Zobrazeno 1 - 10
of 245
pro vyhledávání: '"Jeffrey L Ebersole"'
Autor:
Jeffrey L Ebersole, Octavio A Gonzalez
Publikováno v:
PLoS ONE, Vol 17, Iss 12, p e0275199 (2022)
As circadian processes can impact the immune system and are affected by infections and inflammation, this study examined the expression of circadian rhythm genes in periodontitis.MethodsMacaca mulatta were used with naturally-occurring and ligature-i
Externí odkaz:
https://doaj.org/article/2c13b69c979f469791d40d1ab70dc272
Autor:
Jeffrey L Ebersole, Sreenatha S Kirakodu, M. John Novak, Luis Orraca, Larry L Cunningham, Mark V Thomas, Arnold Stromberg, Subramanya N Pandruvada, Janis Gonzalez Martinez
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
Evidence has shown activation of T and B cells in gingival tissues in experimental models and in humans diagnosed with periodontitis. The results of this adaptive immune response are noted both locally and systemically with antigenic specificity for
Externí odkaz:
https://doaj.org/article/aceec01fa4914dc6b20f7823c8281130
Autor:
Radhakrishnan Nagarajan, Craig S Miller, Dolph Dawson, Mohanad Al-Sabbagh, Jeffrey L Ebersole
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0136792 (2015)
This study investigates the use of saliva, as an emerging diagnostic fluid in conjunction with classification techniques to discern biological heterogeneity in clinically labelled gingivitis and periodontitis subjects (80 subjects; 40/group) A batter
Externí odkaz:
https://doaj.org/article/e31f8d11df314b1db71f423e4be465ae
Comparative Analysis of Gene Expression Patterns for Oral Epithelial Cell Functions in Periodontitis
Autor:
Octavio A. Gonzalez, Sreenatha Kirakodu, Linh M. Nguyen, Luis Orraca, Michael J. Novak, Janis Gonzalez-Martinez, Jeffrey L. Ebersole
Publikováno v:
Frontiers in Oral Health, Vol 3 (2022)
The structure and function of epithelial cells are critical for the construction and maintenance of intact epithelial surfaces throughout the body. Beyond the mechanical barrier functions, epithelial cells have been identified as active participants
Externí odkaz:
https://doaj.org/article/93da86d21d604aef9de58fcb9d2920de
Publikováno v:
Journal of Periodontal Research. 58:493-502
Autor:
Jeffrey L. Ebersole, Sreenatha S. Kirakodu, Elliot Neumann, Luis Orraca, Janis Gonzalez Martinez, Octavio A. Gonzalez
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Objective: This study focused on documenting characteristics of the gingival transcriptome during various stages of periodontitis targeting genes associated with apoptotic and autophagic pathways and changes that specifically associate with features
Externí odkaz:
https://doaj.org/article/7a2588aa159b448fb5eb514ae346991e
Publikováno v:
Clinical and Experimental Immunology. 211:248-268
Phenotypic and functional heterogeneity of macrophages is clearly a critical component of their effective functions in innate and adaptive immunity. This investigation hypothesized that altered profiles of gene expression in gingival tissues in healt
Publikováno v:
Molecular Oral Microbiology. 38:93-114
Rhesus monkeys (n = 36) exhibiting a healthy periodontium at baseline were used to induce progressing periodontitis through ligature placement around premolar/molar teeth. Bacterial samples were collected at baseline, 0.5, 1, and 3 months of disease
Publikováno v:
Journal of Periodontology.
Publikováno v:
Journal of Periodontal Research. 57:780-798
This study used a nonhuman primate model of ligature-induced periodontitis to document the characteristics of immunoglobulin (Ig) gene usage in gingival tissues with disease and affected by age.Adaptive immune responses to an array of oral bacteria a