Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jeffrey L. Boldt"'
Publikováno v:
Journal of Bacteriology. 191:2169-2176
Peptide inhibitors of phage lambda site-specific recombination were previously isolated by screening synthetic combinatorial peptide libraries. These inhibitors cause the accumulation of complexes between the recombinase and the Holliday junction int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59c04393aa523ea1a5a5311ddc728373
https://doi.org/10.1128/jb.01559-08
https://doi.org/10.1128/jb.01559-08
Publikováno v:
Nucleic Acids Research
Holliday junctions are a central intermediate in diverse pathways of DNA repair and recombination. The isomerization of a junction determines the directionality of the recombination event. Previous studies have shown that the identity of the central
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e97623289c9902ef1b436f99e343e023
https://doi.org/10.1093/nar/gkl1078
https://doi.org/10.1093/nar/gkl1078
Publikováno v:
Journal of Biological Chemistry. 279:3472-3483
The bacteriophage lambda integrase catalyzes four site-specific recombination pathways with distinct protein and DNA requirements and nucleoprotein intermediates. Some of these intermediates are very transient and difficult to obtain in significant a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98fccca273306f06ab1ca7fdf816cf78
https://doi.org/10.1074/jbc.m309361200
https://doi.org/10.1074/jbc.m309361200
Autor:
Bernard J. Etzel, Anca M. Segall, Sylvain Bordenave, Jeffrey L. Boldt, Teresa A. Larsen, Troy Bankhead, Felise Wolven
Publikováno v:
Journal of Bacteriology. 185:2653-2666
Bacteriophage λ integrase (Int) catalyzes site-specific recombination between pairs of attachment (att) sites. Theattsites contain weak Int-binding sites called core-type sites that are separated by a 7-bp overlap region, where cleavage and strand e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8e731bb8c43700f7f1c7fdffd327068
https://doi.org/10.1128/jb.185.8.2653-2666.2003
https://doi.org/10.1128/jb.185.8.2653-2666.2003
Autor:
Ilham Naili, Jason E. Rostron, America Flores-Fujimoto, Sukanya Patra, Anca M. Segall, Jeffrey L. Boldt, Marc C. Rideout
DNA repair pathways in bacteria that use homologous recombination involve the formation and subsequent resolution of Holliday junction (HJ) intermediates. We have previously identified several hexameric peptides that bind to HJs and interfere with HJ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7475faf28e33ddf8d19e05d406cfa9b9
https://europepmc.org/articles/PMC3646928/
https://europepmc.org/articles/PMC3646928/
Autor:
Marc C. Rideout, Marc A. Giulianotti, Peter Salamon, John M. Ostresh, Gabriel Vahi-Ferguson, Clemencia Pinilla, Adel Nefzi, Anca M. Segall, Jeffrey L. Boldt
Publikováno v:
Molecular diversity. 15(4)
Holliday junctions (HJs) are critical intermediates in many recombination-dependent DNA repair pathways. Our lab has previously identified several hexameric peptides that target HJ intermediates formed in DNA recombination reactions. One of the most
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4878df64b80d18e095a62ebe92972cf0
https://pubmed.ncbi.nlm.nih.gov/21938393
https://pubmed.ncbi.nlm.nih.gov/21938393
Holliday junctions (HJ) are the central intermediates in both homologous recombination and site-specific recombination performed by tyrosine recombinases such as the bacteriophage λ Integrase (Int) protein. Previously, our lab identified peptide inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5be975a0bff384ca06c7f9eba2fb6448
https://europepmc.org/articles/PMC1100769/
https://europepmc.org/articles/PMC1100769/