Zobrazeno 1 - 10
of 388
pro vyhledávání: '"Jeffrey M Rosen"'
Autor:
Payam Shahi, Dongsu Park, Adam C Pond, Mamatha Seethammagari, Shin-Heng Chiou, Kyucheol Cho, Julienne L Carstens, William K Decker, Pierre D McCrea, Michael M Ittmann, Jeffrey M Rosen, David M Spencer
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30814 (2012)
Wnt signaling is crucial for a variety of biological processes, including body axis formation, planar polarity, stem cell maintenance and cellular differentiation. Therefore, targeted manipulation of Wnt signaling in vivo would be extremely useful. B
Externí odkaz:
https://doaj.org/article/ed933022595d4e3f83612a50ddccaa99
Autor:
Amy N Shore, Elena B Kabotyanski, Kevin Roarty, Martin A Smith, Yiqun Zhang, Chad J Creighton, Marcel E Dinger, Jeffrey M Rosen
Publikováno v:
PLoS Genetics, Vol 8, Iss 7, p e1002840 (2012)
Pregnancy-induced noncoding RNA (PINC) and retinoblastoma-associated protein 46 (RbAp46) are upregulated in alveolar cells of the mammary gland during pregnancy and persist in alveolar cells that remain in the regressed lobules following involution.
Externí odkaz:
https://doaj.org/article/edd1211b52174fa2bb87b24ead25b82f
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27841 (2011)
Stem cell antigen-1 (Sca-1 or Ly6A) is a glycosyl phostidylinositol (GPI)-anchored cell surface protein associated with both stem and progenitor activity, as well as tumor initiating-potential. However, at present the functional role for Sca-1 is poo
Externí odkaz:
https://doaj.org/article/ef9cd46a6d53417a9d17a111fc849a0a
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8581 (2010)
Erythropoiesis is a highly regulated and well-characterized developmental process responsible for providing the oxygen transport system of the body. However, few of the mechanisms involved in this process have been elucidated. Checkpoint Kinase 1 (Ch
Externí odkaz:
https://doaj.org/article/a4732a470ded4f9083098ce94d580fe4
Autor:
Na Zhao, Reid T. Powell, Xueying Yuan, Goeun Bae, Kevin P. Roarty, Fabio Stossi, Martina Strempfl, Michael J. Toneff, Hannah L. Johnson, Sendurai A. Mani, Philip Jones, Clifford C. Stephan, Jeffrey M. Rosen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
The epithelial-mesenchymal transition (EMT) has been implicated in stem cell properties and therapeutic resistance in cancer. Here, the authors show organoids derived from mesenchymal breast cancers exhibit a spikey structure which can be reverted an
Externí odkaz:
https://doaj.org/article/4bf1f86424d4458c89d66da69cca86c8
Autor:
Geraldine Vidhya Vijay, Na Zhao, Petra Den Hollander, Mike J. Toneff, Robiya Joseph, Mika Pietila, Joseph H. Taube, Tapasree R. Sarkar, Esmeralda Ramirez-Pena, Steven J. Werden, Maryam Shariati, Ruli Gao, Mary Sobieski, Clifford C. Stephan, Nathalie Sphyris, Noayuki Miura, Peter Davies, Jeffrey T. Chang, Rama Soundararajan, Jeffrey M. Rosen, Sendurai A. Mani
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-14 (2019)
Abstract Background Triple-negative breast cancers (TNBCs), which lack receptors for estrogen, progesterone, and amplification of epidermal growth factor receptor 2, are highly aggressive. Consequently, patients diagnosed with TNBCs have reduced over
Externí odkaz:
https://doaj.org/article/94966eb44ff14ce28f1cf950c225b5fb
Publikováno v:
American Journal of Physiology-Cell Physiology. 324:C707-C717
A better understanding of the mechanisms regulating cancer metastasis is critical to develop new therapies and decrease mortality. Emerging evidence suggests that the interactions between tumor cells and the host immune system play important roles in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f3789eed45623237848179ede37fcd5
https://doi.org/10.1152/ajpcell.00132.2022
https://doi.org/10.1152/ajpcell.00132.2022
Autor:
Ho Ngai, Gabriel A. Barragan, Gengwen Tian, Julien C. Balzeau, Chunchao Zhang, Amy N. Courtney, Linjie Guo, Xin Xu, Michael S. Wood, Janice M. Drabek, Thorsten Demberg, Caroline M. Sands, Cynthia N. Chauvin-Fleurence, Erica J. Di Pierro, Jeffrey M. Rosen, Leonid S. Metelitsa
Publikováno v:
Cancer Immunology Research. 11:171-183
Vα24-invariant natural killer T cells (NKT) possess innate antitumor properties that can be exploited for cancer immunotherapy. We have shown previously that the CD62L+ central memory-like subset of these cells drives the in vivo antitumor activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::266a7555c7aed7fade7dfb0cb68f67ab
https://doi.org/10.1158/2326-6066.cir-22-0333
https://doi.org/10.1158/2326-6066.cir-22-0333
Publikováno v:
Seminars in Cancer Biology. 87:17-31
Metastatic cancer is almost always terminal, and more than 90% of cancer deaths result from metastatic disease. Combating cancer metastasis and post-therapeutic recurrence successfully requires understanding each step of metastatic progression. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9040e633a3593c110641145095a87308
https://doi.org/10.1016/j.semcancer.2022.10.006
https://doi.org/10.1016/j.semcancer.2022.10.006
Autor:
Peng Zhang, Dandan He, Yi Xu, Jiakai Hou, Bih-Fang Pan, Yunfei Wang, Tao Liu, Christel M. Davis, Erik A. Ehli, Lin Tan, Feng Zhou, Jian Hu, Yonghao Yu, Xi Chen, Tuan M. Nguyen, Jeffrey M. Rosen, David H. Hawke, Zhe Ji, Yiwen Chen
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Translation initiation sequencing (TI-seq) has revealed unexpected diversity in protein isoforms. Here, Zhang et al. present Ribo-TISH, a computational toolkit that can detect and compare TIs across conditions and improve open reading frame predictio
Externí odkaz:
https://doaj.org/article/825c960c001f405889d594142c4c5f57