Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Jeffrey M. Grabowski"'
Autor:
Nunya Chotiwan, Carlos A. Brito-Sierra, Gabriella Ramirez, Elena Lian, Jeffrey M. Grabowski, Babara Graham, Catherine A. Hill, Rushika Perera
Publikováno v:
Parasites & Vectors, Vol 15, Iss 1, Pp 1-15 (2022)
Abstract Background Fatty acids are the building blocks of complex lipids essential for living organisms. In mosquitoes, fatty acids are involved in cell membrane production, energy conservation and expenditure, innate immunity, development and repro
Externí odkaz:
https://doaj.org/article/5f4af11955c2405ea9cabd0ed291e763
Autor:
Konstantin A. Tsetsarkin, Olga A. Maximova, Guangping Liu, Heather Kenney, Natalia Teterina, Marshall E. Bloom, Jeffrey M. Grabowski, Luwanika Mlera, Bianca M. Nagata, Ian Moore, Craig Martens, Emerito Amaro-Carambot, Elaine W. Lamirande, Stephen S. Whitehead, Alexander G. Pletnev
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
The mechanisms of ZIKV persistence in the male reproductive tract (MRT) are poorly understood. Here, Tsetsarkin et al. applied microRNA-targeting approach to trace routes of ZIKV dissemination in the testis and epididymis and to generate immunogenic
Externí odkaz:
https://doaj.org/article/ee7bfcbe055342979d1b86ee82672e3a
Autor:
Jeffrey M. Grabowski, Olof R. Nilsson, Elizabeth R. Fischer, Dan Long, Danielle K. Offerdahl, Yoonseong Park, Dana P. Scott, Marshall E. Bloom
Publikováno v:
mBio, Vol 10, Iss 1 (2019)
ABSTRACT The Ixodes scapularis tick transmits a number of pathogens, including tick-borne flaviviruses (TBFVs). In the United States, confirmed human infections with the Powassan virus (POWV) TBFV have a fatality rate of ∼10% and are increasing in
Externí odkaz:
https://doaj.org/article/d5b4c31c286a40738c8bcc9fc51a56c2
Autor:
Monika Gulia-Nuss, Andrew B. Nuss, Jason M. Meyer, Daniel E. Sonenshine, R. Michael Roe, Robert M. Waterhouse, David B. Sattelle, José de la Fuente, Jose M. Ribeiro, Karine Megy, Jyothi Thimmapuram, Jason R. Miller, Brian P. Walenz, Sergey Koren, Jessica B. Hostetler, Mathangi Thiagarajan, Vinita S. Joardar, Linda I. Hannick, Shelby Bidwell, Martin P. Hammond, Sarah Young, Qiandong Zeng, Jenica L. Abrudan, Francisca C. Almeida, Nieves Ayllón, Ketaki Bhide, Brooke W. Bissinger, Elena Bonzon-Kulichenko, Steven D. Buckingham, Daniel R. Caffrey, Melissa J. Caimano, Vincent Croset, Timothy Driscoll, Don Gilbert, Joseph J. Gillespie, Gloria I. Giraldo-Calderón, Jeffrey M. Grabowski, David Jiang, Sayed M. S. Khalil, Donghun Kim, Katherine M. Kocan, Juraj Koči, Richard J. Kuhn, Timothy J. Kurtti, Kristin Lees, Emma G. Lang, Ryan C. Kennedy, Hyeogsun Kwon, Rushika Perera, Yumin Qi, Justin D. Radolf, Joyce M. Sakamoto, Alejandro Sánchez-Gracia, Maiara S. Severo, Neal Silverman, Ladislav Šimo, Marta Tojo, Cristian Tornador, Janice P. Van Zee, Jesús Vázquez, Filipe G. Vieira, Margarita Villar, Adam R. Wespiser, Yunlong Yang, Jiwei Zhu, Peter Arensburger, Patricia V. Pietrantonio, Stephen C. Barker, Renfu Shao, Evgeny M. Zdobnov, Frank Hauser, Cornelis J. P. Grimmelikhuijzen, Yoonseong Park, Julio Rozas, Richard Benton, Joao H. F. Pedra, David R. Nelson, Maria F. Unger, Jose M. C. Tubio, Zhijian Tu, Hugh M. Robertson, Martin Shumway, Granger Sutton, Jennifer R. Wortman, Daniel Lawson, Stephen K. Wikel, Vishvanath M. Nene, Claire M. Fraser, Frank H. Collins, Bruce Birren, Karen E. Nelson, Elisabet Caler, Catherine A. Hill
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Ticks transmit a large number of pathogens that cause human diseases. Here, the authors sequence the genome of the tick Ixodes scapularisand uncover expansion of genes associated with parasitic processes unique to ticks and tick-host interactions.
Externí odkaz:
https://doaj.org/article/fa4043b3779c4d0db50b094e385f7e3b
Autor:
Tyler G. Lewy, Danielle K. Offerdahl, Jeffrey M. Grabowski, Eliza Kellman, Luwanika Mlera, Abhilash Chiramel, Marshall E. Bloom
Publikováno v:
Viruses, Vol 12, Iss 3, p 328 (2020)
The unfolded protein response (UPR) maintains protein-folding homeostasis in the endoplasmic reticulum (ER) and has been implicated as both beneficial and detrimental to flavivirus infection. Protein kinase R (PKR)-like endoplasmic reticulum kinase (
Externí odkaz:
https://doaj.org/article/9df49a33508843138551ce80ad68ee9d
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)
Tick-borne flaviviruses (TBFs) affect human health globally. Human vaccines provide protection against some TBFs, and antivirals are available, yet TBF-specific control strategies are limited. Advances in genomics offer hope to understand the viral c
Externí odkaz:
https://doaj.org/article/4f8fa469d85a4ac2a58bb2cdc61b7a66
Autor:
Jeffrey M. Grabowski, Konstantin A. Tsetsarkin, Dan Long, Dana P. Scott, Rebecca Rosenke, Tom G. Schwan, Luwanika Mlera, Danielle K. Offerdahl, Alexander G. Pletnev, Marshall E. Bloom
Publikováno v:
mBio, Vol 8, Iss 4 (2017)
ABSTRACT Ixodes scapularis ticks transmit many infectious agents that cause disease, including tick-borne flaviviruses (TBFVs). TBFV infections cause thousands of human encephalitis cases worldwide annually. In the United States, human TBFV infection
Externí odkaz:
https://doaj.org/article/38fb52528dc24fc5accb0d8e4d1bc6ea
Autor:
Ryan F. Relich, Jeffrey M. Grabowski
Publikováno v:
Clinical Microbiology Newsletter. 42:79-86
The global incidence of tick-borne infectious diseases has increased since the beginning of the 21st century. The expansion of tick populations into new geographic locations and a variety of anthropogenic and natural factors are all drivers of the in
Autor:
Ryan Kissinger, Jeffrey M. Grabowski
Publikováno v:
Curr Protoc Microbiol
Tick-borne viruses cause thousands of cases of disease worldwide every year. Specific countermeasures to many tick-borne viruses are not commercially available. Very little is known regarding tick-virus interactions and increasing this knowledge can
Publikováno v:
Access Microbiology. 1