Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Jeffrey L. Osborn"'
Autor:
Jacqueline R. Leachman, Sundus Ghuneim, Jeffrey L. Osborn, Nermin Ahmed, Olivier Thibault, Carolina Dalmasso, Eve R. Schneider, Analia S. Loria
Publikováno v:
Hypertension (Dallas, Tex. : 1979)
Supplemental Digital Content is available in the text.
Previously, we have shown that male mice exposed to maternal separation and early weaning (MSEW)—a mouse model of early life stress—display increased mean arterial pressure compared with
Previously, we have shown that male mice exposed to maternal separation and early weaning (MSEW)—a mouse model of early life stress—display increased mean arterial pressure compared with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1afadd0dcd806def07d51b11e52745c5
https://doi.org/10.1161/hypertensionaha.121.17298
https://doi.org/10.1161/hypertensionaha.121.17298
Publikováno v:
Am J Physiol Regul Integr Comp Physiol
Blood pressure regulation in health and disease involves a balance between afferent and efferent signals from multiple organs and tissues. Although there are numerous reviews focused on the role of sympathetic nerves in different models of hypertensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c653ef7532680ba146d0a937015e631
https://doi.org/10.1152/ajpregu.00079.2019
https://doi.org/10.1152/ajpregu.00079.2019
Autor:
Shyam S. Mohapatra, Suttira Intapad, Bo Pang, Larry Qu, Jin Wei, Kun Jiang, Jeffrey L. Osborn, Feng Cheng, Luis A. Juncos, Lei Wang, Joey P. Granger, Ruisheng Liu, Shan Jiang, Jie Zhang, Lan Xu, Jacentha Buggs
Publikováno v:
J Am Soc Nephrol
Background: Regulation of renal hemodynamics and blood pressure (BP) via tubuloglomerular feedback (TGF) may be an important adaptive mechanism during pregnancy. Because the β-splice variant of nitric oxide synthase 1 (NOS1β) in the macula densa is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfd39d80db43a3c5b37052cd30e3328c
https://europepmc.org/articles/PMC8722793/
https://europepmc.org/articles/PMC8722793/
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0136441 (2015)
Mitochondrial (Mt) dysfunction contributes to the pathophysiology of renal function and promotes cardiovascular disease such as hypertension. We hypothesize that renal Mt-genes derived from female spontaneously hypertensive rats (SHR) that exhibit hy
Externí odkaz:
https://doaj.org/article/3350e1791e134847a8ed161fe34c14f7
Autor:
Analia S. Loria, Nermin Ahmed, Carolina Dalmasso, Sundus Ghuneim, Jacqueline R. Leachman, Jeffrey L. Osborn
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6e4f75836ce10cce750aa35dd32152b
https://doi.org/10.1096/fasebj.2021.35.s1.02312
https://doi.org/10.1096/fasebj.2021.35.s1.02312
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6809bc0b4d67a66b32100f556290b90
https://doi.org/10.1096/fasebj.2021.35.s1.04344
https://doi.org/10.1096/fasebj.2021.35.s1.04344
Publikováno v:
Am J Physiol Regul Integr Comp Physiol
(Pro)renin receptor (PRR), a 350-amino acid receptor initially thought of as a receptor for the binding of renin and prorenin, is multifunctional. In addition to its role in the renin-angiotensin system (RAS), PRR transduces several intracellular sig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47456036a48e09ac62c527354f4d9bd8
https://pubmed.ncbi.nlm.nih.gov/33470188
https://pubmed.ncbi.nlm.nih.gov/33470188
Autor:
Steven Krakowka, Kara Fitzgerald, Ryan G. Rhodes, Sunthorn Pond-Tor, John Mcmichael, Jeffrey L. Osborn, Albert E. Dahlberg, Sarah Beseme, Lloyd Saberski, Stephen W. Mamber, Neal Wright
Publikováno v:
mSphere
mSphere, Vol 5, Iss 3 (2020)
mSphere, Vol 5, Iss 3, p e00288-20 (2020)
mSphere, Vol 5, Iss 3 (2020)
mSphere, Vol 5, Iss 3, p e00288-20 (2020)
Severe acute respiratory syndrome coronavirus 2 (SARS coronavirus 2, or SARS-CoV-2) is the cause of the respiratory infection known as COVID-19. From an immunopathological standpoint, coronaviruses such as SARS-CoV-2 induce increased levels of a vari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5285f1982992990091d38d2b1d87e205
https://doi.org/10.1128/msphere.00288-20
https://doi.org/10.1128/msphere.00288-20
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 313:R211-R218
Hypertension is a complex, multifactorial disease affecting an estimated 78 million adults in the United States. Despite scientific gains, the etiology of human essential hypertension is unknown and current experimental models do not recapitulate all
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4bf0c1d3376613e4ae5c3f8e3972fd1
https://doi.org/10.1152/ajpregu.00026.2017
https://doi.org/10.1152/ajpregu.00026.2017
Publikováno v:
Mechanisms of Development. 146:42-54
Little is known about the potential for ion channels to regulate cellular behaviors during tissue regeneration. Here, we utilized an amphibian tail regeneration assay coupled with a chemical genetic screen to identify ion channel antagonists that alt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b488b3f25db123ac3b6b109d857a419
https://doi.org/10.1016/j.mod.2017.06.001
https://doi.org/10.1016/j.mod.2017.06.001