Zobrazeno 1 - 10
of 312
pro vyhledávání: '"Jeffrey L. Benovic"'
Autor:
Robert J. Lefkowitz, Howard A. Rockman, Paul J. Shim, Samuel Liu, Seungkirl Ahn, Biswaranjan Pani, Sudarshan Rajagopal, Sudha K. Shenoy, Michel Bouvier, Jeffrey L. Benovic, Stephen B. Liggett, Robert R. Ruffolo, Michael R. Bristow, Milton Packer
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/1516c52dd4af4fd98dff325b5997c3e9
Autor:
Dominic Lapadula, Jeffrey L. Benovic
Publikováno v:
Cancers, Vol 13, Iss 24, p 6195 (2021)
Uveal melanoma is the most common intraocular cancer in adults and arises from the transformation of melanocytes in the uveal tract. While treatment of the primary tumor is often effective, 36–50% of patients develop metastatic disease primarily to
Externí odkaz:
https://doaj.org/article/2e6d88484f6547558c93137c86883c5f
Autor:
Mizue Terai, Ayako Shimada, Inna Chervoneva, Liam Hulse, Meggie Danielson, Jeff Swensen, Marlana Orloff, Philip B. Wedegaertner, Jeffrey L. Benovic, Andrew E. Aplin, Takami Sato
Publikováno v:
Cancers, Vol 13, Iss 22, p 5749 (2021)
Uveal melanoma is the most common primary ocular malignancy in adults, characterized by gene mutations in G protein subunit alpha q (GNAQ) and G protein subunit alpha 11 (GNA11). Although they are considered to be driver mutations, their role in MUM
Externí odkaz:
https://doaj.org/article/86a4c271f81742bab04b74ded1bf5119
Autor:
Jeffrey L. Benovic
Publikováno v:
Cells, Vol 10, Iss 3, p 555 (2021)
Agonist activation of G protein-coupled receptors promotes sequential interaction of the receptor with heterotrimeric G proteins, G protein-coupled receptor kinases (GRKs), and arrestins. GRKs play a central role in mediating the switch from G protei
Externí odkaz:
https://doaj.org/article/8897bf9fe0d64c22bd27fc653b6f1edd
Autor:
Eric Tompkins, Bogdana Mimic, Karina Cuevas-Mora, Hannah Schorsch, Sushrut D. Shah, Deepak A. Deshpande, Jeffrey L. Benovic, Raymond B. Penn, Tonio Pera
Publikováno v:
American journal of respiratory cell and molecular biology. 67(5)
G protein-coupled receptors (GPCRs) not only are turned on or off to control canonical G protein signaling but also may be fine-tuned to promote qualitative/biased signaling. Qualitative signaling by M3 muscarinic acetylcholine receptors (mAChRs) has
Publikováno v:
ASPET 2023 Annual Meeting Abstract - Cellular and Molecular Pharmacology.
Autor:
Francesco F. De Pascali, Michael Ippolito, Nathan Hopfinger, Konstantin E. Komolov, Daniela K. Laurinavichyute, Leon A. Sakkal, Ajay P. Nayak, Poli AN. Reddy, Preston S. Donover, Melvin Reichman, Joseph M. Salvino, Raymond B. Penn, Roger S. Armen, Charles P. Scott, Jeffrey L. Benovic
Publikováno v:
ASPET 2023 Annual Meeting Abstract - Cellular and Molecular Pharmacology.
Autor:
Francesco De Pascali, Michael Ippolito, Emily Wolfe, Konstantin E. Komolov, Nathan Hopfinger, Douglas Lemenze, Nicholas Kim, Roger S. Armen, Steven S. An, Charles P. Scott, Jeffrey L. Benovic
Publikováno v:
British Journal of Pharmacology. 179:4692-4708
Autor:
Jeffrey L. Benovic, Julio Aguirre-Ghiso, Andrew E. Aplin, Philip B. Wedegaertner, Naiming Zhou, Gregory G. Tall, Takami Sato, Mizue Terai, Shihua Wu, Lihong Zhang, Thomas H. Charpentier, Dougan McGrath, Timothy J. Purwin, Clinita E. Randolph, Eduardo Farias, Dominic Lapadula
GNAQ and GNA11 sequence analysis of UM002B cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc86c2aecfa02c9d2318332d673c3913
https://doi.org/10.1158/1541-7786.22513482.v1
https://doi.org/10.1158/1541-7786.22513482.v1
Autor:
Joshua B. Rubin, David Piwnica-Worms, Jeffrey L. Benovic, Paul Mischel, Sonika M. Dahiya, Erin Jackson, Kristin R. Brown, Jingqin Luo, B. Mark Woerner
G-protein–coupled receptor kinases (GRK) regulate the function of G-protein–coupled receptors (GPCR). Previously, we found that GPCR (CXCR4)-mediated astrocytoma growth was dependent upon abnormally sustained CXCR4 signaling and was correlated wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba9350af291d5eaa89fbff750b67f039
https://doi.org/10.1158/1541-7786.c.6541540
https://doi.org/10.1158/1541-7786.c.6541540