Výsledky vyhledávání - "Jeffrey Lochhead"

Abstract TP209: Role Of Endoglin In The Regulation Of Organic Anion Transporting Polypeptide 1a4 At The Blood-brain Barrier: Relevance To The Treatment Of Ischemic Stroke

Autor: Robert Betterton, Erica I Williams, Joshua Stanton, Jeffrey Lochhead, Tom Davis, Patrick Ronaldson

Publikováno v: Stroke. 54

Objectives: We have shown that transforming growth factor-β (TGF-β)/activin-like kinase 1 (ALK1) signaling at the blood-brain barrier (BBB) can regulate organic anion transporting polypeptide 1a4 (Oatp1a4), a transporter involved in brain uptake of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9835402b64986f28f1a1d810a461cf8d
https://doi.org/10.1161/str.54.suppl_1.tp209

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Abstract WP244: Localization And Expression Of Transporters For Cationic Drugs At The Blood-brain Barrier: Relevance To The Pharmacotherapy Of Ischemic Stroke

Autor: Joshua Stanton, Erica I Williams, Robert Betterton, Jeffrey Lochhead, Thomas Davis, Patrick Ronaldson

Publikováno v: Stroke. 54

Purpose: Cationic drugs have often been considered for stroke treatment but their utility is dependent upondelivery across the blood-brain barrier (BBB). This process can involve transporters for cationic substratessuch as organic cation transporters

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dba37c64474fba09ebc0f14a3ee17a6b
https://doi.org/10.1161/str.54.suppl_1.wp244

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