmei W. Leavenworth
Publikováno v:
Molecular Cancer, Vol 20, Iss 1, Pp 1-24 (2021)
Abstract Background Accumulation of Foxp3+ regulatory T (Treg) cells in the tumor often represents an important mechanism for cancer immune evasion and a critical barrier to anti-tumor immunity and immunotherapy. Many tumor-infiltrating Treg cells di
Externí odkaz:
https://doaj.org/article/30ce81d646da475cb6af87c87c5a8680
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/cfd2ad1fe47040309a3f1676f6f82c01
Autor:
Jonathan D. Leavenworth, Michael L. Dixon, Sadashib Ghosh, Lin Luo, Jeffrey M. Grimes, Jianmei W. Leavenworth
Publikováno v:
Molecular Cancer, Vol 20, Iss 1, Pp 1-24 (2021)
Background Accumulation of Foxp3+ regulatory T (Treg) cells in the tumor often represents an important mechanism for cancer immune evasion and a critical barrier to anti-tumor immunity and immunotherapy. Many tumor-infiltrating Treg cells display an
Autor:
Natalia Filippova, Jeffrey M Grimes, Jianmei W Leavenworth, David Namkoong, Xiuhua Yang, Peter H King, Michael Crowley, David K Crossman, L Burt Nabors
Publikováno v:
Neuro-Oncology Advances. 4
Background Tumor cellular and molecular heterogeneity is a hallmark of glioblastoma and underlies treatment resistance and recurrence. This manuscript investigated the myeloid-derived microenvironment as a driver of glioblastoma heterogeneity and pro
Autor:
Jeffrey M Grimes, Charles Murchison, James S New, David Crossman, James M Markert, Jianmei Wu Leavenworth
Publikováno v:
The Journal of Immunology. 208:66.13-66.13
Malignant glioma remains a fatal disease with a dismal survival rate. To address this urgent medical need, we pioneered the concept of engineered oncolytic viruses for cancer. Using the herpes simplex virus (HSV)-1 as an experimental virus, our publi