Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Jeffrey M Sequeira"'
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177156 (2017)
Vitamin B12 (cobalamin) deficiency is prevalent worldwide and causes megaloblastic anemia and neurologic deficits. While the anemia can be treated, the neurologic deficits can become refractive to treatment as the disease progresses. Therefore, timel
Externí odkaz:
https://doaj.org/article/32b8c779672945b6855f858c8dfe3142
Autor:
Richard Eugene Frye, Leanna eDelhey, John eSlattery, Marie eTippett, Rebecca eWynne, Shannon eRose, Stephen Gregory Kahler, Sirish eBennuri, Stepan eMelnyk, Jeffrey M Sequeira, Edward eQuadros
Publikováno v:
Frontiers in Neuroscience, Vol 10 (2016)
Folate receptor α (FRα) autoantibodies (FRAAs) are prevalent in autism spectrum disorder (ASD). They disrupt the transportation of folate across the blood-brain barrier by binding to the FRα. Children with ASD with FRAAs have been reported to resp
Externí odkaz:
https://doaj.org/article/c0902c82739d45fdb45bce0e51028c45
Autor:
Jeffrey M Sequeira, Ankuri Desai, Maria I Berrocal-Zaragoza, Michelle M Murphy, Joan D Fernandez-Ballart, Edward V Quadros
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0152249 (2016)
The central nervous system continues to develop during gestation and after birth, and folate is an essential nutrient in this process. Folate deficiency and folate receptor alpha autoantibodies (FRα-AuAb) have been associated with pregnancy-related
Externí odkaz:
https://doaj.org/article/03648a1872024d7e903d3a59af7ba0cf
Publikováno v:
Nutrients
Volume 15
Issue 5
Pages: 1167
Volume 15
Issue 5
Pages: 1167
In a rat model, following exposure to rat folate receptor alpha antibodies (FRαAb) during gestation, FRαAb accumulates in the placenta and the fetus and blocks folate transport to the fetal brain and produces behavioral deficits in the offspring. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42f9d6d425e952216f30d005ba310edd
Autor:
Natasha Bobrowski-Khoury, Jeffrey M. Sequeira, Erland Arning, Teodoro Bottiglieri, Edward V. Quadros
Publikováno v:
Nutrients; Volume 14; Issue 12; Pages: 2397
Food fortification and folic acid supplementation during pregnancy have been implemented as strategies to prevent fetal malformations during pregnancy. However, with the emergence of conditions where folate metabolism and transport are disrupted, suc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a70ee4ad5043e7532bcc819731bf401
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c3fed86f3b6a9be11e51566bd87cbd7
https://doi.org/10.1096/fj.202101376rr
https://doi.org/10.1096/fj.202101376rr
Cellular uptake of vitamin B12 in humans is mediated by the endocytosis of the B12 carrier protein transcobalamin (TC) via its cognate cell surface receptor TCblR (or CD320), encoded by the CD320 gene(1). Because CD320 expression is associated with t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0edbdd320a37a3eac75221b5bb293d5
https://doi.org/10.1101/2021.08.16.456495
https://doi.org/10.1101/2021.08.16.456495
Publikováno v:
Journal of Personalized Medicine
Journal of Personalized Medicine, Vol 11, Iss 710, p 710 (2021)
Journal of Personalized Medicine, Vol 11, Iss 710, p 710 (2021)
Folate deficiency and folate receptor autoimmune disorder are major contributors to infertility, pregnancy related complications and abnormal fetal development including structural and functional abnormalities of the brain. Food fortification and pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99f097d819032730c1ddc5ea19c4e47f
https://pubmed.ncbi.nlm.nih.gov/34442354
https://pubmed.ncbi.nlm.nih.gov/34442354
Autor:
Gregory G, Gick, Kaveri, Arora, Jeffrey M, Sequeira, Yasumi, Nakayama, Shao-Chiang, Lai, Edward V, Quadros
Publikováno v:
Experimental cell research. 396(1)
Cellular uptake of vitamin B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7a123410e21b872f0908db3874276e3a
https://pubmed.ncbi.nlm.nih.gov/32898552
https://pubmed.ncbi.nlm.nih.gov/32898552
Publikováno v:
Autism Research and Treatment
Autism Research and Treatment, Vol 2020 (2020)
Autism Research and Treatment, Vol 2020 (2020)
Background. Biomarkers such as oxidative stress, folate receptor alpha (FRα) autoimmunity, and abnormal brain serotonin turnover are common in autism. Methods. Oxidative stress biomarkers with pro- and antioxidants were measured in the severe form o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eb7035694db193a5c89dca60e502148