Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Jeffrey M Macdonald"'
Autor:
Kelsey A Behrens, Leigh A Jania, John N Snouwaert, MyTrang Nguyen, Sheryl S Moy, Andrey P Tikunov, Jeffrey M Macdonald, Beverly H Koller
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0225449 (2019)
Environmental and endogenous electrophiles cause tissue damage through their high reactivity with endogenous nucleophiles such as DNA, proteins, and lipids. Protection against damage is mediated by glutathione (GSH) conjugation, which can occur spont
Externí odkaz:
https://doaj.org/article/3bfefc70a31c4aed8966846980f44286
Autor:
Wagner R de Souza, Enyara Rezende Morais, Nadia Graciele Krohn, Marcela Savoldi, Maria Helena S Goldman, Fernando Rodrigues, Camila Caldana, Charles T Semelka, Andrey P Tikunov, Jeffrey M Macdonald, Gustavo Henrique Goldman
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e62088 (2013)
Heterotrimeric G-protein-mediated signaling pathways play a pivotal role in transmembrane signaling in eukaryotes. Our main aim was to identify signaling pathways regulated by A. nidulans GprB and GprD G-protein coupled receptors (GPCRs). When these
Externí odkaz:
https://doaj.org/article/afaca6b4026e48bdb5aadce3e3dd7ae4
Autor:
Nora Grahl, Srisombat Puttikamonkul, Jeffrey M Macdonald, Michael P Gamcsik, Lisa Y Ngo, Tobias M Hohl, Robert A Cramer
Publikováno v:
PLoS Pathogens, Vol 7, Iss 7, p e1002145 (2011)
Currently, our knowledge of how pathogenic fungi grow in mammalian host environments is limited. Using a chemotherapeutic murine model of invasive pulmonary aspergillosis (IPA) and (1)H-NMR metabolomics, we detected ethanol in the lungs of mice infec
Externí odkaz:
https://doaj.org/article/7c8b88691c41411094bf40d2fb20300f
Autor:
Timothy R. Gershon, Jeffrey M. Macdonald, Michael D. Taylor, Matthew G. Vander Heiden, Marco A. Marra, Steven J.M. Jones, Yussanne Ma, Richard A. Moore, Andrew J. Mungall, Yisu Li, Hedi Liu, Sarah C. Green, Taylor Fish, Jessica Meidinger, A. Sorana Morrissy, Hamza Farooq, Andrey P. Tikunov, Katherine Tech
Aerobic glycolysis supports proliferation through unresolved mechanisms. We have previously shown that aerobic glycolysis is required for the regulated proliferation of cerebellar granule neuron progenitors (CGNP) and for the growth of CGNP-derived m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0953d4b7888e9c257f083e6df8d2e173
https://doi.org/10.1158/0008-5472.c.6508454
https://doi.org/10.1158/0008-5472.c.6508454
Autor:
Timothy R. Gershon, Jeffrey M. Macdonald, Michael D. Taylor, Matthew G. Vander Heiden, Marco A. Marra, Steven J.M. Jones, Yussanne Ma, Richard A. Moore, Andrew J. Mungall, Yisu Li, Hedi Liu, Sarah C. Green, Taylor Fish, Jessica Meidinger, A. Sorana Morrissy, Hamza Farooq, Andrey P. Tikunov, Katherine Tech
Immunofluorescence for PKM1 and PCNA demonstrates that PKM1+ cells within medulloblastomas are PCNA-.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ffacfc5278336dcd554cfec7207ca1a
https://doi.org/10.1158/0008-5472.22412498
https://doi.org/10.1158/0008-5472.22412498
Autor:
Timothy R. Gershon, Jeffrey M. Macdonald, Michael D. Taylor, Matthew G. Vander Heiden, Marco A. Marra, Steven J.M. Jones, Yussanne Ma, Richard A. Moore, Andrew J. Mungall, Yisu Li, Hedi Liu, Sarah C. Green, Taylor Fish, Jessica Meidinger, A. Sorana Morrissy, Hamza Farooq, Andrey P. Tikunov, Katherine Tech
Rates of change of select media metabolites in 24 hour cultures of CGNPs, with and without Pkm2 deletion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f1012033d22afd2684664891cccc3ca
https://doi.org/10.1158/0008-5472.22412489
https://doi.org/10.1158/0008-5472.22412489
Autor:
Timothy R. Gershon, Jeffrey M. Macdonald, Michael D. Taylor, Matthew G. Vander Heiden, Marco A. Marra, Steven J.M. Jones, Yussanne Ma, Richard A. Moore, Andrew J. Mungall, Yisu Li, Hedi Liu, Sarah C. Green, Taylor Fish, Jessica Meidinger, A. Sorana Morrissy, Hamza Farooq, Andrey P. Tikunov, Katherine Tech
Supplementary Materials and Methods, including NMR, LC-MS and RNA-seq methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35bdc4d60084946a62e3b9d15cf53263
https://doi.org/10.1158/0008-5472.22412492.v1
https://doi.org/10.1158/0008-5472.22412492.v1
Author Correction: Nano-fibre Integrated Microcapsules: A Nano-in-Micro Platform for 3D Cell Culture
Autor:
Shalil Khanal, Shanta R. Bhattarai, Jagannathan Sankar, Ramji K. Bhandari, Jeffrey M. Macdonald, Narayan Bhattarai
Publikováno v:
Scientific Reports. 13
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 9; Pages: 4733
Nuclear magnetic resonance (NMR) spectroscopy was used to monitor glutathione metabolism in alginate-encapsulated JM-1 hepatoma cells perfused with growth media containing [3,3′-13C2]-cystine. After 20 h of perfusion with labeled medium, the 13C NM
Autor:
Andrey P, Tikunov, Jeremiah D, Tipton, Timothy J, Garrett, Sachi V, Shinde, Hong Jin, Kim, David A, Gerber, Laura E, Herring, Lee M, Graves, Jeffrey M, Macdonald
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2394
The Environmental Protection Agency's definition of "Green Chemistry" is "the design of chemical products and processes that reduces or eliminates the use or generation of hazardous substances. Green chemistry applies across the life cycle of a chemi