Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jeffrey Landrigan"'
Autor:
Jessica Parnell, Newton Martin, Annemarie Dedek, Christopher Rudyk, Jeffrey Landrigan, Justin Bellavance, Simon VanDerLoo, Eve C. Tsai, Michael E. Hildebrand
Publikováno v:
Canadian Journal of Pain, Vol 7, Iss 2 (2023)
ABSTRACTBackground Preclinical and clinical evidence suggests that cannabis has potential analgesic properties. However, cannabinoid receptor expression and localization within spinal cord pain processing circuits remain to be characterized across se
Externí odkaz:
https://doaj.org/article/a5acdba8de16455fb796df26bd63e359
Autor:
Zach Dwyer, Melany Chaiquin, Jeffrey Landrigan, Kiara Ayoub, Pragya Shail, Julianna Rocha, Christie L. Childers, Kenneth B. Storey, Dana J. Philpott, Hongyu Sun, Shawn Hayley
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-15 (2021)
Abstract Background Recent work has established that Parkinson’s disease (PD) patients have an altered gut microbiome, along with signs of intestinal inflammation. This could help explain the high degree of gastric disturbances in PD patients, as w
Externí odkaz:
https://doaj.org/article/ae51a5980fbe41598abca705b69ffe6e
Autor:
Jeffrey Landrigan, Chris Dedek, Natalina Salmaso, Michael E. Hildebrand, Jennifer M Armstrong, Santa Temi, Christopher Rudyk
Publikováno v:
Channels
article-version (VoR) Version of Record
article-version (VoR) Version of Record
N-methyl-D-aspartate receptors (NMDARs) are excitatory ionotropic glutamate receptors expressed throughout the CNS, including in the spinal dorsal horn. The GluN2 subtypes of NMDAR subunit, which include GluN2A, GluN2B, and GluN2D in the dorsal horn,
Publikováno v:
NeuroToxicology. 76:153-161
Parkinson's disease (PD) is characterized by profound microglial driven inflammatory processes and the loss of dopamine neurons of the substantia nigra (SNc). Both microglia and dopamine neurons that are affected in the SNc are particularly vulnerabl
Autor:
Chaya M. Kandegedara, Annemarie Dedek, Yves De Koninck, Paul J. Lombroso, Eve C. Tsai, Jeffrey Landrigan, Geneviève Glavina, Michael E. Hildebrand, Antoine G. Godin, Louis-Etienne Lorenzo, Jian Xu
The prevalence and severity of many chronic pain syndromes differ across sex, and recent studies have identified differences in immune signalling within spinal nociceptive circuits as a potential mediator. Although it has been proposed that sex-speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb65003cad7f70c5aeac0846dfc57ba6
https://doi.org/10.1101/2021.06.15.447407
https://doi.org/10.1101/2021.06.15.447407
Autor:
Zach Dwyer, Jeffrey Landrigan, Julianna Rocha, Shawn Hayley, Kiara Ayoub, Christie L. Childers, Kenneth B. Storey, Melany Chaiquin, Hongyu Sun, Dana J. Philpott, Pragya Shail
Publikováno v:
Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-15 (2021)
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-15 (2021)
Background Recent work has established that Parkinson’s disease (PD) patients have an altered gut microbiome, along with signs of intestinal inflammation. This could help explain the high degree of gastric disturbances in PD patients, as well as po
Autor:
Damian Leitner, Jennifer L. Prentice, John D. Fisk, Jeffrey Landrigan, Kitti Bessenyei, Igor Yakovenko
Publikováno v:
Multiple Sclerosis and Related Disorders. 57:103338
Background : Multiple sclerosis (MS) is a chronic demyelinating disease which leads to sensory, motor, autonomic, and cognitive symptoms. Cannabis is a common way for persons with MS (pwMS) to seek symptomatic therapy. Given the capacity for both can
Publikováno v:
Neuroscience letters. 669
The efficacy of ketamine to alleviate depressive symptoms has promoted a wealth of research exploring alternate therapeutic targets for depression. Given the caveats of ketamine treatment taken together with the increasingly greater emphasis on combi